WO2002003942A3 - B complex vitamin compositions that protect against cellular damage caused by ultraviolet light - Google Patents

B complex vitamin compositions that protect against cellular damage caused by ultraviolet light Download PDF

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Publication number
WO2002003942A3
WO2002003942A3 PCT/CA2001/001006 CA0101006W WO0203942A3 WO 2002003942 A3 WO2002003942 A3 WO 2002003942A3 CA 0101006 W CA0101006 W CA 0101006W WO 0203942 A3 WO0203942 A3 WO 0203942A3
Authority
WO
WIPO (PCT)
Prior art keywords
vitamin
cells
light
alone
combination
Prior art date
Application number
PCT/CA2001/001006
Other languages
French (fr)
Other versions
WO2002003942A2 (en
Inventor
Barry J Barclay
Original Assignee
Planet Biotech Inc
Barry J Barclay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Planet Biotech Inc, Barry J Barclay filed Critical Planet Biotech Inc
Priority to AU2001272274A priority Critical patent/AU2001272274B2/en
Priority to EP01951290A priority patent/EP1299078A2/en
Priority to AU7227401A priority patent/AU7227401A/en
Priority to US09/900,064 priority patent/US7018623B2/en
Publication of WO2002003942A2 publication Critical patent/WO2002003942A2/en
Publication of WO2002003942A3 publication Critical patent/WO2002003942A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216—Solid or semisolid forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/673—Vitamin B group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/673—Vitamin B group
    • A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/06—Preparations for styling the hair, e.g. by temporary shaping or colouring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/10—Preparations for permanently dyeing the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/12—Preparations containing hair conditioners

Abstract

The present invention relates generally to the use of vitamin B12 (cobolamin or cyanocobalamin) alone or in combination with other photoprotective agents, including specifically other vitamins such as vitamin B9 (folic acid or folate) and vitamin B3 (niacin or niacinamide), or any chemical derivative of these vitamins and their salts, as a filter to protect cells against the damaging effects of ultraviolet (UV) light. The invention is, in one aspect, a method of reducing the rate of UV damage to cells exposed to a UV light source, by treating the cells with the vitamin composition, either alone or in combination with other photoprotective agents. Other aspects of the invention are compositions comprising effective amounts of vitamin B12 alone or in combination with other photoprotective agents including vitamin B9 and vitamin B3 and a pharmaceutically-acceptable carrier, that are useful in protecting cells, particularly skin cells, against the burning, genotoxic (mutagenic and carcinogenic), immunosuppressive and photoaging effects of UV light, especially sunlight. The invention has application as a UV light filter in oral preparations including tablets and drinks, topical creams, lotions, sprays, wipes and cosmetics. The invention also has application as a medicinal treatment for dermatological conditions caused by exposure to sunlight, such as actinic keratoses, photodermatitis, photo-induced (discoid) lupus erythematosus and the photosensitizing effects of a variety of drugs used commonly in clinical practice (e.g. certain antihistamines, ACE inhibitors, and antibiotics such as tetracycline).
PCT/CA2001/001006 2000-07-06 2001-07-06 B complex vitamin compositions that protect against cellular damage caused by ultraviolet light WO2002003942A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2001272274A AU2001272274B2 (en) 2000-07-06 2001-07-06 B complex vitamin compositions that protect against cellular damage caused by ultraviolet light
EP01951290A EP1299078A2 (en) 2000-07-06 2001-07-06 B complex vitamin compositions that protect against cellular damage caused by ultraviolet light
AU7227401A AU7227401A (en) 2000-07-06 2001-07-06 B complex vitamin compositions that protect against cellular damage caused by ultraviolet light
US09/900,064 US7018623B2 (en) 2000-07-06 2001-07-06 B complex vitamin compositions that protect against cellular damage caused by ultraviolet light

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA2,313,659 2000-07-06
CA002313659A CA2313659A1 (en) 2000-07-06 2000-07-06 B complex vitamin compositions that protect against cellular damage caused by ultraviolet light

Publications (2)

Publication Number Publication Date
WO2002003942A2 WO2002003942A2 (en) 2002-01-17
WO2002003942A3 true WO2002003942A3 (en) 2002-05-02

Family

ID=4166676

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2001/001006 WO2002003942A2 (en) 2000-07-06 2001-07-06 B complex vitamin compositions that protect against cellular damage caused by ultraviolet light

Country Status (5)

Country Link
US (1) US7018623B2 (en)
EP (1) EP1299078A2 (en)
AU (2) AU7227401A (en)
CA (1) CA2313659A1 (en)
WO (1) WO2002003942A2 (en)

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DE10130846A1 (en) * 2001-06-28 2003-01-16 Regeneratio Pharma Ag Use of corrinoids for use in skin diseases
JP2005525348A (en) * 2002-02-21 2005-08-25 ソシエテ デ プロデユイ ネツスル ソシエテ アノニム Photoprotective orally administrable composition for skin
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Also Published As

Publication number Publication date
CA2313659A1 (en) 2002-01-06
WO2002003942A2 (en) 2002-01-17
AU2001272274B2 (en) 2007-01-18
AU7227401A (en) 2002-01-21
US20020035087A1 (en) 2002-03-21
EP1299078A2 (en) 2003-04-09
US7018623B2 (en) 2006-03-28

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