WO2009068275A3 - α-AMINOSÄUREDERIVATE ZUR LÖSLICHKEITSVERBESSERUNG - Google Patents

α-AMINOSÄUREDERIVATE ZUR LÖSLICHKEITSVERBESSERUNG Download PDF

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Publication number
WO2009068275A3
WO2009068275A3 PCT/EP2008/010045 EP2008010045W WO2009068275A3 WO 2009068275 A3 WO2009068275 A3 WO 2009068275A3 EP 2008010045 W EP2008010045 W EP 2008010045W WO 2009068275 A3 WO2009068275 A3 WO 2009068275A3
Authority
WO
WIPO (PCT)
Prior art keywords
amino acid
acid derivatives
improving solubility
solubility
improving
Prior art date
Application number
PCT/EP2008/010045
Other languages
English (en)
French (fr)
Other versions
WO2009068275A2 (de
Inventor
Thomas Rudolph
Herwig Buchholz
Michaela Klante
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Priority to JP2010535285A priority Critical patent/JP2011504891A/ja
Priority to US12/745,143 priority patent/US8293784B2/en
Priority to EP08853958A priority patent/EP2211827A2/de
Publication of WO2009068275A2 publication Critical patent/WO2009068275A2/de
Publication of WO2009068275A3 publication Critical patent/WO2009068275A3/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216—Solid or semisolid forms
    • A61K8/022—Powders; Compacted Powders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/26—Optical properties
    • A61K2800/262—Transparent; Translucent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30—Characterized by the absence of a particular group of ingredients
    • A61K2800/31—Anhydrous

Abstract

Die Erfindung betrifft die Verwendung von α-Aminosäurederivaten zur Löslichkeitsverbesserung von schwerlöslichen Substanzen in Wasser oder wässrigen Lösungen, sowie Mischungen und bevorzugte Zubereitungen.
PCT/EP2008/010045 2007-11-29 2008-11-27 α-AMINOSÄUREDERIVATE ZUR LÖSLICHKEITSVERBESSERUNG WO2009068275A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2010535285A JP2011504891A (ja) 2007-11-29 2008-11-27 溶解性を改良するためのα−アミノ酸誘導体
US12/745,143 US8293784B2 (en) 2007-11-29 2008-11-27 α-amino acid derivatives for improving solubility
EP08853958A EP2211827A2 (de) 2007-11-29 2008-11-27 Alpha-aminosäurederivate zur löslichkeitsverbesserung

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102007057543.4 2007-11-29
DE102007057543A DE102007057543A1 (de) 2007-11-29 2007-11-29 a-Aminosäurederivate zur Löslichkeitsverbesserung

Publications (2)

Publication Number Publication Date
WO2009068275A2 WO2009068275A2 (de) 2009-06-04
WO2009068275A3 true WO2009068275A3 (de) 2010-09-23

Family

ID=40377294

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/010045 WO2009068275A2 (de) 2007-11-29 2008-11-27 α-AMINOSÄUREDERIVATE ZUR LÖSLICHKEITSVERBESSERUNG

Country Status (5)

Country Link
US (1) US8293784B2 (de)
EP (1) EP2211827A2 (de)
JP (1) JP2011504891A (de)
DE (1) DE102007057543A1 (de)
WO (1) WO2009068275A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6295261B2 (ja) * 2012-10-12 2018-03-14 ロレアル 少なくとも一種のヒドロトロープ及び少なくとも一種の活性化合物を含む化粧品組成物
CN105963244A (zh) * 2016-01-15 2016-09-28 赵鸣 注射用青蒿琥酯制剂及其应用
JP7194517B2 (ja) * 2017-05-30 2022-12-22 花王株式会社 皮膚化粧料
CN110785161B (zh) 2017-06-23 2023-06-20 宝洁公司 用于改善皮肤外观的组合物和方法
KR20210011964A (ko) 2018-07-03 2021-02-02 더 프록터 앤드 갬블 캄파니 피부 병태를 치료하는 방법
US10959933B1 (en) 2020-06-01 2021-03-30 The Procter & Gamble Company Low pH skin care composition and methods of using the same
JP2023528616A (ja) 2020-06-01 2023-07-05 ザ プロクター アンド ギャンブル カンパニー ビタミンｂ３化合物の皮膚への浸透を改善する方法

Citations (8)

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Publication number Priority date Publication date Assignee Title
US4980165A (en) * 1989-01-27 1990-12-25 Genetics Institute, Inc. Pharmaceutical formulations of plasminogen activator proteins
CH685561A5 (de) * 1992-01-27 1995-08-15 Polygon Chemie Ag Verwendung von von beta-Alanin und dessen Homologen abgeleiteten Tensiden zur Verbesserung der Wasserlöslichkeit von Farbstoffen und optischen Aufhellern.
US20030114324A1 (en) * 2001-12-14 2003-06-19 Rainer Lange Cleansing compositions and their use in feminine hygiene wipes
US20040043940A1 (en) * 2000-03-24 2004-03-04 Buenger Joachim Use of ectoin or ectoin derivatives for protecting stress proteins in the skin
EP1407758A1 (de) * 2002-10-10 2004-04-14 Beiersdorf AG Fettfreie Sonnenschutzmittel
US20060029563A1 (en) * 2002-12-30 2006-02-09 Jean-Noel Thorel Cutanceous metabolic bio-activator
US20070027223A1 (en) * 2005-07-28 2007-02-01 Werner Bruchert Foamed preparation
US20070155695A1 (en) * 2004-01-19 2007-07-05 Corinna Wirth Flavonoid complexes with cyclodextrins

