WO2002015873A2

WO2002015873A2 - Personal care compositions containing adhesive elastomeric polymer and inorganic colloid

Info

Publication number: WO2002015873A2
Application number: PCT/US2001/026233
Authority: WO
Inventors: Ali Abdelaziz Alwattari
Original assignee: The Procter & Gamble Company
Priority date: 2000-08-22
Filing date: 2001-08-22
Publication date: 2002-02-28
Also published as: WO2002015873A3; WO2002015873A8; AU2001285201A1

Abstract

The present invention relates to skin care compositions containing a film-forming inorganic colloid and an adhesive elastomeric polymer and to methods of using such compositions to regulate the appearance of skin and/or hair. The compositions contain from about 0.1 % to about 60 % of a film-forming inorganic colloid, from about 0.1 % to about 70 % of an adhesive elastomeric polymer, and from about 10 % to about 99.8 % of a dermatologically acceptable carrier.

Description

PERSONAL CARE COMPOSITIONS

CONTAINING ADHESIVE ELASTOMERIC POLYMER

AND INORGANIC COLLOID

TECHNICAL FIELD

The present invention relates to topical personal care compositions containing inorganic colloids and adhesive elastomeric polymers and to methods of use thereof. Such compositions are useful for modifying the visible appearance of skin and/or hair, especially for regulating visible and/or tactile discontinuities in skin associated, e.g., with skin aging.

BACKGROUND

Many personal care products currently available to consumers are directed primarily to improving the health and/or physical appearance of the skin and/or hair. Among the skin care products, many are directed to delaying, minimizing or even eliminating skin wrinkling and other histological changes typically associated with the aging of skin or environmental damage to human skin. Numerous compounds have been described in the art as being useful for regulating skin condition, including regulating fine lines, wrinkles and other forms of uneven or rough surface texture associated with aged or photodamaged skin.

Skin and hair are subject to insults by many extrinsic and intrinsic factors. Extrinsic factors include ultraviolet radiation (e.g., from sun exposure), environmental pollution, wind, heat, low humidity, harsh surfactants, abrasives, and the like. Intrinsic factors include chronological aging and other biochemical changes from within the skin and/or hair follicle. Whether extrinsic or intrinsic, these factors result in visible signs of skin aging and environmental damage, such as wrinkling and other forms of roughness (including increased pore size, flaking and skin lines), and other histological changes associated with skin aging or damage. To many people, skin wrinkles are a reminder of the disappearance of youth. As a result, the elimination of wrinkles has become a booming business in youth-conscious societies. Treatments range from cosmetic creams and moisturizers to various forms of cosmetic surgery.

Extrinsic or intrinsic factors may result in the thinning and general degradation of the skin. For example, as the skin naturally ages, there is a reduction in the cells and blood vessels that supply the skin. There is also a flattening of the dermal-epidermal junction which results in weaker mechanical resistance of this junction. See, for example, Oikarinen, "The Aging of Skin: Chronoaging Versus Photoaging," Photodermatol. Photoimmunol. Photomed., vol. 7, pp. 3-4, 1990, which is incorporated by reference herein in its entirety. A large number of skin care actives are known in the art and used to improve the health and/or physical appearance of the skin. For example, salicylic acid and benzoyl peroxide are used in skin care compositions to treat acne. Retinol and other retinoids are known for use in skin care compositions to reduce signs of aging skin. Although formulating skin care compositions with such actives provide skin care benefits, there is often a significant lag time between when the product is applied and when visible results are perceived by the consumer. This lag time can lead to consumer frustration and discontinuation of product use.

Products directed to using stress (for example, created by a film on the skin) to smooth facial wrinkles currently exist on the marketplace. For example, a wrinkle-smoothing product is currently available which contains the anionic polymers sodium dextran sulphate and bovine serum albumin. Products such as this do provide a limited reduction of the appearance of wrinkles when applied to the skin. However, some of these products are generally brittle, glassy, and/or water-sensitive when applied to the surface of the skin. Due to these properties, as soon as the consumer moves their facial muscles (such as to blink or smile), the product fractures. The fracturing can cause many disadvantages, including loss of the wrinkle reduction benefit, and often also causes a highly undesirable visible whiteness or other negative aesthetic. Several hours after application, the visual appearance of facial wrinkles can often be worse than before the application of product as a result of, for example, unsightly peeling, fracture and/or whiteness of the material. Perspiration and humidity also may cause a degradation of any original application benefit.

Based on the foregoing, there is a continuing need to formulate skin care compositions which improve the physical appearance of the skin, which are effective in providing an immediate visually perceived benefit in the physical appearance of skin. For example, without fracturing or peeling from the skin.

SUMMARY

The present invention relates to a composition containing from about 0.1% to about 60%, by weight of the composition of an inorganic colloid having a Tg of greater than 25°C; from about 0.1% to about 70%, by weight of the composition, of an adhesive elastomeric polymer having a Tg of less than 40°C; and a dermatologically acceptable carrier.

The present invention also relates to methods of using such compositions to modify the appearance of skin and/or hair. Said methods generally contain the step of topically applying (either together or in sequence) a safe and effective amount of the individual elements of the composition to the skin and/or hair of a mammal needing such treatment. The present invention also relates to methods of using such compositions to style hair, especially human facial hair (e.g. eyebrows, eyelashes). Such methods generally contain the step of topically applying to the hair of a mammal in need of treatment, a safe and effective amount of such compositions.

The present invention also relates to a personal care kit useful for modifying the appearance of skin or hair containing an inorganic colloid having a Tg greater than 25°C and an adhesive elastomeric polymer having a Tg of less than 40°C.

These and other features, aspects, and advantages of the present invention will become evident to those skilled in the art from a reading of the present disclosure.

DETAILED DESCRIPTION

While the specification concludes with the claims particularly pointing and distinctly claiming the invention, it is believed that the present invention will be better understood from the following description.

All percentages and ratios used herein are by weight of the total composition and all measurements made are at 25 C, unless otherwise designated.

The compositions of the present invention can comprise, consist essentially of, or consist of, the components of the present invention as well as other ingredients described herein. As used herein, "consisting essentially of means that the composition or component may include additional ingredients, but only if the additional ingredients do not materially alter the basic and novel characteristics of the claimed compositions or methods.

All publications cited herein are hereby incorporated by reference in their entirety.

The term "keratinous tissue," as used herein, refers to keratin-containing layers disposed as the outermost protective covering of mammals (e.g., humans, dogs, cats, etc.) which includes, but is not limited to, skin, lips, hair, toenails, fingernails, cuticles, hooves, etc.

The term "dermatologically-acceptable," as used herein, means that the compositions or components thereof so described are suitable for use in contact with mammalian keratinous tissue without undue toxicity, incompatibility, instability, allergic response, and the like.

The term "safe and effective amount" as used herein means an amount of a compound or composition sufficient to significantly induce a positive benefit, preferably a positive keratinous tissue appearance or feel benefit, or positive hair appearance or feel benefit, including independently or in combinations the benefits disclosed herein, but low enough to avoid serious side effects, i.e., to provide a reasonable benefit to risk ratio, within the scope of sound judgment of the skilled artisan. The term "sagging" as used herein means the laxity, slackness, or the like condition of skin that occurs as a result of loss of, damage to, alterations to, and/or abnormalities in dermal elastin.

The terms "smoothing" and "softening" as used herein mean altering the surface of the keratinous tissue such that its tactile feel is improved.

"Signs of skin aging" include, but are not limited to, all outward visibly and tactilely perceptible manifestations as well as any other macro or micro effects due to skin aging. Such signs may be induced or caused by intrinsic factors or extrinsic factors, e.g., chronological aging and/or environmental damage. These signs may result from processes which include, but are not limited to, the development of textural discontinuities such as wrinkles and coarse deep wrinkles, skin lines, crevices, bumps, large pores (e.g., associated with adnexal structures such as sweat gland ducts, sebaceous glands, or hair follicles), or unevenness or roughness, loss of skin elasticity (loss and/or inactivation of functional skin elastin), sagging (including puffiness in the eye area and jowls), loss of skin firmness, loss of skin tightness, loss of skin recoil from deformation, discoloration (including undereye circles), blotching, sallowness, hyperpigmented skin regions such as age spots and freckles, keratoses, abnormal differentiation, hyperkeratinization, elastosis, collagen breakdown, and other histological changes in the stratum corneum, dermis, epidermis, the skin vascular system (e.g., telangiectasia or spider vessels), and underlying tissues, especially those proximate to the skin.

As discussed above, products containing polymers and directed to smoothing facial wrinkles currently exist on the marketplace. However, upon application and subsequent drying on the skin, some of these products generally become brittle, glassy, and/or water-sensitive. Because of these properties, the products often result in disadvantages such as an undesirable visible whiteness. A need therefore exists to foπnulate skin care compositions which improve the physical appearance of the skin and which are effective in providing an immediate visually perceived benefit in the physical appearance of skin such as, for example, without fracturing or peeling of the product from the skin.

Surprisingly, it has now been found that compositions containing a combination of a film- forming inorganic colloid having a Tg of greater than 25°C and an adhesive elastomeric polymer having a Tg of less than 40°C, provide substantially immediate visual benefits in regulating skin condition and styling hair previously unrecognized in the art of which the present inventors are aware. For example, topical applications of a film-forming inorganic colloid and an adhesive elastomeric polymer provide controlled delivery of physical stress on the skin or hair while simultaneously accomplishing adhesion and flexibility such that the effect is both acute and sustained, for example, over time, such as over the course of the daytime (8 hours). For example, when applied to skin, topical applications of the film-forming inorganic colloid and adhesive elastomeric polymer can provide a texture and firming effect, while when applied to hair, the effect is a styling advantage (e.g. smoothing hair, curling eyelashes). Additionally, the effect of applying film-forming inorganic colloid and adhesive polymer to the skin can work for virtually all visible skin texture discontinuities (e.g. wrinkles, fine lines, under eye bags and dark circles, sagging skin, scars/marks, dimples, pores, stretch marks, roughness, skin surface, frown lines, expression lines, rhytides, blemishes, photodamage, crevices, and unevenness). Without being limited by theory, it is believed that the adhesive elastomeric polymer protects the inorganic colloid film from fracturing or otherwise breaking, and adheres the inorganic colloid to the skin or hair. It is also believed that the texture reduction (e.g. wrinkle smoothing and/or hair styling effect is a result of the inorganic colloid film coating the skin or hair and the physical stress creation caused by the drying of the polymer mixture.

