CN104436140A - Medicine for treating beriberi heart disease - Google Patents
Medicine for treating beriberi heart disease Download PDFInfo
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- CN104436140A CN104436140A CN201410780891.7A CN201410780891A CN104436140A CN 104436140 A CN104436140 A CN 104436140A CN 201410780891 A CN201410780891 A CN 201410780891A CN 104436140 A CN104436140 A CN 104436140A
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Classifications
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Abstract
The invention discloses a medicine for treating beriberi heart disease, belongs to the field of medicines, and in particular relates to a composition for treating the beriberi heart disease. The medicine disclosed by the invention is characterized by comprising the following Chinese herbal medicines in parts by weight: 10-15 parts of orange peel, 6-9 parts of radix ophiopogonis, 5-8 parts of radix bupleuri, 8-12 parts of bighead atractylodes rhizome, 8-12 parts of antelope's horn, 10-15 parts of fructus evodiae, 15-20 parts of Pinellia ternata, 5-10 parts of white poria, 8-10 parts of the root of bidentate achyranthes, 12-15 parts of rhizome of rehmannia, 5-8 parts of cassia twig, 6-9 parts of cortex acanthopanacis, 15-20 parts of the root of red-rooted salvia, 8-12 parts of astragalus, 10-15 parts of radix polygonati officinalis, 9-12 parts of honey-fried licorice root, 5-7 parts of fresh ginger and 5-7 parts of Chinese-dates. The traditional Chinese medicine is prepared according to a traditional Chinese medicine decoction method and has an obvious curative effect on beriberi heart disease if taken together with vitamin B1, the effective rate is 100 percent, and the cure rate is over 98 percent.
Description
Technical field
The invention belongs to medical domain, be specifically related to a kind of prescription medicine for the treatment of beriberi cardiopathy.
Background technology
Beriberi cardiopathy is that vitamin B1 is serious and lack the one high discharge capacity type heart disease caused for a long time; Primary disease is that cyanosis on the face and lips, staring spells, nausea and vomiting etc. are the vitamin B1 deficiency of feature with also had palpitation asthma.Pathogeny, vitamin B1 participates in the metabolic process of saccharide as a kind of coenzyme, in intermediate supersession oxidizing process, play important catalytic action, the B1 that is deficient in vitamin can make acetone acid be difficult to enter Rhizoma Sparganii acid circulation and be oxidized, and thus in blood, the concentration of acetone acid and predecessor's lactic acid thereof increases, make arteriolar dilatation around, peripheral resistance lowers, therefore diastolic pressure declines, and pulse pressure increases, venous return increases, and heart burden increases.
Tcm diagnosis is for this reason sick to be entered from foot interior by rheumatism poison, is fought mutually with visceral-qi, and knot is poly-not to fall apart, therefore abdominal distnetion is anxious also; Show as cardiopalmus asthma, cyanosis on the face and lips, edema of lower limbs, apathetic, limbs are heavy, and pale tongue is fat, white, slippery and moist fur, soft pulse.
This disease of western medical treatment is independent vitimin supplement B1, but to lack situation ill caused by vitamin B1 in food little due to simple at present, occur that mostly disease is due to body constitution difference, the medicine of the beriberi cardiopathy that the bad or Chronic consumptions of gastrointestinal absorption causes, simple vitimin supplement B1 cures the symptoms, not the disease.
Summary of the invention
For overcoming the above problems, the invention provides a kind of medicine of energy treating both the principal and secondary aspects of a disease treatment beriberi cardiopathy.
Treatment by Chinese herbs beriberi cardiopathy is with removing dampness the turbid descending, and stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, blood circulation promoting and blood stasis dispelling, rousing oneself heart-yang is the rule for the treatment of.
