US3154075A - Vaginal applicator - Google Patents

Vaginal applicator Download PDF

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Publication number
US3154075A
US3154075A US66831A US6683160A US3154075A US 3154075 A US3154075 A US 3154075A US 66831 A US66831 A US 66831A US 6683160 A US6683160 A US 6683160A US 3154075 A US3154075 A US 3154075A
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tube
valve stem
extremity
applicator
vaginal
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US66831A
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Charles L Weckesser
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Warner Chilcott Pharmaceuticals Inc
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Norwich Pharmacal Co
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body

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  • FIG.5 VAGINAL APPLICATOR Filed NOV. 2, 1960 FIGA FIG.5
  • This invention relates to a vaginal applicator designed for use with pressurized containers. More particularly, this invention relates to a vaginal applicator for such preparations as medicated antiseptics, deodorants, and cleansing fluids of varied viscosity.
  • the object of this invention is to provide a neat, economical and more eflicient means of administering fluids within the vaginal tract.
  • Virtue of the present invention all forms of fluid and semi-fluid vaginal preparations ranging from viscous creams through liquids and aerated foams may be administered directly from a pressurized container without danger or excessive waste.
  • pressurized containers have not been widely used for the packaging of vaginal preparations because of the danger of a possible build-up of excessive and harmful pressure within the vaginal tract.
  • the vaginal applica tor of this invention eliminates this hazard by venting any excessive pressure built up in the vaginal tract during use.
  • Another advantage inherent in the applicator of this invention is the fact that the applicator may be easily removed from the container for rinsing and storage between use.
  • the vaginal applicator of this invention may be used with any pressurized container having a side or top actuated valve mechanism.
  • Side actuated valve mechanisms are defined herein as those valves which are opened by simply moving the top of the valve stem to either side, i.e., by applying a force in a direction perpendicular to the valve stem opening.
  • the top actuated valve mechanism is distinguished from the side actuated valve in that the valve is opened by force applied directly opposite the direction of the valve stem extension.
  • Both the side and top actuated pressurized containers are self-sealing when the external force upon the valve stem is released. These two types of pressurized containers are well known in the art and are available commercially.
  • FIGURE 1 represents a side or plan view of the applicator attached to a standard pressurized container (shown by broken lines).
  • FIGURE 2 represents a front View of the applicator shown in FIGURE 1 above.
  • FIGURE 3 represents the side or plan view of a preferred design for the applicator of this invention.
  • FIGURE 4 is a front view of the applicator as shown in FIGURE 3.
  • FIGURE 5 is a transverse section of the applicator on the lines 5-5 of FIGURE 3 showing the multiple openings 7 in the shell 5 adjacent the butt portion of the tube.
  • the tapered tip portion 1 and middle portion 2 of the substantially cylindrical hollow tube 3 are designed for insertion into the vaginal tract.
  • the tip and middle portion of the tube 3 possess relatively large horizontal grooves 14 as a means of venting any pressure built up Within the vaginal tract during use.
  • the butt portion 17 of the elongated tube 3, i.e. the cap or knob extremity of tube 3 which is provided with a hollow interior adapted to receive and hold securely and "ice snugly the valve stem 16 of container 20, in a position such that the pressurized fluid held in the container 20 is forced upon its release, directly into and through tube 3, is provided with a single external opening at a right angle to, and contiguous with, the opening 15 of the tube 3.
  • the butt portion is also provided with a rounded concave top member 4 upon which finger pressure may be exerted in a downward or side-wise motion to eflect opening of the self-closing, valve stem 16 actuated, pressurized container.
  • the butt portion 17, as depicted in FIGURES l and 3, is mounted on the externally extending valve stem 16, which projects from container 20.
  • the cylindrical hollow tube 3 having a tip 1 and middle portion 2 is surrounded by a tapered shell 5 having an internal diameter substantially larger than the external diameter of said tube.
  • the tapered shell defines multiple openings 6 and 7, at opposite ends of the shell 5 for venting any pressure built up in the vaginal tract during use.
  • the butt portion 17 of the tube 3 has an external opening at a right angle to, and contiguous with, the tube opening 15.
  • the butt portion 17 is equipped with a rounded concave top member 4 adapted to receive finger pressure as is the butt portion of the applicator of FIGURE 1.
  • a vaginal applicator for mounting on the external valve stem of a pressurized fluid container, said applicator comprising an elongated tube having a first tapered ex tremity and a second extremity adaptable to be mounted on said valve stem in activating relationship thereto, said tube having a continuous opening therein from said first extremity to the valve stem mounting in the second extremity and means for controlling the flow of fluids from said container through said valve stem into said continuous opening, said tube having a plurality of peripheral longitudinal grooves parallel to said continuous opening and extending from said first extremity towards and adjacent to said second extremity to permit the excess pressure built up in the vaginal tract to be vented along said grooves.
  • a vaginal applicator for mounting on the external valve stem of a pressurized fluid container, said applicator comprising an elongated first tube having a first extremity, and a second extremity adaptable to be mounted on said valve stem in activating relationship thereto, a continuous opening extending from said first extremity to the valve stem mounting in the second extremity, means for controlling the flow of fluids from said container through said valve stem into said continuous opening, and an elongated tubular shell concentrically mounted on, extending substantially the length of and spaced from, said first tube, said shell having a tapered extremity positioned adjacent to and joining said first extremity of said tube, the tapered extremity being provided with a plurality of openings to permit the pressure built up within the vaginal tract to be vented through the space between said tube and said shell.