Generally, the compositions herein are applied to the skin and/or hair and allowed to dry. For example, when applied to the skin, as the composition dries, stress is created on the skin, causing the wrinkled skin (or other discontinuity) to be pulled flat and thereby appear diminished. Also for example, when applied to the hair, as the composition dries, stress is created on the hair shaft causing a curling or styling effect. The effect on hair can, for example, result in the curling of eyelashes, especially when applied as part of a mascara cosmetic application.

None of the existing art provides all of the advantages and benefits of the present invention.

The compositions of the present invention are also useful for physically regulating the condition of skin and especially for regulating keratinous tissue condition. Regulation of skin condition, namely mammalian and in particular human skin condition, is often required due to conditions which may be induced or caused by factors internal and/or external to the body. Examples include, environmental damage, radiation exposure (including ultraviolet radiation), chronological aging, menopausal status (e.g., post-menopausal changes in skin), stress, diseases, etc. For instance, "regulating skin condition" includes prophylactically regulating and/or therapeutically regulating skin condition, and may involve one or more of the following benefits: thickening of skin (i.e., building the epidermis and/or dermis and/or sub-dermal (e.g., subcutaneous fat or muscle) layers of the skin and where applicable the keratinous layers of the nail and hair shaft) to reduce skin atrophy, increasing the convolution of the dermal-epidermal border (also known as the rete ridges), preventing loss of skin elasticity (loss, damage and/or inactivation of functional skin elastin) such as elastosis, sagging, loss of skin recoil from deformation; non-melanin skin discoloration such as under eye circles, blotching (e.g., uneven red coloration due to, e.g., rosacea) (hereinafter referred to as "red blotchiness"), sallowness (pale color), discoloration caused by telangiectasia or spider vessels.

As used herein, prophylactically regulating skin condition includes delaying, minimizing and/or preventing visible and/or tactile discontinuities in skin (e.g., texture irregularities in the skin which may be detected visually or by feel).

As used herein, therapeutically regulating skin condition includes ameliorating, e.g., diminishing, minimizing and/or effacing, discontinuities in skin.

The compositions of the present invention are also useful for improving skin appearance and/or feel. For example, compositions of the present invention are useful for regulating the appearance of skin condition by providing an immediate visual improvement in skin appearance following application of the composition to the skin. The compositions of the present invention are also useful for styling hair. For example, the compositions of the present invention are useful for curling hair, especially eyelashes.

The compositions of the present invention contain a film-forming inorganic colloid having a Tg of greater than 25 °C, an adhesive elastomeric polymer having a Tg of less than 40°C, and a dermatologically acceptable carrier. The compositions herein may also include a wide variety of other ingredients.

The compositions of the present invention, are described in detail hereinafter.

I. Inorganic Colloid

The compositions of the present invention include from about 0.1% to about 60%, by weight of the composition, of an inorganic film-forming colloid having a Tg of greater than 25°C.

The term "glass transition" or "Tg" is a known term of art in polymer science used to describe the temperature at which a polymer or portion thereof undergoes a transition from a solid or brittle material to a liquid or rubber-like material. Glass transition temperatures can be measured using standard techniques that are well known to the polymer scientist of ordinary skill in the art. One useful technique for determining glass transitions is differential scanning calorimetry (also known as DSC). A differential scanning calorimeter, measures a change in enthalpy with a change in time, dH/dt, as a function of programmed temperature T. The glass transition phenomenon in polymers is described in Polymer Handbook, Third Edition (eds. J. Brandrup and E. H. Immergut), (John Wiley & Sons, Inc.: 1989), which is incorporated by reference herein in its entirety. By "film-forming" as used herein is meant that the dispersed inorganic colloid is capable of forming a film when spread onto glass and allowed to dry at ambient temperature. Preferably, the inorganic colloid is capable of forming a continuous film when dried on glass.

The preferred inorganic film-forming colloid may be selected from silica, boehmite alumina, zirconium dioxide, zirconium polyanions, boron nitride, nickel hydroxide, nickel acetate, zinc hydroxide, titanium dioxide and mixtures thereof. An even more preferred inorganic film- forming colloid for use herein is silica.

Preferably, the inorganic colloid is in the form of a sol. By "sol," as used herein is meant a dispersion of the inorganic colloid material in a polar solvent. In general, "polar solvent" refers to those solvents that contain hydroxyl and/or carbonyl groups and also have high dielectric constants and strong polarity.

Preferably, the inorganic colloid is negatively charged and has a particle size of less than 50 nm and a surface area of greater than 100 m²/g. Preferably the inorganic colloid has a Tg of from 25°C to about 1200°C, more preferably from about 50°C to about 900°C.

Inorganic colloids useful herein include metal compounds (e.g. zinc, titanium, silicon, aluminum) with aquo ligands (OH₂-) or hydroxy ligands (OH) or oxo ligands (=0). Examples of such compounds include colloidal silica such as Si0₂, commercially available as NALCO 1034A silica, NALCO 1115 silica, LUDOX, and SNOWTEX, from Nalco Chemical. Examples also include colloidal beohmite/alumina such as A1₂0₃ commerically available as ALUMINA SOL 520. Examples also include colloidal zirconium dioxide sol Zr0₂ or polyanions like Zr(HP0 )₂. Examples further include colloidal sol of boron nitride; colloidal nickel hydroxide or Ni(OAc)₂ sols.

II. Adhesive Elastomeric Polymer

The compositions of the present invention include from about 0.1% to about 70%, preferably from about 0.5% to about 65%, more preferably from about 1% to about 60%, and even more preferably from about 4% to about 55%, by weight of the composition, of an adhesive elastomeric polymer having a Tg value of less than 40°C.

By "elastomeric" is meant that the polymer has an elastic modulus such that the copolymer exhibits a resistance to deformation and has limited extensibility and retraction. Preferably, the polymer generally may be stretched to at least 30% of the original length and return to approximately the original length when released. By "adhesive" is meant that when applied as a solution to a surface and dried, e.g., the skin, the polymer adheres to the skin. Preferably, upon drying, the polymer adheres to the skin or hair. More preferably, the polymer forms films or welds on the skin.

Preferably, the adhesive elastomeric polymers used herein have a Tg of from about -50°C to 40°C, more preferably from about -70°C to about 10°C.

Examples of adhesive elastomeric polymers useful herein include oil soluble elastomers, latexes, polar solvent soluble elastomers, and mixtures thereof. Suitable adhesive elastomeric polymers are more fully discussed below.

Oil Soluble Elastomers

Suitable oil-soluble adhesive elastomeric polymers for use herein include linear copolymers, branched copolymers, random copolymers, block copolymers, di-block copolymers, tri-block copolymers, multi-block copolymers, grafted copolymers, and/or star-shaped copolymers of the following: styrene-isoprene elastomers, styrene-butadiene elastomers, styrene- ethylene/propylene-styrene elastomers, styrene-ethylene butylene-styrene elastomers, terminal hydroxylated polyethylene/butylene elastomers, ethylene-propylene elastomers, random thermoplastic elastomers, polystyrene-co-polyethylenepropylene elastomers, and mixtures thereof.

Additionally, grafted copolymers in the above list may also be used in the present invention. For example, grafts (such as t-butyl styrene) onto the polymers listed above may be used in the present invention.

Preferred are the oil-soluble adhesive elastomeric copolymers selected from styrene- isoprene linear copolymers, styrene-isoprene branched copolymers, styrene-isoprene di-block, tri- block, or star shaped copolymers, and mixtures thereof.

Examples of commercially available oil-soluble adhesive elastomeric polymers include styrene-isoprene copoloymer elastomers such as KRATON LVSI-101 and KRATON D2224P, styrene-butadiene elastomers such as KRATON D, styrene-ethylene/propylene-styrene or styrene- ethylene/butylene-styrene elastomers such as KRATON G and KRATON FG1901X, terminal hydroxylated polyethylene/butylene elastomers such as KRATON L-2203 and KRATON L1203, all available from the Shell Oil Company.

Examples of commercially available oil-soluble adhesive elastomeric polymers include branched di-block or tri-block or star-shaped copolymer elastomers of ethylene-propylene such as KRATON D1116, KRATON D1124, KRATON G1750X, KRATON G1765X, all available from the Shell Oil Company. Latexes

Examples of latexes useful herein include styrene-acrylate elastomer latex, silicone elastomer latex, acrylic acid ester elastomer latex, and styrene-butadiene elastomer latex.

An example of styrene-acrylate elastomer latexes include those sold under the name HYSTRETCH available from B. F. Goodrich.

Silicone elastomer latexes useful herein include DC74166 available from Dow Corning.

Acrylic acid ester elastomer latexes useful herein include GELVA 2333 available from Monsanto and HYCAR available from B. F Goodrich..

Syrene-butadiene elastomer latexes useful herein include GOODRITE available from B. F. Goodrich.

Polar Solvent Soluble Elastomers

Polar solvent soluble elastomers for use herein include thermoplastic block elastomers, crosslinked polyvinylalcohol, and peo-co-vinyl alcohol.

HI. Dermatologically-Acceptable Carrier

The topical compositions of the present invention also include from about 10% to about 99.8%, by weight of the composition, of a dermatologically acceptable carrier for the inorganic colloid and the adhesive elastomeric polymer. The phrase "dermatologically-acceptable carrier", as used herein, means that the carrier is suitable for topical application to the keratinous tissue, has good aesthetic properties, is compatible with the actives of the present invention and any other components, and will not cause any untoward safety or toxicity concerns. Preferably, the composition includes from about 30% to about 80%, more preferably from about 40% to about 80%, by weight of the composition, of the dermatologically acceptable carrier.

Examples of suitable dermatologically acceptable carriers for use herein include volatile organic solvents, water, polar solvents, ketones, aromatic hydrocarbons, aliphatic hydrocarbons, silicone solvents, aliphatic alcohols, diacetone alcohol, esters, alcohols, glycols, glycol ethers, aromatics. A preferred carrier is water. Mixtures of dermatologically acceptable carriers may be used herein. Preferred mixtures include water and alcohol; water and aliphatic hydrocarbons.