For realizing above curative effect, the present invention includes following Chinese herbal medicine: Pericarpium Citri tangerinae, Radix Ophiopogonis, Radix Bupleuri, the Rhizoma Atractylodis Macrocephalae, Cornu Saigae Tataricae, Fructus Evodiae, the Rhizoma Pinelliae, Poria, Radix Achyranthis Bidentatae, the Radix Rehmanniae, Ramulus Cinnamomi, Cortex Acanthopancis, Radix Salviae Miltiorrhizae, the Radix Astragali, Rhizoma Polygonati Odorati, Radix Glycyrrhizae Preparata, Rhizoma Zingiberis Recens, Fructus Jujubae, it is characterized in that: each Chinese medicine weight portion is Pericarpium Citri tangerinae 10-15 part, Radix Ophiopogonis 6-9 part, Radix Bupleuri 5-8 part, Rhizoma Atractylodis Macrocephalae 8-12 part, Cornu Saigae Tataricae 8-12 part, Fructus Evodiae, 10-15 part, Rhizoma Pinelliae 15-20 part, Poria 5-10 part, Radix Achyranthis Bidentatae 8-10 part, Radix Rehmanniae 12-15 part, Ramulus Cinnamomi 5-8 part, Cortex Acanthopancis 6-9 part, Radix Salviae Miltiorrhizae 15-20 part, Radix Astragali 8-12 part, Rhizoma Polygonati Odorati 10-15 part, Radix Glycyrrhizae Preparata 9-12 part, Rhizoma Zingiberis Recens 5-7 part, Fructus Jujubae 5-7 part.
Preferably, optimum weight part of above-mentioned formula is: Pericarpium Citri tangerinae 12 parts, Radix Ophiopogonis 8 parts, Radix Bupleuri 6 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Cornu Saigae Tataricae 8 parts, Fructus Evodiae 12 parts, the Rhizoma Pinelliae 20 parts, Poria 8 parts, Radix Achyranthis Bidentatae 8 parts, 15 parts, the Radix Rehmanniae, Ramulus Cinnamomi 7 parts, Cortex Acanthopancis 8 parts, Radix Salviae Miltiorrhizae 15 parts, the Radix Astragali 10 parts, Rhizoma Polygonati Odorati 12 parts, Radix Glycyrrhizae Preparata 12 parts, 5 parts, Rhizoma Zingiberis Recens, 5 parts, Fructus Jujubae.
Wherein said: Pericarpium Citri tangerinae, pungent, the micro-hardship of nature and flavor, temperature, return spleen, lung meridian, having and regulating the flow of vital energy in tune, effect of drying dampness to eliminate phlegm effect.
Radix Ophiopogonis, sweet, the micro-hardship of nature and flavor, to be slightly cold, to return lung, the heart, stomach warp, there is effect of nourishing YIN and moistening the lung, reinforcing stomach reg fluid, the relieving restlessness that clears away heart-fire.
Radix Bupleuri, nature and flavor are bitter, pungent, be slightly cold, GUIXIN, liver, gallbladder, tri-jiao channel, have that evacuation is brought down a fever, effect of dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.
The Rhizoma Atractylodis Macrocephalae, nature and flavor are bitter, sweet, warm, return spleen, stomach warp, have air making-up and spleen enlivening, dampness diuretic, hidroschesis, antiabortive effect.
Cornu Saigae Tataricae, nature and flavor are salty, cold, return liver, heart channel, have endogenous wind stopping relieving convulsion, effect that suppressing the hyperactive liver and subsiding YANG, liver heat removing and eyesight improving, pyretic toxicity send out speckle.
Fructus Evodiae, nature and flavor are bitter, pungent, return liver, spleen, stomach warp, have effect of dispersing cold for relieving pain, the soothing the liver therapeutic method to keep the adverse QI flowing downwards, dampness sending down the abnormal ascending QI.
The Rhizoma Pinelliae, nature and flavor are pungent, warm, return spleen, stomach, lung meridian, have effect of drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.
Poria, nature and flavor are sweet, light, flat, GUIXIN, spleen, kidney channel, have effect of promoting diuresis to eliminate damp pathogen, spleen-benefiting mind-tranquilizing.
Radix Achyranthis Bidentatae, nature and flavor are bitter, sour, flat, return liver, kidney channel, have blood circulation promoting and blood stasis dispelling, invigorating the liver and kidney, bone and muscle strengthening, relieving stranguria by diuresis, effect of conducting blood to flow downwards.
The Radix Rehmanniae, nature and flavor are sweet, bitter, cold, and GUIXIN, liver, kidney channel, have effect of clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting.
Ramulus Cinnamomi, nature and flavor are pungent, sweet, warm, GUIXIN, lung, urinary bladder channel, have effect of relieving the exterior syndrome by diaphoresis, warming the meridian for promoting the flow of YANG QI.