Description

1964 c. L. WECKESSER 3,154,075
VAGINAL APPLICATOR Filed NOV. 2, 1960 FIGA FIG.5
INVENTOR.
CHARLES L.WECKESSER AT TO RN EY United States Patent York Filed Nov. 2, 1960, Ser. No. 66,831 2 Claims. (Cl. 128-240) This invention relates to a vaginal applicator designed for use with pressurized containers. More particularly, this invention relates to a vaginal applicator for such preparations as medicated antiseptics, deodorants, and cleansing fluids of varied viscosity.
The object of this invention is to provide a neat, economical and more eflicient means of administering fluids within the vaginal tract. By Virtue of the present invention, all forms of fluid and semi-fluid vaginal preparations ranging from viscous creams through liquids and aerated foams may be administered directly from a pressurized container without danger or excessive waste. In the past, pressurized containers have not been widely used for the packaging of vaginal preparations because of the danger of a possible build-up of excessive and harmful pressure within the vaginal tract. The vaginal applica tor of this invention eliminates this hazard by venting any excessive pressure built up in the vaginal tract during use. Another advantage inherent in the applicator of this invention is the fact that the applicator may be easily removed from the container for rinsing and storage between use.
The vaginal applicator of this invention may be used with any pressurized container having a side or top actuated valve mechanism. Side actuated valve mechanisms are defined herein as those valves which are opened by simply moving the top of the valve stem to either side, i.e., by applying a force in a direction perpendicular to the valve stem opening. A more detailed description of a side actuated valve mechanism is given in copending U.S. patent application SN. 39,519 filed June 29, 1960 now abandoned. The top actuated valve mechanism is distinguished from the side actuated valve in that the valve is opened by force applied directly opposite the direction of the valve stem extension. Both the side and top actuated pressurized containers are self-sealing when the external force upon the valve stem is released. These two types of pressurized containers are well known in the art and are available commercially.
FIGURE 1 represents a side or plan view of the applicator attached to a standard pressurized container (shown by broken lines).
FIGURE 2 represents a front View of the applicator shown in FIGURE 1 above.
FIGURE 3 represents the side or plan view of a preferred design for the applicator of this invention.
FIGURE 4 is a front view of the applicator as shown in FIGURE 3.
FIGURE 5 is a transverse section of the applicator on the lines 5-5 of FIGURE 3 showing the multiple openings 7 in the shell 5 adjacent the butt portion of the tube.
The present invention may be more fully understood by reference to the attached drawings.