Examples of aliphatic hydrocarbons useful herein include isododecane and isopropylmyristate. Examples of silicone solvents useful herein include cyclomethicone, dimethiconol, and dimethicone. Examples of ketones useful herein include hexane/methyl ethyl ketone blends and methyl isobutyl ketone. Examples of alcohols useful herein include isopropyl alcohol and those with similar properties. Examples of volatile organic solvents useful herein include hydrocarbon oils, silicone oils, and mixtures thereof. A preferred volatile carrier is isododecane.

The carrier can be in a wide variety of forms. For example, emulsion carriers, including, but not limited to, oil-in-water, water-in-oil, water-in-silicone, water-in-oil-in-water, microemulsions, propellants, and oil-in-water-in-silicone emulsions, are useful herein. The carrier may also be a tonic, serum, or gel. As will be understood by the skilled artisan, a given component will distribute primarily into either the water or oil/silicone phase, depending on the water solubility/dispersibility of the component in the composition. Microemulsion forms are especially preferred.

Emulsifiers may also be used in the emulsion forms of the present invention. Suitable emulsifiers are disclosed in, for example, U.S. Patent 3,755,560, issued August 28, 1973, Dickert et al.; U.S. Patent 4,421,769, issued December 20, 1983, Dixon et al.; and McCutcheon's Detergents and Emulsifiers. North American Edition, pages 317-324 (1986).

Surfactants such as nonionic and anionic surfactants such as are known in the art are also useful herein. See, e.g., McCutcheon's, Detergents and Emulsifiers. North American Edition (1986), published by Allured Publishing Corporation and incorporated herein by reference. The surfactants useful herein can contain a single surfactant, or any combination of suitable surfactants. Product Forms

The topical compositions of the subject invention, including but not limited to lotions and creams, may contain a dermatologically acceptable emollient. Such compositions preferably contain from about 1% to about 50% of the emollient. As used herein, "emollient" refers to a material useful for the prevention or relief of dryness, as well as for the protection of the skin. A wide variety of suitable emollients are known and may be used herein. Sagarin, Cosmetics. Science and Technology. 2nd Edition, Vol. 1, pp. 32-43 (1972), incorporated herein by reference, contains numerous examples of materials suitable as an emollient. A preferred emollient is glycerin. Glycerin is preferably used in an amount of from or about 0.001 to or about 30%, more preferably from or about 0.01 to or about 20%, still more preferably from or about 0.1 to or about 10%.

The compositions of the present invention, in some embodiments, may be formulated as a cosmetic foundation. As used herein, the term "foundation" refers to a liquid, semi-liquid, semi- solid, or solid skin cosmetic which includes, but is not limited to lotions, creams, gels, pastes, cakes, and the like. Typically the foundation can either be used over a large area of the skin, such as over the face, or may be applied to specific areas to hide skin imperfections and impart a smooth, even appearance to the skin. Foundations of the present invention may include conventional ingredients such as oils, colorants, pigments, emollients, fragrances, stabilizers, and the like. Stress Creation Material

The compositions of the present invention, in some embodiments, may further contain an additional physical stress creating material (in addition to the inorganic colloid discussed above) that is useful for providing additional physical stress to the skin in order to further regulate the appearance of skin wrinkles. Preferred for use herein are oil-soluble film-forming polymers and ionic film-forming polymers, discussed below.

Oil-Soluble Film-Forming Polymers

The topical compositions of the present invention may, in some embodiments, further include from about 0.1% to about 60%, preferably from about 1% to about 50%, more preferably from about 3% to about 40%, even more preferably from about 5% to about 25%, by weight of the composition, of an oil-soluble, film-forming polymer having a Tg of greater than 25°C.

Preferably, the oil-soluble film-forming polymers have a Tg of from about 25°C to about 750°C, more preferably from about 50°C to about 600°C.

Examples of oil-soluble film-forming polymers useful herein include alkyds, shellacs, polystyrene, organosiloxane resins, and mixtures thereof.

Preferred oil-soluble film-forming polymers for use herein include film-forming organosiloxane resins having a Tg of greater than 25°C. The organosilioxane resins contain ^R3^si0l/2 "^M" ^units> R2^si0 "^D" ^units> ^RSi03/2 "^τ" ^units> ^{and or si0}2 "Q" ^units- Preferably, the "M", "D", "T", and/or "Q" units are selected to satisfy the relationship

where n is a value between 1.0 and 1.50 and R is a Ci to Cι₂ lower alkyl group. Preferably, R is a methyl group. A small amount, up to 5%, of silanol or alkoxy functionality may also be present in the resin structure as a result of processing. Preferably, the resin is soluble in organic solvents such as toluene, xylene, isoparaffϊns, and cyclosiloxanes or the volatile carrier, indicating that the resin is not tightly crosslinked. Particularly preferred are resins comprising repeating monofunctional or R3Siθ /2 "M" units and the quadrafunctional or Siθ2 "Q" units, otherwise known as "MQ" resins.

Commercially available organosiloxane resins useful herein include Wacker MQ (Wacker-Belsil TMS) and WACKER MT resins available from Wacker Silicones Corporation of Adrian, Michigan; GE MQ (including GE SRI 000 and SS4267) from the General Electric Company; and DOW CORNING MQ, (DC593) available from Dow Corning. A preferred oil-soluble film-forming polymer for use herein is poly(trimethylsiloxysilicate) .

Ionic Film-Forming Polymers

The topical compositions of the present invention may, in some embodiments, further include from about 0.1% to about 70%, preferably from about 1%> to about 50%, more preferably from about 3% to about 40%, even more preferably from about 5% to about 25%, by weight of the composition, of an ionic, film-forming polymer having a Tg of greater than 25°C.

Preferably, the ionic film-forming polymers have a negative charge density of at least one negative charge per every ten repeating units of polymer, more preferably one negative charge per every two repeating units of polymer, even more preferably one negative charge per repeating unit of polymer. Preferred are ionic film-forming polymers having a Tg of from 25°C to about 300°C, more preferably from about 50°C to about 200°C.

Examples of ionic film-forming polymers useful herein include the anionic film-forming polymers sodium polystyrene sulfonate, sodium silicone t-butyl acrylate, sodium poly(styrene sulfonate/maleic anhydride), sodium poly(styrene sulfonate co acrylein), polyvinylsulfonate, polyvinyl sulfate, polyphosphate, polymethacrylate, sodium dextran sulphate, poly(ethylene oxide co styrene sulfonate), and mixtures thereof. Also useful herein are the hydrophobically modified derivatives and polyampholytes of sodium polystyrene sulfonate, sodium silicone t-butyl acrylate, sodium poly(styrene sulfonate/maleic anhydride), sodium poly(styrene sulfonate co acrylein), polyvinylsulfonate, polyvinyl sulfate, polyphosphate, polymethacrylate, sodium dextran sulphate, poly(ethylene oxide co styrene sulfonate), and mixtures thereof.. A preferred anionic, film- forming polymer for use herein is sodium polystyrene sulfonate.

By "hydrophobically modified" is meant that hydrophobic regions are attached off the main chain of the polymer in order to make the polymer net more hydrophobic. Such modification is within the skill of one in the art.

By "polyampholytes" is meant that the polymer contains both ionic groups off the main chain as well as surfactant-like groups off the main chain. An example of polyampholytes useful herein includes poly(acrylamide-co-styrene sulfonate).

Other examples of ionic film-forming polymers useful herein include cationic film- forming polymers having a charge density of at least one negative charge per every repeating units, more preferably at least one negative charge per repeating unit. Preferred are those cationic film-forming polymers having a water insoluble backbone. A preferred cationic film-forming polymer for use herein is chitosan lactate. Commercially available ionic film-forming polymers useful herein include the FLEXAN and VERSAFLEX series of sodium polystyrene sulfonates available from National Starch.

Optional Skin Care Actives

The compositions of the present invention may, in some embodiments, contain one or more additional skin care actives.

In a preferred embodiment, where the composition is to be in contact with human keratinous tissue, the additional components should be suitable for application to keratinous tissue, that is, when incorporated into the composition they are suitable for use in contact with human keratinous tissue without undue toxicity, incompatibility, instability, allergic response, and the like within the scope of sound medical judgment. The CTFA Cosmetic Ingredient Handbook, Second Edition (1992) describes a wide variety of nonlimiting cosmetic and pharmaceutical ingredients commonly used in the skin care industry, which are suitable for use in the compositions of the present invention. Examples of these ingredient classes include: abrasives, absorbents, aesthetic components such as fragrances, pigments, colorings/colorants, essential oils, skin sensates, astringents, etc. (e.g., clove oil, menthol, camphor, eucalyptus oil, eugenol, menthyl lactate, witch hazel distillate), anti-acne agents, anti-caking agents, antifoaming agents, antimicrobial agents (e.g., iodopropyl butylcarbamate), antioxidants, binders, biological additives, buffering agents, bulking agents, chemical additives, colorants, cosmetic astringents, cosmetic biocides, denaturants, drug astringents, external analgesics, opacifying agents, pH adjusters, propellants, reducing agents, sequestrants, skin bleaching and lightening agents (e.g., hydroquinone and ascorbyl glucosamine), skin-conditioning agents (e.g., humectants, including miscellaneous and occlusive), skin soothing and/or healing agents (e.g., panthenol and derivatives (e.g., ethyl panthenol), aloe vera, pantothenic acid and its derivatives, allantoin, bisabolol, and dipotassium glycyrrhizinate), skin treating agents, thickeners, and vitamins and derivatives thereof.

In any embodiment of the present invention, however, the actives useful herein can be categorized by the benefit they provide or by their postulated mode of action. However, it is to be understood that the actives useful herein can in some instances provide more than one benefit or operate via more than one mode of action. Therefore, classifications herein are made for the sake of convenience and are not intended to limit the active to that particular application or applications listed. Phytantriol

The topical compositions of the present invention may, in some embodiments, contain a safe and effective amount of phytantriol. Phytantriol is the common name for the chemical known as 3,7,1 l,15,tetramethylhexadecane-l,2,3,-triol. Phytantriol is commercially available from BASF (1609 Biddle Avenue, Whyandotte, MI). For example, phytantriol is useful as a spider vessel/ red blotchiness repair agent, a dark circle/puffy eye repair agent, sallowness repair agent, a sagging repair agent, an anti-itch agent, a skin thickening agent, a pore reduction agent, oil/shine reduction agent, a post-inflammatory hyperpigmentation repair agent, wound treating agent, an anti-cellulite agent, and regulating skin texture, including wrinkles and fine lines.

