WO2009150530A3 - Pharmaceutical composition suitable for use as foam comprising 5'-aminosalicylic acid and silicone oil - Google Patents

Pharmaceutical composition suitable for use as foam comprising 5'-aminosalicylic acid and silicone oil Download PDF

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Publication number
WO2009150530A3
WO2009150530A3 PCT/IB2009/006005 IB2009006005W WO2009150530A3 WO 2009150530 A3 WO2009150530 A3 WO 2009150530A3 IB 2009006005 W IB2009006005 W IB 2009006005W WO 2009150530 A3 WO2009150530 A3 WO 2009150530A3
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceutical composition
foam
silicone oil
composition suitable
aminosalicylic acid
Prior art date
Application number
PCT/IB2009/006005
Other languages
French (fr)
Other versions
WO2009150530A2 (en
Inventor
Jean Marc Aiache
Original Assignee
Ferring International Center Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring International Center Sa filed Critical Ferring International Center Sa
Publication of WO2009150530A2 publication Critical patent/WO2009150530A2/en
Publication of WO2009150530A3 publication Critical patent/WO2009150530A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/606—Salicylic acid; Derivatives thereof having amino groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/122—Foams; Dry foams

Abstract

The present invention relates to novel pharmaceutical compositions suitable for use as foams, notably rectal foams. According to the present invention there is provided a pharmaceutical composition suitable for use as a foam comprising 5 -ASA or a pharmaceutically acceptable salt thereof and a silicone oil. The pharmaceutical composition may remain substantially fluid upon pressurisation, avoiding, for example, significant crystallisation of the active principle. The pharmaceutical composition also provides further physical advantages such as dose reproducibility of the active principle and, if crystallisation does occur, ease of re- suspension. The invention additionally provides a complementary delivery device and/or enhanced foam-forming properties of the pharmaceutical composition.
PCT/IB2009/006005 2008-06-11 2009-06-10 Novel foam composition WO2009150530A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08252010.7 2008-06-11
EP08252010 2008-06-11

Publications (2)

Publication Number Publication Date
WO2009150530A2 WO2009150530A2 (en) 2009-12-17
WO2009150530A3 true WO2009150530A3 (en) 2010-10-28

Family

ID=39876579

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2009/006005 WO2009150530A2 (en) 2008-06-11 2009-06-10 Novel foam composition

Country Status (1)

Country Link
WO (1) WO2009150530A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2359812C (en) 2000-11-20 2004-02-10 The Procter & Gamble Company Pharmaceutical dosage form with multiple coatings for reduced impact of coating fractures
KR20190110092A (en) * 2016-12-16 2019-09-27 훼링 비.브이. Rectal Foam Formulations

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4933330A (en) * 1987-04-01 1990-06-12 Dak-Laboratoriet Benzoic acid derivatives and use thereof
US5378470A (en) * 1989-07-25 1995-01-03 Henning Berlin Gmbh Rectally administered pharmaceutical preparation
US5725872A (en) * 1993-12-14 1998-03-10 Ferring Bv Composition for foams, notably rectal foams, and foams thus obtained
WO2007082698A1 (en) * 2006-01-19 2007-07-26 Disphar International B.V. Foam-forming composition

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4933330A (en) * 1987-04-01 1990-06-12 Dak-Laboratoriet Benzoic acid derivatives and use thereof
US5378470A (en) * 1989-07-25 1995-01-03 Henning Berlin Gmbh Rectally administered pharmaceutical preparation
US5725872A (en) * 1993-12-14 1998-03-10 Ferring Bv Composition for foams, notably rectal foams, and foams thus obtained
WO2007082698A1 (en) * 2006-01-19 2007-07-26 Disphar International B.V. Foam-forming composition

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BOU KARAM M ET AL: "First approach to the development of a colonic stimuli-sensitive delivery system for rectal administration of 5-aminosalicylic acid", S.T.P. PHARMA SCIENCES 1995 FR, vol. 5, no. 1, 1995, pages 89 - 92, XP008098257, ISSN: 1157-1489 *

Also Published As

Publication number Publication date
WO2009150530A2 (en) 2009-12-17

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