In FIGURE 1 the tapered tip portion 1 and middle portion 2 of the substantially cylindrical hollow tube 3 are designed for insertion into the vaginal tract. The tip and middle portion of the tube 3 possess relatively large horizontal grooves 14 as a means of venting any pressure built up Within the vaginal tract during use. The butt portion 17 of the elongated tube 3, i.e. the cap or knob extremity of tube 3 which is provided with a hollow interior adapted to receive and hold securely and "ice snugly the valve stem 16 of container 20, in a position such that the pressurized fluid held in the container 20 is forced upon its release, directly into and through tube 3, is provided with a single external opening at a right angle to, and contiguous with, the opening 15 of the tube 3. The butt portion is also provided with a rounded concave top member 4 upon which finger pressure may be exerted in a downward or side-wise motion to eflect opening of the self-closing, valve stem 16 actuated, pressurized container. The butt portion 17, as depicted in FIGURES l and 3, is mounted on the externally extending valve stem 16, which projects from container 20.
In FIGURE 3 the cylindrical hollow tube 3 having a tip 1 and middle portion 2 is surrounded by a tapered shell 5 having an internal diameter substantially larger than the external diameter of said tube. The tapered shell defines multiple openings 6 and 7, at opposite ends of the shell 5 for venting any pressure built up in the vaginal tract during use. The butt portion 17 of the tube 3 has an external opening at a right angle to, and contiguous with, the tube opening 15. The butt portion 17 is equipped with a rounded concave top member 4 adapted to receive finger pressure as is the butt portion of the applicator of FIGURE 1.
The above description is intended to more fully describe the nature of this invention and is not intended to limit or restrict this invention in any Way.
What is claimed is:
1. A vaginal applicator for mounting on the external valve stem of a pressurized fluid container, said applicator comprising an elongated tube having a first tapered ex tremity and a second extremity adaptable to be mounted on said valve stem in activating relationship thereto, said tube having a continuous opening therein from said first extremity to the valve stem mounting in the second extremity and means for controlling the flow of fluids from said container through said valve stem into said continuous opening, said tube having a plurality of peripheral longitudinal grooves parallel to said continuous opening and extending from said first extremity towards and adjacent to said second extremity to permit the excess pressure built up in the vaginal tract to be vented along said grooves.
2. A vaginal applicator for mounting on the external valve stem of a pressurized fluid container, said applicator comprising an elongated first tube having a first extremity, and a second extremity adaptable to be mounted on said valve stem in activating relationship thereto, a continuous opening extending from said first extremity to the valve stem mounting in the second extremity, means for controlling the flow of fluids from said container through said valve stem into said continuous opening, and an elongated tubular shell concentrically mounted on, extending substantially the length of and spaced from, said first tube, said shell having a tapered extremity positioned adjacent to and joining said first extremity of said tube, the tapered extremity being provided with a plurality of openings to permit the pressure built up within the vaginal tract to be vented through the space between said tube and said shell.
References Cited in the file of this patent UNITED STATES PATENTS 1,531,213 Nimmer Mar. 24, 1925 1,638,532 Kallmeyer Aug. 9, 1927 2,826,194 Golden Mar. 11, 1958 2,870,767 Bowen Jan. 27, 1959 3,067,784 Gorman Dec. 11, 1962 FOREIGN PATENTS 106,028 Australia Dec. 15, 1938