When included in compositions of the present invention, the phytantriol preferably is included in an amount from about 0.001% to about 50% by weight of the composition, more preferably from about 0.01% to about 20%, even more preferably from about 0.1%> to about 15%, even more preferably from about 0.2% to about 10%, still more preferably from about 0.5% to about 10%, and still more preferably from about 1% to about 5%.

Farnesol

The topical compositions of the present invention may, in some embodiments, contain a safe and effective amount of farnesol. Farnesol is a naturally occurring substance which is believed to act as a precursor and/or intermediate in the biosynthesis of squalene and sterols, especially cholesterol. Farnesol is also involved in protein modification and regulation (e.g., farnesylation of proteins), and there is a cell nuclear receptor which is responsive to farnesol.

Chemically, farnesol is [2E,6E]-3,7,l l-trimethyl-2,6,10-dodecatrien-l-ol and as used herein "farnesol" includes isomers and tautomers of such. Farnesol is commercially available, e.g., under the names farnesol (a mixture of isomers from Dragoco, 10 Gordon Drive, Totowa, New Jersey) and trans-trans-farnesol (Sigma Chemical Company, P. O. Box 14508, St. Louis, Missouri).

When present in the compositions of the present invention, the composition preferably contains from about 0.001% to about 50%, by weight of the composition, more preferably from about 0.01% to about 20%, even more preferably from about 0.1% to about 15%, even more preferably from about 0.1% to about 10%, still more preferably from about 0.5% to about 5%, and still more preferably from about 1% to about 5% of farnesol.

Anti- Wrinkle Actives/Anti- Atrophy Actives

The compositions of the present invention may further contain a safe and effective amount of one or more anti-wrinkle actives or anti-atrophy actives. Exemplary anti-wrinkle/anti-atrophy actives suitable for use in the compositions of the present invention include sulfur-containing D and L amino acids and their derivatives and salts, particularly the N-acetyl derivatives, a preferred example of which is N-acetyl-L-cysteine; thiols, e.g. ethane thiol; hydroxy acids (e.g., alpha- hydroxy acids such as lactic acid and glycolic acid or beta-hydroxy acids such as salicylic acid and salicylic acid derivatives such as the octanoyl derivative), phytic acid, lipoic acid; lysophosphatidic acid, skin peel agents (e.g., phenol and the like), vitamin B₃ compounds and retinoids which enhance the keratinous tissue appearance benefits of the present invention, especially in regulating keratinous tissue condition, e.g., skin condition. a) Vitamin Bg Compounds

The compositions of the present invention may contain a safe and effective amount of a vitamin B3 compound. Vitamin B₃ compounds are particularly useful for regulating skin condition as described in U. S. Patent No. 5,939,082 issued August 17, 1999, incorporated herein by reference. When vitamin B₃ compounds are present in the compositions of the instant invention, the compositions preferably contain from about 0.01% to about 50%, more preferably from about 0.1% to about 10%, even more preferably from about 0.5% to about 10%, and still more preferably from about 1% to about 5%, still more preferably from about 2% to about 5%, by weight of the composition, of the vitamin B3 compound.

As used herein, "vitamin B3 compound" means a compound having the formula:

wherein R is - CONH2 (i.e., niacinamide), - COOH (i.e., nicotinic acid) or - CH2OH (i.e., nicotinyl alcohol); derivatives thereof; and salts of any of the foregoing.

Exemplary derivatives of the foregoing vitamin B3 compounds include nicotinic acid esters, including non-vasodilating esters of nicotinic acid (e.g., tocopheryl nicotinate), nicotinyl amino acids, nicotinyl alcohol esters of carboxylic acids, nicotinic acid N-oxide and niacinamide N-oxide.

Examples of suitable vitamin B3 compounds are well known in the art and are commercially available from a number of sources, e.g., the Sigma Chemical Company (St. Louis, MO); ICN Biomedicals, Inc. (Irvin, CA) and Aldrich Chemical Company (Milwaukee, WI).

The vitamin compounds may be included as the substantially pure material, or as an extract obtained by suitable physical and/or chemical isolation from natural (e.g., plant) sources. b) Retinoids

The compositions of the present invention may also contain a retinoid. As used herein, "retinoid" includes all natural and/or synthetic analogs of Vitamin A or retinol-like compounds which possess the biological activity of Vitamin A in the skin as well as the geometric isomers and stereoisomers of these compounds. The retinoid is preferably retinol, retinol esters (e.g., C2 -

C22 alkyl esters of retinol, including retinyl palmitate, retinyl acetate, retinyl propionate), retinal, and/or retinoic acid (including all-trans retinoic acid and/or 13-cis-retinoic acid), more preferably retinoids other than retinoic acid. These compounds are well known in the art and are commercially available from a number of sources, e.g., Sigma Chemical Company (St. Louis, MO), and Boerhinger Mannheim (Indianapolis, IN). Other retinoids which are useful herein are described in U.S. Patent Nos. 4,677,120, issued Jun. 30, 1987 to Parish et al.; 4,885,311, issued Dec. 5, 1989 to Parish et al.; 5,049,584, issued Sep. 17, 1991 to Purcell et al.; 5,124,356, issued Jun. 23, 1992 to Purcell et al.; and Reissue 34,075, issued Sep. 22, 1992 to Purcell et al.. Other suitable retinoids are tocopheryl-retinoate [tocopherol ester of retinoic acid (trans- or cis-), adapalene {6-[3-(l-adamantyl)-4-methoxyphenyl]-2-naphthoic acid}, and tazarotene (ethyl 6-[2- (4,4-dimethylthiochroman-6-yl)-ethynyl]nicotinate). Preferred retinoids are retinol, retinyl palmitate, retinyl acetate, retinyl propionate, retinal and combinations thereof.

The retinoid may be included as the substantially pure material, or as an extract obtained by suitable physical and/or chemical isolation from natural (e.g., plant) sources. The retinoid is preferably substantially pure, more preferably essentially pure.

The compositions of this invention may contain a safe and effective amount of the retinoid, such that the resultant composition is safe and effective for regulating keratinous tissue condition, preferably for regulating visible and/or tactile discontinuities in skin, more preferably for regulating signs of skin aging, even more preferably for regulating visible and/or tactile discontinuities in skin texture associated with skin aging. The compositions preferably contain from or about 0.005% to or about 2%, more preferably 0.01% to or about 2%>, retinoid. Retinol is preferably used in an amount of from or about 0.01% to or about 0.15%; retinol esters are preferably used in an amount of from or about 0.01% to or about 2% (e.g., about 1%); retinoic acids are preferably used in an amount of from or about 0.01% to or about 0.25%; tocopheryl- retinoate, adapalene, and tazarotene are preferably used in an amount of from or about 0.01% to or about 2%.

Where the compositions of the present invention contain both a retinoid and a Vitamin B3 compound, the retinoid is preferably used in the above amounts, and the vitamin B3 compound is preferably used in an amount of from or about 0.1% to or about 10%, more preferably from or about 2% to or about 5%. Peptides

Peptides, including but not limited to, di-, tri-, tetra-, and pentapeptides and derivatives thereof, may be included in the compositions of the present invention in amounts that are safe and effective. As used herein, "peptides" refers to both the naturally occurring peptides and synthesized peptides. Also useful herein are naturally occurring and commercially available compositions that contain peptides.

Suitable dipeptides for use herein include Carnosine® (beta-ala-his). Suitable tripeptides for use herein include, gly-his-lys, arg-lys-arg, his-gly-gly. Preferred tripeptides and derivatives thereof include palmitoyl-gly-his-lys, which may be purchased as Biopeptide CL® (lOOppm of palmitoyl-gly-his-lys commercially available from Sederma, France); Peptide CK (arg-lys-arg); PEPTIDE CK+ (ac-arg-lys-arg-NH2); and a copper derivative of his-gly-gly sold commercially as

IAMIN, from Sigma (St.Louis, Missouri). Tetrapeptides and pentapeptides are also suitable for use herein. A preferred commercially available pentapeptide derivative composition is MATRIXYL®, (commercially available from Sederma France).

When included in the present compositions, peptides are preferably included in amounts of from about lxl0^"6% to about 10%, more preferably from about lxl0^"6% to about 0.1%, even more preferably from about lxl0^"5% to about 0.01%, by weight of the composition. In certain compositions where the peptide is Carnosine®, the compositions preferably contain from about 0.1% to about 5%, by weight of the composition, of such peptides. In other embodiments wherein the peptide-containing compositions, Matrixyl®, and/or Biopeptide CL® are included, the compositions preferably contain from about 0.1% to about 10%, by weight compositions, of Matrixyl® and/or Biopeptide CL® peptide-containing compositions.

Anti-Oxidants/Radical Scavengers

The compositions of the present invention may include a safe and effective amount of an anti-oxidant/radical scavenger. The anti-oxidantradical scavenger is especially useful for providing protection against UV radiation which can cause increased scaling or texture changes in the stratum comeum and against other environmental agents which can cause skin damage.

A safe and effective amount of an anti-oxidant/radical scavenger may be added to the compositions of the subject invention, preferably from about 0.1% to about 10%, more preferably from about 1% to about 5%, of the composition.

Anti-oxidants/radical scavengers such as ascorbyl esters of fatty acids, tocopherol (vitamin E), tocopherol sorbate, tocopherol acetate, other esters of tocopherol, amines (e.g., N,N- diethylhydroxylamine, amino-guanidine), sulfhydryl compounds (e.g., glutathione), lycine pidolate, arginine pilolate, nordihydroguaiaretic acid, bioflavonoids, curcumin, lysine, methionine, proline, superoxide dismutase, silymarin, tea extracts, grape skin/seed extracts, melanin, and rosemary extracts may be used. Preferred anti-oxidants/radical scavengers are selected from tocopherol sorbate and other esters of tocopherol, more preferably tocopherol sorbate. For example, the use of tocopherol sorbate in topical compositions and applicable to the present invention is described in U.S. Patent No. 4,847,071, issued on July 11, 1989 to Donald L. Bissett, Rodney D. Bush and Ranjit Chatterjee.