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DE4116123B4 (de) 1991-05-17 2006-03-09 Merck Patent Gmbh Mittel zur Behandlung von Hauterkrankungen
JPH05301813A (ja) * 1991-10-15 1993-11-16 Kao Corp 皮膚外用剤
DE4308282C2 (de) 1993-03-16 1994-12-22 Beiersdorf Ag Vorzugsweise in Form von Mikrosphärulen vorliegende galenische Matrices
FR2755856B1 (fr) 1996-11-21 1999-01-29 Merck Clevenot Laboratoires Microcapsules de chitine ou de derives de chitine contenant une substance hydrophobe, notamment un filtre solaire et procede de preparation de telles microcapsules
CN1293565A (zh) * 1998-03-16 2001-05-02 宝洁公司 调节皮肤外观的组合物
ATE546131T1 (de) 1998-08-13 2012-03-15 Sol Gel Technologies Ltd Verfahren zur herstellung von mit funktionalisierten molekülen beladene oxid- mikrokapseln und die daraus erhaltenen produkte
US6238650B1 (en) 1999-05-26 2001-05-29 Sol-Gel Technologies Ltd. Sunscreen composition containing sol-gel microcapsules
US6436375B1 (en) 1999-05-25 2002-08-20 Sol-Gel Technologies Ltd. Method for obtaining photostable sunscreen compositions
DE60231272D1 (de) * 2001-06-26 2009-04-09 Oreal Zusammensetzungen, die eine wenig lösliche Verbindung und ein lipophiles Aminosäurederivat enthalten, und entsprechende Verwendungen und Verfahren
DE10133202A1 (de) 2001-07-07 2003-01-16 Beiersdorf Ag Osmolyte enthaltende kosmetische und dermatologische Zubereitungen zur Behandlung und aktiven Prävention trockener Haut und anderer negativer Veränderungen der physiologischen Homöostase der gesunden Haut
DE10232595A1 (de) 2002-07-18 2004-02-05 Merck Patent Gmbh Lichtschutzmittel
DE10240923A1 (de) * 2002-09-02 2004-03-04 Merck Patent Gmbh Flavonoid-Derivate zur Ekzem-Behandlung
DE10244282A1 (de) 2002-09-23 2004-04-01 Merck Patent Gmbh Zubereitung mit antioxidanten Eigenschaften
DE10316666B4 (de) * 2003-04-10 2015-04-09 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen mit einer Kombination von Kreatinin mit Kreatin und Coenzym Q10
JP5241054B2 (ja) * 2004-02-27 2013-07-17 ロート製薬株式会社 コラーゲン合成促進用組成物
JP2005298452A (ja) * 2004-04-16 2005-10-27 Saga Seiyaku Kk アズレン誘導体含有の水性液剤の安定化法
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Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980165A (en) * 1989-01-27 1990-12-25 Genetics Institute, Inc. Pharmaceutical formulations of plasminogen activator proteins
CH685561A5 (de) * 1992-01-27 1995-08-15 Polygon Chemie Ag Verwendung von von beta-Alanin und dessen Homologen abgeleiteten Tensiden zur Verbesserung der Wasserlöslichkeit von Farbstoffen und optischen Aufhellern.
US20040043940A1 (en) * 2000-03-24 2004-03-04 Buenger Joachim Use of ectoin or ectoin derivatives for protecting stress proteins in the skin
US20030114324A1 (en) * 2001-12-14 2003-06-19 Rainer Lange Cleansing compositions and their use in feminine hygiene wipes
EP1407758A1 (de) * 2002-10-10 2004-04-14 Beiersdorf AG Fettfreie Sonnenschutzmittel
US20060029563A1 (en) * 2002-12-30 2006-02-09 Jean-Noel Thorel Cutanceous metabolic bio-activator
US20070155695A1 (en) * 2004-01-19 2007-07-05 Corinna Wirth Flavonoid complexes with cyclodextrins
US20070027223A1 (en) * 2005-07-28 2007-02-01 Werner Bruchert Foamed preparation

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Also Published As

Publication number Publication date
US8293784B2 (en) 2012-10-23
DE102007057543A1 (de) 2009-06-04
US20110039924A1 (en) 2011-02-17
JP2011504891A (ja) 2011-02-17
EP2211827A2 (de) 2010-08-04
WO2009068275A2 (de) 2009-06-04

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