Claims (1)

1. A VAGINAL APPLICATOR FOR MOUNTING ON THE EXTERNAL VALVE STEM OF A PRESSURIZED FLUID CONTAINER, SAID APPLICATOR COMPRISING AN ELONGATED TUBE HAVING A FIRST TAPERED EXTREMITY AND A SECOND EXTREMITY ADAPTABLE TO BE MOUNTED ON SAID VALVE STEM IN ACTIVATING RELATIONSHIP THERETO, SAID TUBE HAVING A CONTINUOUS OPENING THEREIN FROM SAID FIRST EXTREMITY TO THE VALVE STEM MOUNTING IN THE SECOND EXTREMITY AND MEANS FOR CONTROLLING THE FLOW OF FLUIDS FROM SAID CONTAINER THROUGH SAID VALVE STEM INTO SAID CONTINUOUS OPENING, SAID TUBE HAVING A PLURALITY OF PE-
US66831A 1960-11-02 1960-11-02 Vaginal applicator Expired - Lifetime US3154075A (en)

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Cited By (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3186645A (en) * 1964-02-10 1965-06-01 Roberta R Eberlein Spray nozzle for pressurized containers
US3228396A (en) * 1962-10-18 1966-01-11 Albert L Potts Vaginal syringe
US4354638A (en) * 1980-04-25 1982-10-19 Bristol-Myers Company Spiral actuator for aerosol powdered suspension product
US4402684A (en) * 1981-09-16 1983-09-06 The Kendall Company Cannula with soft tip
US5307964A (en) * 1992-01-31 1994-05-03 John B. Toth Aerosol extension
US6067936A (en) * 1998-06-27 2000-05-30 Margulis; David J. Method and apparatus for resuscitation of aquatic animals
US6305065B1 (en) 1997-12-19 2001-10-23 Illinois Tool Works Inc. Method of assembling roof decking to an underlying substrate
US20070069046A1 (en) * 2005-04-19 2007-03-29 Foamix Ltd. Apparatus and method for releasing a measure of content from a plurality of containers
US20090068118A1 (en) * 2007-09-04 2009-03-12 Foamix Ltd. Device for delivery of a foamable composition
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US20110178162A1 (en) * 2005-10-14 2011-07-21 Medical University Of South Carolina Targeting pax2 for the induction of defb1-mediated tumor immunity and cancer therapy
US8114385B2 (en) 2003-08-04 2012-02-14 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
US8343945B2 (en) 2007-12-07 2013-01-01 Foamix Ltd. Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
US8435498B2 (en) 2002-10-25 2013-05-07 Foamix Ltd. Penetrating pharmaceutical foam
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
US8518376B2 (en) 2007-12-07 2013-08-27 Foamix Ltd. Oil-based foamable carriers and formulations
US8618081B2 (en) 2009-10-02 2013-12-31 Foamix Ltd. Compositions, gels and foams with rheology modulators and uses thereof
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
US8709385B2 (en) 2008-01-14 2014-04-29 Foamix Ltd. Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses
US8722021B2 (en) 2002-10-25 2014-05-13 Foamix Ltd. Foamable carriers
US8795635B2 (en) 2006-11-14 2014-08-05 Foamix Ltd. Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US8978936B2 (en) 2010-07-12 2015-03-17 Foamix Pharmaceuticals Ltd. Apparatus and method for releasing a unit dose of content from a container
US9072667B2 (en) 2009-07-29 2015-07-07 Foamix Pharmaceuticals Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
US9167813B2 (en) 2009-07-29 2015-10-27 Foamix Pharmaceuticals Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US9320705B2 (en) 2002-10-25 2016-04-26 Foamix Pharmaceuticals Ltd. Sensation modifying topical composition foam
US9439857B2 (en) 2007-11-30 2016-09-13 Foamix Pharmaceuticals Ltd. Foam containing benzoyl peroxide
US9539208B2 (en) 2002-10-25 2017-01-10 Foamix Pharmaceuticals Ltd. Foam prepared from nanoemulsions and uses
US9622947B2 (en) 2002-10-25 2017-04-18 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
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USD903110S1 (en) 2019-01-09 2020-11-24 Board Of Regents, The University Of Texas System Gel applicator for magnetic resonance imaging

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1531213A (en) * 1921-01-25 1925-03-24 Edward W Nimmer Syringe
US1638532A (en) * 1924-02-02 1927-08-09 Kallmeyer Ernst Syringe head
US2826194A (en) * 1955-11-07 1958-03-11 Golden Seymour Liquid applicator
US2870767A (en) * 1957-07-12 1959-01-27 Max E Bowen Pressurized douche applicator
US3067784A (en) * 1960-04-14 1962-12-11 Esta Medical Lab Inc Adapter connecting aerosol container valve stem to dispenser for filling said dispenser

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1531213A (en) * 1921-01-25 1925-03-24 Edward W Nimmer Syringe
US1638532A (en) * 1924-02-02 1927-08-09 Kallmeyer Ernst Syringe head
US2826194A (en) * 1955-11-07 1958-03-11 Golden Seymour Liquid applicator
US2870767A (en) * 1957-07-12 1959-01-27 Max E Bowen Pressurized douche applicator
US3067784A (en) * 1960-04-14 1962-12-11 Esta Medical Lab Inc Adapter connecting aerosol container valve stem to dispenser for filling said dispenser