Flavonoids

The compositions of the present invention may optionally contain a flavonoid compound. Flavonoids are broadly disclosed in U.S. Patents 5,686,082 and 5,686,367, both of which are herein incorporated by reference. Flavonoids suitable for use in the present invention are flavanones selected from unsubstituted flavanones, mono-substituted flavanones, and mixtures thereof; chalcones selected from unsubstituted chalcones, mono-substituted chalcones, di- substituted chalcones, tri-substituted chalcones, and mixtures thereof; flavones selected from unsubstituted flavones, mono-substituted flavones, di-substituted flavones, and mixtures thereof; one or more isoflavones; coumarins selected from unsubstituted coumarins, mono-substituted coumarins, di-substituted coumarins, and mixtures thereof; chromones selected from unsubstituted chromones, mono-substituted chromones, di-substituted chromones, and mixtures thereof; one or more dicoumarols; one or more chromanones; one or more chromanols; isomers (e.g., cis/trans isomers) thereof; and mixtures thereof. By the term "substituted" as used herein means flavonoids wherein one or more hydrogen atom of the flavonoid has been independently replaced with hydroxyl, C1-C8 alkyl, C1-C4 alkoxyl, O-glycoside, and the like or a mixture of these substituents.

Examples of suitable flavonoids include, but are not limited to, unsubstituted flavanone, mono-hydroxy flavanones (e.g., 2'-hydroxy flavanone, 6-hydroxy flavanone, 7-hydroxy flavanone, etc.), mono-alkoxy flavanones (e.g., 5-methoxy flavanone, 6-methoxy flavanone, 7- methoxy flavanone, 4'-methoxy flavanone, etc.), unsubstituted chalcone (especially unsubstituted trans-chalcone), mono-hydroxy chalcones (e.g., 2'-hydroxy chalcone, 4'-hydroxy chalcone, etc.), di-hydroxy chalcones (e.g., 2',4-dihydroxy chalcone, 2',4'-dihydroxy chalcone, 2,2'-dihydroxy chalcone, 2',3-dihydroxy chalcone, 2',5'-dihydroxy chalcone, etc.), and tri-hydroxy chalcones (e.g., 2',3',4'-trihydroxy chalcone, 4,2',4'-trihydroxy chalcone, 2,2',4'-trihydroxy chalcone, etc.), unsubstituted flavone, 7,2'-dihydroxy flavone, 3',4'-dihydroxy naphthoflavone, 4'-hydroxy flavone, 5,6-benzoflavone, and 7,8-benzoflavone, unsubstituted isoflavone, daidzein (7,4'- dihydroxy isoflavone), 5,7-dihydroxy-4'-methoxy isoflavone, soy isoflavones (a mixture extracted from soy), unsubstituted coumarin, 4-hydroxy coumarin, 7-hydroxy coumarin, 6-hydroxy-4- methyl coumarin, unsubstituted chromone, 3-formyl chromone, 3-formyl-6-isopropyl chromone, unsubstituted dicoumarol, unsubstituted chromanone, unsubstituted chromanol, and mixtures thereof..

They can be synthetic materials or obtained as extracts from natural sources (e.g., plants). The naturally sourced material can also further be derivatized (e.g., an ester or ether derivative prepared following extraction from a natural source). Flavonoid compounds useful herein are commercially available from a number of sources, e.g., Indofine Chemical Company, Inc. (Somerville, New Jersey), Steraloids, Inc. (Wilton, New Hampshire), and Aldrich Chemical Company, Inc. (Milwaukee, Wisconsin).

Mixtures of the above flavonoid compounds may also be used.

The herein described flavonoid compounds are preferably present in the instant invention at concentrations of from about 0.01% to about 20%, more preferably from about 0.1% to about 10% , and still more preferably from about 0.5% to about 5%.

Anti-Inflammatory Agents

A safe and effective amount of an anti-inflammatory agent may be added to the compositions of the present invention, preferably from about 0.1% to about 10%, more preferably from about 0.5% to about 5%, of the composition. The anti-inflammatory agent enhances the skin appearance benefits of the present invention, e.g., such agents contribute to a more uniform and acceptable skin tone or color. The exact amount of anti-inflammatory agent to be used in the compositions will depend on the particular anti-inflammatory agent utilized since such agents vary widely in potency.

Steroidal anti-inflammatory agents, including but not limited to, corticosteroids such as hydrocortisone, hydroxyltriamcinolone, alpha-methyl dexamethasone, dexamethasone-phosphate, beclomethasone dipropionates, clobetasol valerate, desonide, desoxymethasone, desoxycorticosterone acetate, dexamethasone, dichlorisone, diflorasone diacetate, diflucortolone valerate, fluadrenolone, fluclorolone ^■ acetonide, fludrocortisone, flumethasone pivalate, fluosinolone acetonide, fluocinonide, flucortine butylesters, fluocortolone, fluprednidene (fluprednylidene) acetate, flurandrenolone, halcinonide, hydrocortisone acetate, hydrocortisone butyrate, methylprednisolone, triamcinolone acetonide, cortisone, cortodoxone, flucetonide, fludrocortisone, difluorosone diacetate, fluradrenolone, fludrocortisone, diflurosone diacetate, fluradrenolone acetonide, medrysone, amcinafel, amcinafide, betamethasone and the balance of its esters, chloroprednisone, chlorprednisone acetate, clocortelone, clescinolone, dichlorisone, diflurprednate, flucloronide, flunisolide, fluoromethalone, fluperolone, fluprednisolone, hydrocortisone valerate, hydrocortisone cyclopentylpropionate, hydrocortamate, meprednisone, paramethasone, prednisolone, prednisone, beclomethasone dipropionate, triamcinolone, and mixtures thereof may be used. The preferred steroidal anti-inflammatory for use is hydrocortisone.

A second class of anti-inflammatory agents which is useful in the compositions includes the nonsteroidal anti-inflammatory agents. The variety of compounds encompassed by this group are well-known to those skilled in the art. For detailed disclosure of the chemical structure, synthesis, side effects, etc. of non-steroidal anti-inflammatory agents, one may refer to standard texts, including Anti-inflammatory and Anti-Rheumatic Drugs. K. D. Rainsford, Vol. I-III, CRC Press, Boca Raton, (1985), and Anti-inflammatory Agents. Chemistry and Pharmacology. 1, R. A. Scherrer, et al., Academic Press, New York (1974).

Specific non-steroidal anti-inflammatory agents useful in the composition invention include, but are not limited to:

1) the oxicams, such as piroxicam, isoxicam, tenoxicam, sudoxicam, and CP-14,304;

2) the salicylates, such as aspirin, disalcid, benorylate, trilisate, safapryn, solprin, diflunisal, and fendosal;

3) the acetic acid derivatives, such as diclofenac, fenclofenac, indomethacin, sulindac, tolmetin, isoxepac, fiirofenac, tiopinac, zidometacin, acematacin, fentiazac, zomepirac, clindanac, oxepinac, felbinac, and ketorolac;

4) the fenamates, such as mefenamic, meclofenamic, flufenamic, niflumic, and tolfenamic acids;

5) the propionic acid derivatives, such as ibuprofen, naproxen, benoxaprofen, flurbiprofen, ketoprofen, fenoprofen, fenbufen, indopropfen, pirprofen, carprofen, oxaprozin, pranoprofen, miroprofen, tioxaprofen, suprofen, alminoprofen, and tiaprofenic; and

6) the pyrazoles, such as phenylbutazone, oxyphenbutazone, feprazone, azapropazone, and trimethazone.

Mixtures of these non-steroidal anti-inflammatory agents may also be employed, as well as the dermatologically acceptable esters of these agents. For example, etofenamate, a flufenamic acid derivative, is particularly useful for topical application. Of the nonsteroidal anti- inflammatory agents, ibuprofen, naproxen, flufenamic acid, etofenamate, aspirin, mefenamic acid, meclofenamic acid, piroxicam and felbinac are preferred; ibuprofen, naproxen, ketoprofen, etofenamate, aspirin and flufenamic acid are more preferred.

Finally, so-called "natural" anti-inflammatory agents are useful in methods of the present invention. Such agents may suitably be obtained as an extract by suitable physical and/or chemical isolation from natural sources (e.g., plants, fungi, by-products of microorganisms) or can be synthetically prepared. For example, candelilla wax, bisabolol (e.g., alpha bisabolol), aloe vera, plant sterols (e.g., phytosterol), Manjistha (extracted from plants in the genus Rubia, particularly Rubia Cordifolia). and Guggal (extracted from plants in the genus Commiphora. particularly Commiphora Mukul). kola extract, chamomile, red clover extract, and sea whip extract, may be used.

Additional anti-inflammatory agents useful herein include compounds of the Licorice (the plant genus/species Glycyrrhiza glabra) family, including glycyrrhetic acid, glycyrrhizic acid, and derivatives thereof (e.g. esters). Suitable esters include C2 - C24 saturated or unsaturated esters of the acids, preferably Ci ø - C24, more preferably Cjg - C24. Specific examples of the foregoing include oil soluble licorice extract, the glycyrrhizic and glycyrrhetic acids themselves.

Anti-Cellulite Agents

The compositions of the present invention may also contain a safe and effective amount of an anti-cellulite agent. Suitable agents may include, but are not limited to, xanthine compounds (e.g., caffeine, theophylline, theobromine, and aminophylline).

Topical Anesthetics

The compositions of the present invention may also contain a safe and effective amount of a topical anesthetic. Examples of topical anesthetic drugs include benzocaine, lidocaine, bupivacaine, chlorprocaine, dibucaine, etidocaine, mepivacaine, tetracaine, dyclonine, hexylcaine, procaine, cocaine, ketamine, pramoxine, phenol, and pharmaceutically acceptable salts thereof.

Skin Soothing and Skin Healing Actives

The compositions of the present invention may comprise a skin soothing or skin healing active. Skin soothing or skin healing actives suitable for use herein include panthenoic acid derivatives (including panthenol, dexpanthenol, ethyl panthenol), aloe vera, allantoin, bisabolol, and dipotassium glycyrrhizinate. A safe and effective amount of a skin soothing or skin healing active may be added to the present composition, preferably, from about 0.1% to about 30%, more preferably from about 0.5% to about 20%, still more preferably from about 0.5% to about 10 %, by weight of the composition formed. a) bisabolol

The topical compositions of the present invention may also contain a safe and effective amount of bisabolol. Bisabolol is a naturally occurring unsaturated monocyclic terpene alcohol having the following structure

It is the primary active component of chamomile extract/oil. Bisabolol can be synthetic (d,l - alpha-isomer or (+/-)-alpha-isomer) or natural ((-)-alpha-isomer) in origin and can be used as essentially pure compounds or mixtures of compounds (e.g., extracts from natural sources such as chamomile). The alpha form of bisabolol (a-bisabolol) is used in a variety of cosmetic products as a skin conditioning or soothing agent. As used herein, "bisabolol" includes chamomile extract or oil and any isomers and tautomers of such. Suitable bisabolol compounds are commercially available as a natural material from Dragoco (Totowa, New Jersey) under the product name alpha- bisabolol natural and as a synthetic material from Fluka (Milwaukee, Wisconsin) under the product name alpha-bisabolol.

In the compositions of the present invention, the composition preferably contains from about 0.001% to about 50%, by weight of the composition, more preferably from about 0.01% to about 20%, even more preferably from about 0.01% to about 15%, and still more preferably from about 0.1% to about 10%, of bisabolol, even more preferably from about 0.1% to about 5%.

Antimicrobial and Antifungal Actives

The compositions of the present invention may contain an antimicrobial or antifungal active. Such actives are capable of destroying microbes, preventing the development of microbes or preventing the pathogenic action of microbes. A safe and effective amount of an antimicrobial or antifungal active may be added to the present compositions, preferably, from about 0.001% to about 10%, more preferably from about 0.01% to about 5%, and still more preferably from about 0.05% to about 2%.

Preferred examples of actives useful herein include those selected from salicylic acid, benzoyl peroxide, 3-hydroxy benzoic acid, glycolic acid, lactic acid, 4-hydroxy benzoic acid, acetyl salicylic acid, 2-hydroxybutanoic acid, 2-hydroxypentanoic acid, 2-hydroxyhexanoic acid, cis-retinoic acid, trans-retinoic acid, retinol, phytic acid, N-acetyl-L-cysteine, lipoic acid, azelaic acid, arachidonic acid, benzoylperoxide, tetracycline, ibuprofen, naproxen, hydrocortisone, acetominophen, resorcinol, phenoxyethanol, phenoxypropanol, phenoxyisopropanol, 2,4,4'- trichloro-2'-hydroxy diphenyl ether, 3,4,4'-trichlorocarbanilide, octopirox, lidocaine hydrochloride, clotrimazole, miconazole, ketoconazole, neocycin sulfate, and mixtures thereof.

Sunscreen Actives Exposure to ultraviolet light can result in excessive scaling and texture changes of the stratum comeum. Therefore, the compositions of the subject invention may optionally contain a sunscreen active. As used herein, "sunscreen active" includes both sunscreen agents and physical sunblocks. Suitable sunscreen actives may be organic or inorganic.

Inorganic sunscreens useful herein include the following metallic oxides; titanium dioxide having an average primary particle size of from about 15 nm to about 100 nm, zinc oxide having an average primary particle size of from about 15 nm to about 150 nm, zirconium oxide having an average primary particle size of from about 15 nm to about 150 nm, iron oxide having an average primary particle size of from about 15 nm to about 500nm, and mixtures thereof. When used herein, the inorganic sunscreens are present in the amount of from about 0.1% to about 20%, preferably from about 0.5% to about 10%, more preferably from about 1% to about 5%, by weight of the composition.

A wide variety of conventional organic sunscreen actives are suitable for use herein. Sagarin, et al., at Chapter VIII, pages 189 et seq., of Cosmetics Science and Technology (1972), discloses numerous suitable actives. Specific suitable sunscreen actives include, for example: p- aminobenzoic acid, its salts and its derivatives (ethyl, isobutyl, glyceryl esters; p- dimethylaminobenzoic acid); anthranilates (i.e., o-amino-benzoates; methyl, menthyl, phenyl, benzyl, phenylethyl, linalyl, terpinyl, and cyclohexenyl esters); salicylates (amyl, phenyl, octyl, benzyl, menthyl, glyceryl, and di-pro-pyleneglycol esters); cinnamic acid derivatives (menthyl and benzyl esters, a-phenyl cinnamonitrile; butyl cinnamoyl pyruvate); dihydroxycinnamic acid derivatives (umbelliferone, methylumbelliferone, methylaceto-umbelliferone); trihydroxy- cinnamic acid derivatives (esculetin, methylesculetin, daphnetin, and the glucosides, esculin and daphnin); hydrocarbons (diphenylbutadiene, stilbene); dibenzalacetone and benzalacetophenone; naphtholsulfonates (sodium salts of 2-naphthol-3,6-disulfonic and of 2-naphthol-6,8-disulfonic acids); di-hydroxynaphthoic acid and its salts; o- and p-hydroxybiphenyldisulfonates; coumarin derivatives (7-hydroxy, 7-methyl, 3-phenyl); diazoles (2-acetyl-3-bromoindazole, phenyl benzoxazole, methyl naphthoxazole, various aryl benzothiazoles); quinine salts (bisulfate, sulfate, chloride, oleate, and tannate); quinoline derivatives (8-hydroxyquinoline salts, 2- phenylquinoline); hydroxy- or methoxy-substituted benzophenones; uric and violuric acids; tannic acid and its derivatives (e.g., hexaethylether); utyl carbotol) (6-propyl piperonyl) ether; hydroquinone; benzophenones (oxybenzene, sulisobenzone, dioxybenzone, benzoresorcinol, 2,2',4,4'-tetrahydroxybenzophenone, 2,2'-dihydroxy-4,4'-dimethoxybenzophenone, octabenzone; 4-isopropyldibenzoylmethane; butylmethoxydibenzoylmethane; etocrylene; octocrylene; [3-(4'- methylbenzylidene bornan-2-one), terephthalylidene dicamphor sulfonic acid and 4-isopropyl-di- benzoylmethane. Of these, 2-ethylhexyl-p-methoxycinnamate (commercially available as PARSOL MCX), 4,4'-t-butyl methoxydibenzoyl-methane (commercially available as PARSOL 1789), 2-hydroxy-4- methoxybenzophenone, octyldimethyl-p-aminobenzoic acid, digalloyltrioleate, 2,2-dihydroxy-4- methoxybenzophenone, ethyl-4-(bis(hydroxy-propyl))aminobenzoate, 2-ethylhexyl-2-cyano-3 ,3 - diphenylacrylate, 2-ethylhexyI-salicyIate, glyceryl-p-aminobenzoate, 3,3,5-tri- methylcyclohexylsalicylate, methylanthranilate, p-dimethyl-aminobenzoic acid or aminobenzoate, 2-ethylhexyl-p-dimethyl-amino-benzoate, 2-phenylbenzimidazole-5-sulfonic acid, 2-(p- dimethylaminophenyl)-5-sulfonicbenzoxazoic acid, octocrylene and mixtures of these compounds, are preferred.

More preferred organic sunscreen actives useful in the compositions useful in the subject invention are 2-ethylhexyl-p-methoxycinnamate, butylmethoxydibenzoyl-methane, 2-hydroxy-4- methoxybenzo-phenone, 2-phenylbenzimidazole-5-sulfonic acid, octyldimethyl-p-aminobenzoic acid, octocrylene and mixtures thereof.

Also particularly useful in the compositions are sunscreen actives such as those disclosed in U.S. Patent No. 4,937,370 issued to Sabatelli on June 26, 1990, and U.S. Patent No. 4,999,186 issued to Sabatelli & Spirnak on March 12, 1991. The sunscreening agents disclosed therein have, in a single molecule, two distinct chromophore moieties which exhibit different ultra-violet radiation absorption spectra. One of the chromophore moieties absorbs predominantly in the UVB radiation range and the other absorbs strongly in the UVA radiation range.

Preferred members of this class of sunscreening agents are 4-N,N-(2-ethylhexyl)methyl- aminobenzoic acid ester of 2,4-dihydroxybenzophenone; N,N-di-(2-ethylhexyl)-4-aminobenzoic acid ester with 4-hydroxydibenzoylmethane; 4-N,N-(2-ethylhexyl)methyl-aminobenzoic acid ester with 4-hydroxydibenzoylmethane; 4-N,N-(2-ethylhexyl)methyl-aminobenzoic acid ester of 2-hydroxy-4-(2-hydroxyethoxy)benzophenone; 4-N,N-(2-ethylhexyl)-methylaminobenzoic acid ester of 4-(2-hydroxyethoxy)dibenzoylmethane; N,N-di-(2-ethylhexyl)-4-aminobenzoic acid ester of 2-hydroxy-4-(2-hydroxyethoxy)benzophenone; and N,N-di-(2-ethylhexyl)-4-aminobenzoic acid ester of 4-(2-hydroxyethoxy)dibenzoylmethane and mixtures thereof.

Especially preferred sunscreen actives include 4,4'-t-butylmethoxydibenzoylmethane, 2- ethylhexyl-p-methoxycinnamate, phenyl benzimidazole sulfonic acid, and octocrylene.

A safe and effective amount of the organic sunscreen active is used, typically from about 1% to about 20%, more typically from about 2% to about 10% by weight of the composition. Exact amounts will vary depending upon the sunscreen or sunscreens chosen and the desired Sun Protection Factor (SPF).

Hardeners/Softeners The personal care compositions herein, in some embodiments, may include a safe and effective amount of a hardener or softener element. Examples of such hardener/softener materials include poly(t-butyl styrene), poly(t-butyl styrene co-styrene), and mixtures thereof.