Cited By (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3228396A (en) * 1962-10-18 1966-01-11 Albert L Potts Vaginal syringe
US3186645A (en) * 1964-02-10 1965-06-01 Roberta R Eberlein Spray nozzle for pressurized containers
US4354638A (en) * 1980-04-25 1982-10-19 Bristol-Myers Company Spiral actuator for aerosol powdered suspension product
US4402684A (en) * 1981-09-16 1983-09-06 The Kendall Company Cannula with soft tip
US5307964A (en) * 1992-01-31 1994-05-03 John B. Toth Aerosol extension
US6305065B1 (en) 1997-12-19 2001-10-23 Illinois Tool Works Inc. Method of assembling roof decking to an underlying substrate
US6067936A (en) * 1998-06-27 2000-05-30 Margulis; David J. Method and apparatus for resuscitation of aquatic animals
US6250253B1 (en) * 1998-06-27 2001-06-26 David Jonathan Margulis Method and apparatus for resuscitation of aquatic animals
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
US9622947B2 (en) 2002-10-25 2017-04-18 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US9713643B2 (en) 2002-10-25 2017-07-25 Foamix Pharmaceuticals Ltd. Foamable carriers
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US8722021B2 (en) 2002-10-25 2014-05-13 Foamix Ltd. Foamable carriers
US9539208B2 (en) 2002-10-25 2017-01-10 Foamix Pharmaceuticals Ltd. Foam prepared from nanoemulsions and uses
US9492412B2 (en) 2002-10-25 2016-11-15 Foamix Pharmaceuticals Ltd. Penetrating pharmaceutical foam
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
US10322085B2 (en) 2002-10-25 2019-06-18 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US9320705B2 (en) 2002-10-25 2016-04-26 Foamix Pharmaceuticals Ltd. Sensation modifying topical composition foam
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US8435498B2 (en) 2002-10-25 2013-05-07 Foamix Ltd. Penetrating pharmaceutical foam
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US8741265B2 (en) 2002-10-25 2014-06-03 Foamix Ltd. Penetrating pharmaceutical foam
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US10265404B2 (en) 2009-10-02 2019-04-23 Foamix Pharmaceuticals Ltd. Compositions, gels and foams with rheology modulators and uses thereof
US8992896B2 (en) 2009-10-02 2015-03-31 Foamix Pharmaceuticals Ltd. Topical tetracycline compositions
US8871184B2 (en) 2009-10-02 2014-10-28 Foamix Ltd. Topical tetracycline compositions
US10086080B2 (en) 2009-10-02 2018-10-02 Foamix Pharmaceuticals Ltd. Topical tetracycline compositions
US10029013B2 (en) 2009-10-02 2018-07-24 Foamix Pharmaceuticals Ltd. Surfactant-free, water-free formable composition and breakable foams and their uses
US8865139B1 (en) 2009-10-02 2014-10-21 Foamix Pharmaceuticals Ltd. Topical tetracycline compositions
US9675700B2 (en) 2009-10-02 2017-06-13 Foamix Pharmaceuticals Ltd. Topical tetracycline compositions
US10463742B2 (en) 2009-10-02 2019-11-05 Foamix Pharmaceuticals Ltd. Topical tetracycline compositions
US10517882B2 (en) 2009-10-02 2019-12-31 Foamix Pharmaceuticals Ltd. Method for healing of an infected acne lesion without scarring
US10137200B2 (en) 2009-10-02 2018-11-27 Foamix Pharmaceuticals Ltd. Surfactant-free water-free foamable compositions, breakable foams and gels and their uses
US10610599B2 (en) 2009-10-02 2020-04-07 Foamix Pharmaceuticals Ltd. Topical tetracycline compositions
US8945516B2 (en) 2009-10-02 2015-02-03 Foamix Pharmaceuticals Ltd. Surfactant-free water-free foamable compositions, breakable foams and gels and their uses
US10821187B2 (en) 2009-10-02 2020-11-03 Foamix Pharmaceuticals Ltd. Compositions, gels and foams with rheology modulators and uses thereof
US10835613B2 (en) 2009-10-02 2020-11-17 Foamix Pharmaceuticals Ltd. Compositions, gels and foams with rheology modulators and uses thereof
US8618081B2 (en) 2009-10-02 2013-12-31 Foamix Ltd. Compositions, gels and foams with rheology modulators and uses thereof
US10967063B2 (en) 2009-10-02 2021-04-06 Vyne Therapeutics Inc. Surfactant-free, water-free formable composition and breakable foams and their uses
US10946101B2 (en) 2009-10-02 2021-03-16 Vyne Therapeutics Inc. Surfactant-free water-free foamable compositions, breakable foams and gels and their uses
US8978936B2 (en) 2010-07-12 2015-03-17 Foamix Pharmaceuticals Ltd. Apparatus and method for releasing a unit dose of content from a container
US9463919B2 (en) 2010-07-12 2016-10-11 Foamix Pharmaceuticals Ltd. Apparatus and method for releasing a unit dose of content from a container
US10849847B2 (en) 2016-09-08 2020-12-01 Foamix Pharamaceuticals Ltd. Compositions and methods for treating rosacea and acne
US10398641B2 (en) 2016-09-08 2019-09-03 Foamix Pharmaceuticals Ltd. Compositions and methods for treating rosacea and acne
US11324691B2 (en) 2016-09-08 2022-05-10 Journey Medical Corporation Compositions and methods for treating rosacea and acne
USD903110S1 (en) 2019-01-09 2020-11-24 Board Of Regents, The University Of Texas System Gel applicator for magnetic resonance imaging

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