Particulate Material

The compositions of the present invention may, in some embodiments, contain a particulate material, preferably a metallic oxide. These particulates can be coated or uncoated, charged or uncharged. Charged particulate materials are disclosed in U.S. Patent No. 5,997,887, to Ha, et al., incorporated herein by reference. Particulate materials useful herein include; bismuth oxychloride, iron oxide, mica, mica treated with barium sulfate and Ti02, silica, nylon, polyethylene, talc, styrene, polypropylene, ethylene/acrylic acid copolymer, sericite, aluminum oxide, silicone resin, barium sulfate, calcium carbonate, cellulose acetate, polymethyl methacrylate, and mixtures thereof.

Conditioning Agents

The compositions of the present invention may contain a conditioning agent selected from humectants, moisturizers, or skin conditioners. A variety of these materials can be employed and each can be present at a level of from about 0.01% to about 20%, more preferably from about 0.1% to about 10. These materials include, but are not limited to, guanidine; urea; glycolic acid; salicylic acid; lactic acid (e.g., ammonium and quaternary alkyl ammonium); aloe vera in any of its variety of forms (e.g., aloe vera gel); polyhydroxy alcohols such as sorbitol, mannitol, xylitol, erythritol, glycerol, hexanetriol, butanetriol, propylene glycol, butylene glycol, hexylene glycol and the like; polyethylene glycols; sugars (e.g., melibiose) and starches; sugar and starch derivatives (e.g., alkoxylated glucose, fructose, glucosamine); hyaluronic acid; lactamide monoethanolamine; acetamide monoethanolamine; panthenol; allantoin; and mixtures thereof. Also useful herein are the propoxylated glycerols described in U. S. Patent No. 4,976,953, to Orr et al, issued December 11, 1990.

Also useful are various C₁-C₃₀ monoesters and polyesters of sugars and related materials. These esters are derived from a sugar or polyol moiety and one or more carboxylic acid moieties. Such ester materials are further described in, U. S. Patent No. 2,831,854, U. S. Patent No. 4,005,196, to Jandacek, issued January 25, 1977; U. S. Patent No. 4,005,195, to Jandacek, issued January 25, 1977, U. S. Patent No. 5,306,516, to Letton et al, issued April 26, 1994; U. S. Patent No. 5,306,515, to Letton et al, issued April 26, 1994; U. S. Patent No. 5,305,514, to Letton et al, issued April 26, 1994; U. S. Patent No. 4,797,300, to Jandacek et al, issued January 10, 1989; U. S. Patent No. 3,963,699, to Rizzi et al, issued June 15, 1976; U. S. Patent No. 4,518,772, to Volpenhein, issued May 21, 1985; and U. S. Patent No. 4,517,360, to Volpenhein, issued May 21, 1985. Preferably, the conditioning agent is selected from urea, guanidine, sucrose polyester, panthenol, dexpanthenol, allantoin, and combinations thereof.

Thickening Agent

The compositions of the present invention can contain one or more thickening agents, for example clays, gums, polymeric thickeners. When present, the compositions preferably provide from about 0.1% to about 5%, more preferably from about 0.1% to about 4%, and still more preferably from about 0.25% to about 3%, by weight of the composition of the thickening agent.

Composition Preparation

The compositions useful for the methods of the present invention are generally prepared by conventional methods such as are known in the art of making topical compositions. Such methods typically involve mixing of the ingredients in one or more steps to a relatively uniform state, with or without heating, cooling, application of vacuum, and the like.

The topical compositions of the present invention may be formulated as a facial skin cosmetic, eye cosmetic, lip cosmetic, scalp hair styling aid, facial hair styling aid, moisturizer, wrinkle soothing serum, lotion, mascara, spa product, body firming cream, cellulite reducing cream, skin facial mask, skin lotion, skin cream, skin gel, eye gel, eye cream, lip gel, lip cream, cosmetic, foundation, or any other commonly known skin product or treatment.

A multiple-step regimen may also be employed. For example, an adhesive elastomeric polymer basecoat may be applied and then the inorganic colloid in solution be applied either in combination with the basecoat application or after a brief drying period. Additionally, a dual- barrel or dual-pipette system may be implemented in which the inorganic colloid is applied from one barrel and the adhesive elastomeric polymer is applied from another barrel.

Methods of Use

The compositions of the present invention are useful for modifying the appearance of skin and hair. Modifying the appearance of hair includes styling scalp hair, eyelashes, eyebrows, beard and/or mustache. A preferred use of the compositions of the present invention is the curling of eyelashes by application of the compositions herein with a suitable implement e.g., a eyelash wand, or with the fingers.

Modifying the appearance of skin includes reducing the appearance of fine lines and/or wrinkles on the skin, reducing the appearance of eye bags and dark circles under the eyes, sagging skin, scars/marks, dimples, pores, stretch marks, roughness, skin surface blemishes, frown lines, expression lines, rhytides, blemishes, photodamage, crevices, and/or unevenness. Furthermore, modifying the appearance of skin includes reducing the appearance of cellulite.

In some embodiments of the present invention, the modification of the appearance of skin and/or hair may be enhanced by the addition of a skin or hair active. Examples of skin care actives that may be added to compositions of the present invention include vitamin B₃ compounds (e.g. niacinamide), panthenol and panthenoic acid, vitamin E compounds (e.g. tocopherol acetate), and retinoids (e.g. retinyl propionate). Regulation of the keratinous tissue conditions of the skin with such actives in combination with the film-forming inorganic colloid and adhesive elastomeric polymer can include prophylactic and therapeutic regulation. For example, such regulating methods are directed to thickening keratinous tissue (i.e., building the epidermis and/or dermis layers of the skin and where applicable the keratinous layers of the nail and hair shaft) and preventing and/or retarding atrophy of mammalian skin, preventing and/or retarding the appearance of spider vessels and/or red blotchiness on mammalian skin, preventing and/or retarding the appearance of dark circles under the eye of a mammal, preventing and/or retarding sallowness of mammalian skin, preventing and/or retarding sagging of mammalian skin, softening and/or smoothing lips, hair and nails of a mammal, preventing and/or relieving itch of mammalian skin, regulating skin texture (e.g. wrinkles and fine lines), and improving skin color (e.g. redness, freckles).

In a preferred embodiment, the composition further includes a chronic active, such as niacinamide, and the composition is chronically applied to the skin. By "chronic topical application" is meant continued topical application of the composition over an extended period during the subject's lifetime, preferably for a period of at least about one week, more preferably for a period of at least about one month, even more preferably for at least about three months, even more preferably for at least about six months, and more preferably still for at least about one year. While benefits are obtainable after various maximum periods of use (e.g., five, ten or twenty years), it is preferred that chronic application continue throughout the subject's lifetime. Typically applications would be on the order of about once per day over such extended periods, however application rates can vary from about once per week up to about three times per day or more.

A wide range of quantities of the compositions of the present invention can be employed to provide a skin appearance and/or feel benefit. Quantities of the present compositions which are typically applied per application are, in mg composition/cm^ skin, from about 0.1 mg/cm^ to about 100 mg/cn_A A particularly useful application amount is about 1 mg/cm^ to about 10 mg/cm^. Modifying and/or regulating skin appearance, feel, and/or condition is preferably practiced by applying a composition in the form of a skin lotion, cream, gel, foam, ointment, paste, emulsion, spray, conditioner, tonic, cosmetic, lipstick, foundation, nail polish, after-shave, or the like which is preferably intended to be left on the skin or other keratin structure for some esthetic, prophylactic, therapeutic or other benefit (i.e., a "leave-on" composition). After applying the composition to the skin, it is preferably left on the skin for a period of at least about 15 minutes, more preferably at least about 30 minutes, even more preferably at least about 1 hour, still more preferably for at least several hours, e.g., 12 hours. Any part of the external portion of the face, body, hair, and/or nails can be treated, e.g., face, lips, under-eye area, eyelids, scalp, neck, torso, amis, hands, legs, feet, fingernails, toenails, scalp hair, eyelashes, eyebrows, etc. The composition can be applied with the fingers or with an implement or device (e.g., pad, cotton ball, applicator pen, spray applicator, and the like). The compositions, after drying on the skin or hair, may be "refreshed" or "touched up" by directly applying additional amounts of the composition to the area in need of treatment.

Another approach to ensure a continuous exposure of the skin to at least a minimum level of the composition is to apply the compound by use of a patch applied, e.g., to the face. Such an approach is particularly useful for problem skin areas needing more intensive treatment (e.g., facial crows feet area, frown lines, under eye area, and the like). The patch can be occlusive, semi-occlusive or non-occlusive and can be adhesive or non-adhesive. The composition can be contained within the patch or be applied to the skin prior to application of the patch. The patch can also include additional actives such as chemical initiators for exothermic reactions such as those described in U.S. Patents numbered 5,821,250, 5,981,547, and 5,972,957 to Wu, et al. The patch is preferably left on the skin for a period of at least about 5 minutes, more preferably at least about 15 minutes, more preferably still at least about 30 minutes, even more preferably at least about 1 hour, still more preferably at night as a form of night therapy.

The composition according to the invention can be packaged in its own bottle. It can also be packaged in two separate receptacles, each receptacle containing either the inorganic colloid or the elastomeric polymer. The separate receptacles may provide ease in application or product formulation. The separate receptacles may also allow the consumer to control the level of physical stress on the skin (and resulting wrinkle-reduction benefit) achieved by a particular application.

Examples

The following examples further describe and demonstrate embodiments within the scope of the present invention. The examples are given solely for the purpose of illustration and are not to be construed as limitations of the present invention, as many variations thereof are possible without departing from the spirit and scope of the invention.

Examples 1-4 Skin Serum

¹ Available from Nalco Chemical as Nalco 1115 Colloidal silica.

² Available from B.F. Goodrich as Hystretch 43, a 50wt% aqueous latex.

³ Available from National Starch as Flexanl30, a 28wt% aqueous solution or Versaflex 5000 powder.

⁴Available from Collaborative Labs as SanSurf Petrolatum, a 50wt% aqueous microemulsion. ⁵ Available from Roche as Niacinamide No. 69905 ⁶Available from Kobo as EA209 pigment powder beads.

Making instructions:

1. All water soluble ingredients (e.g. sodium polystyrene sulfonate, niacinamide) are combined at < 100 rpm low shear mixing to create a water phase.

2. Then the inorganic colloid is added to the water phase with mixing.

3. Then the water-dispersed polymers (i.e. elastomer latex) are added with mixing.

4. Then any of the other particle materials (such as pigments) are added with mixing.

After application of the composition to the skin, an excellent, aesthetically-pleasing wrinkle-reducing effect was obtained. Examples 5-7

Skin Cream

¹ Available from Nalco Chemical as Nalco 1115 Colloidal silica.

² Available from B.F. Goodrich as Hystretch 43, a 50wt% aqueous latex.

³ Available from Shell Oil Company as Kraton LVSI, neat. ⁴Available from Presperse Corporation as Permethyl 99A. ⁵Available from Kobo as Tospearl 145 pigment powder beads, available from Dow Coming as DC5225C.

⁷Available from Dow Coming as DC200 fluid. ⁸ Available from Roche as Vitamin A Alcohol. ⁹Available from BASF as Vitamin E Acetate.

¹⁰ Available from Roche as Niacinamide No. 69905

¹¹ Available from Roche as DL-Panthenol No. 63915.

¹²Available from Southern Clay Company and Waverly as Laponite XLS, Laponite XLG

Making instructions:

1. All the water soluble ingredients (e.g. niacinamide) are combined in water at <100 rpm low shear mixing to form a water phase.

2. Then the inorganic colloid is added to the water phase. 3. Then the water dispersed polymers (i.e. elastomer latex) are added.

4. Then the thickener(s) (e.g. hectorite) are added and the mixing speed is increased to 500 rpm for 30-60 minutes.

5. Then the oil dissolved ingredients (e.g. Kraton in Permethyl) and emulsifiers (if present) are added into the water phase.

6. Then the oil dissolved ingredients are dispersed thoroughly at 1000 rpm with a low shear mixing blade.

7. Then the particle materials (such as pigments) are added and homogenized at <1000 rpm.

After application of the composition to the skin, an excellent, aesthetically-pleasing wrinkle-reducing effect was obtained.

Examples 8-10 Wrinkle Reducing Foundation

Available from B.F. Goodrich as Goodrite, a 50wt% aqueous latex.

² Available from Nalco Chemical as Nalco 1115 Colloidal silica. ³Available from Dow Coming as DC5225C.

⁴Available from Dow Coming as DC200 fluid. ⁵Available from Presperse Corporation as Permethyl 99A. ⁶ Available from Shell Oil Company as Kraton LVSI, neat. ⁷ Available from BASF as Vitamin E Acetate.

⁸ Available from General Electric as SRI 000 Resin. ¹⁰ Available from Roche as Niacinamide No. 69905

Making instructions:

1. All the water soluble ingredients (e.g. niacinamide) are added in water with <100 rpm low shear mixing to form a water phase.

2. Then the inorganic colloid is added to the water phase.

3. Then the water dispersed polymers (i.e. elastomer latex) are added.

4. Then the oil dissolved ingredients (e.g. Kraton into Permethyl) and emulsifiers (if present) are added into the water phase.

5. Then the oil dissolved ingredients are dispersed thoroughly at 1000 rpm with low shear mixing blade.

6. Then the particle materials (such as pigment) are added and the mixture is homogenized at <1000 rpm or by sonication.

After application of the composition to the skin, an excellent, aesthetically pleasing wrinkle-reducing and aesthetically-pleasing even skin tone were obtained.

Examples 11-12 Exfoliating Peel-off Mask

Available from Nalco Chemical as Nalco 1115 Colloidal silica.

² Available from B.F. Goodrich as Hystretch 43, a 50wt% aqueous latex.

³ Available from Roche as Niacinamide No. 69905 Available from Southern Clay Company and Waverly as Laponite XLS, Laponite XLG

Making instructions: 1. All the water soluble ingredients (e.g. niacinamide) are combined in water with <100 rpm low shear mixing to form a water phase.

2. Then the inorganic colloid is added to the water phase.

3. Then the water dispersed polymers (i.e. elastomer latex) are added.

4. Then the thickeners (e.g. hectorite) are added with increased mixing speed to 500 rpm for 30- 60 minutes.

5. Then the composition is mixed at 1000 rpm with a low shear mixing blade until thoroughly dispersed.

After application of the composition to the skin, an excellent, aesthetically-pleasing wrinkle-reducing and aesthetically-pleasing skin smoothing effect was obtained.

Examples 13-14 Skin Anti-wrinkling Foam

Available from Nalco Chemical as Nalco 1115 Colloidal silica.

² Available from Dow Chemical as Propellant A-46.

³ Available from B.F. Goodrich as Hystretch 43, a 50wt% aqueous latex.

⁴ Available from Roche as Niacinamide No. 69905 ⁵Available from Roche as DL-Panthenol No. 63915.

⁶ Available from Lipo as Orgasol pigment powder beads.

Making instructions:

1. All water soluble ingredients and water dispersed ingredients (such as aqueous latex, colloidal silica) are combined with <100 rpm low shear mixing to form a water phase. 2. Then the particles (such as pigment powder beads) and oil additives are dispersed in the water phase under moderate shear 100-500 rpm,

3. Then the composition is pressurized by adding the propellant and capping the packaging to create a self-foaming mousse.

After application of the product to the skin, an excellent, aesthetically-pleasing wrinkle reducing effect was obtained.

Claims

What is claimed is:

1. A topical personal care composition safe and effective for modifying the appearance of skin or hair, comprising: a) from about 0.1% to about 60%, by weight of the composition, of an inorganic film-forming colloid having a Tg of greater than 25°C; b) from about 0.1% to about 70%, by weight of the composition, of an adhesive elastomeric polymer having a Tg of less than 40°C; and c) from about 10% to about 99.8%, by weight of the composition, of a dermatologically acceptable carrier for the inorganic film-forming colloid and the elastomeric polymer.

3. A composition according to claim 1 wherein the inorganic colloid is in the form of a sol, wherein said sol comprises a dispersion of the inorganic colloid in a polar solvent.

4. A composition according to claim 1 wherein the inorganic colloid is selected from the group consisting of silica, boehmite alumina, zirconium dioxide, zirconium polyanions, boron nitride, nickel hydroxide, nickel acetate, zinc hydroxide, titanium dioxide and mixtures thereof.

5. A composition according to claim 4 wherein the inorganic colloid is silica.

6. A composition according to claim 5 wherein the silica is negatively charged, has an average primary particle size of less than about 50 nm, and a surface area of greater than about 100 meter ² /gram.

7. A composition according to claim 3 wherein the inorganic colloid is selected from the group consisting of titanium dioxide, zinc oxide, zinc hydroxide, silica, boehmite alumina, zirconium oxide, zirconium polyanions, boron nitride, nickel hydroxide, nickel acetate, and mixtures thereof.

8. A composition according to claim 7 wherein the inorganic colloid is silica.

9. A composition according to claim 1 wherein the elastomeric polymer is selected from the group consisting of oil soluble elastomers, latexes, polar solvent-soluble elastomers, and mixtures thereof.

10. A composition according to claim 9 wherein the elastomeric polymer is an oil soluble elastomer.

11. A composition according to claim 9 wherein the elastomeric polymer is a latex.

12. A composition according to claim 1 wherein the elastomeric polymer is selected from the group consisting of styrene-isoprene elastomers, styrene-butadiene elastomers, styrene- ethylene/propylene-styrene elastomers, styrene-ethylene/butylene-styrene elastomers, terminal hydroxylated polyethylene/butylene elastomers, ethylene-propylene elastomers, random thermoplastic elastomers, polystyrene-co-polyethylenepropylene elastomers, styrene-acrylate elastomer latex, silicone elastomer latex, acrylic acid ester elastomer latex, styrene-butadiene elastomer latex, crosslinked polyvinyl alcohol, polyoxyethylene-co-vinyl alcohol, and mixtures thereof.

13. The composition of claim 12 wherein the elastomeric polymer is a linear copolymer, branched copolymer, random copolymer, branched copolymer, block copolymer, di-block copolymer, tri-block copolymer, multi-block copolymer, grafted copolymer, or star-shaped copolymer.

14. A composition according to claim 12 wherein the elastomeric polymer is selected from the group consisting of silicone elastomer latexes, styrene-acrylate elastomer latexes and mixtures thereof.

15. A composition according to claim 1 wherein the carrier comprises a diluent selected from the group consisting of water, aliphatic hydrocarbons, aliphatic alcohols, silicones, ketones, esters, alcohols, glycols, glycol ethers, aromatic hydrocarbons, and mixtures thereof.

16. A composition according to claim 15 wherein the carrier comprises water.

17. A composition according to claim 1 wherein the composition further comprises an oil- soluble polymer.

18. A composition according to claim 1 wherein the composition further comprises an ionic polymer.

19. A composition according to claim 1 wherein the carrier is an emulsion.

20. A composition according to claim 1 wherein the composition is in a form selected from the group consisting of facial skin cosmetics, eye cosmetics, lip cosmetics, scalp hair styling aids, facial hair styling aids, moisturizers, wrinkle soothing serums, lotions, mascaras, skin facial masks, eye gels, eye creams, lip gels, lip creams, cosmetics, and foundations.

21. A composition according to claim 1 wherein the composition further comprises a skin care active selected from the group consisting of retinoids, vitamin B₃ compounds, vitamin E compounds, panthenol, titanium dioxide, salicylic acid, and mixtures thereof.

22. A method of improving the appearance of skin texture, color and/or firmness, comprising topically applying to skin in need of such treatment an effective amount of the composition of claim 1.

23. A method of styling hair, comprising topically applying to the hair an effective amount of the composition of claim 1.

4. A cosmetic kit useful for improving the appearance of skin or hair, comprising: a) a first component comprising:

(i) from about 0.1 % to about 60%, by weight of the first component, of an inorganic colloid sol comprising a dispersion of an inorganic colloid in a polar carrier, wherein the inorganic colloid has a Tg of greater than 25°C; and

(ii) from about 10% to about 90% of a carrier; and b) a second component comprising:

(i) from about 0.1% to about 70%, by weight of the second component, of an adhesive elastomeric polymer having a Tg of less than 40°C; and (ii) from about 10% to about 90% of a carrier.