Cortex Acanthopancis, nature and flavor are pungent, bitter, sweet, warm, return liver, kidney channel, have effect of wind-damp dispelling, strengthening bone and muscle, Fructus Alpiniae Oxyphyllae, diuretic.
Radix Salviae Miltiorrhizae, nature and flavor are slightly cold, hardship, and GUIXIN, Liver Channel, have effect of promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing, the relieving restlessness that clears away heart-fire.
The Radix Astragali, nature and flavor are sweet, tepor, return spleen, lung meridian, have effect of stomach reinforcing consolidating superficial resistance, polishing yang invigorating, promoting pus discharge and tissue regeneration strengthening, inducing diuresis to remove edema.
Rhizoma Polygonati Odorati, nature and flavor are sweet, flat, attach to the lung and stomach meridians, have nourishing YIN and moistening the lung, the effect of nourishing the stomach of promoting the production of body fluid.
Radix Glycyrrhizae Preparata, nature and flavor are sweet, flat, enter the heart, lung, spleen, stomach warp, have invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, effect of coordinating the actions of various ingredients in a prescription.
Rhizoma Zingiberis Recens, nature and flavor are pungent, tepor, return lung spleen channel, have effect of relieving the exterior syndrome by diaphoresis, warming middle-JIAO to stop vomiting, warming the lung to relieve cough.
Fructus Jujubae, nature and flavor are sweet, warm, return spleen, stomach warp, have invigorating the spleen and replenishing QI, effect of nourishing blood to tranquillize the mind, the mitigation property of medicine.
Described Pericarpium Citri tangerinae, Radix Bupleuri, Radix Achyranthis Bidentatae, the Radix Astragali, Rhizoma Polygonati Odorati, Radix Ophiopogonis, the Rhizoma Atractylodis Macrocephalae, having and regulating the flow of vital energy in tune, elevate a turnable ladder yang-energy, invigorating the liver and kidney, bone and muscle strengthening, stomach reinforcing consolidating superficial resistance, polishing yang invigorating, promoting pus discharge and tissue regeneration strengthening, effect of air making-up and spleen enlivening, coordinate Cornu Saigae Tataricae, Fructus Evodiae, the Rhizoma Pinelliae, Poria, the Radix Rehmanniae, Ramulus Cinnamomi, Cortex Acanthopancis, Radix Salviae Miltiorrhizae, endogenous wind stopping relieving convulsion, liver heat removing and eyesight improving, stasis-dispelling and pain-killing, the soothing the liver therapeutic method to keep the adverse QI flowing downwards, drying dampness to eliminate phlegm, dissolving lump and resolving mass, relieving the exterior syndrome by diaphoresis, clear away heart-fire effect of relieving restlessness, by Radix Glycyrrhizae Preparata, invigorating the spleen and replenishing QI, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, be equipped with Rhizoma Zingiberis Recens, Fructus Jujubae is for drawing, warming the lung to relieve cough, invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, relax the property of medicine, there is removing dampness the turbid descending, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, blood circulation promoting and blood stasis dispelling, rouse oneself effect of heart-yang.
Above-mentioned Chinese medicine, according to Traditional medicine infusion method, obtains herb liquid, is divided into two parts, sooner or later each a decoction being taken warmly, 6th is a course for the treatment of, coordinates and takes vitamin B1, for treatment beriberi cardiopathy successful, verify according to clinical application for many years: effective percentage 100%, cure rate more than 98%.
Detailed description of the invention
The present invention will be further described in conjunction with the embodiments.
Embodiment, treatment beriberi cardiopathy medicine, it is characterized in that weighting raw materials thing according to the following ratio: Pericarpium Citri tangerinae 10-15 part, Radix Ophiopogonis 6-9 part, Radix Bupleuri 5-8 part, Rhizoma Atractylodis Macrocephalae 8-12 part, Cornu Saigae Tataricae 8-12 part, Fructus Evodiae 10-15 part, Rhizoma Pinelliae 15-20 part, Poria 5-10 part, Radix Achyranthis Bidentatae 8-10 part, Radix Rehmanniae 12-15 part, Ramulus Cinnamomi 5-8 part, Cortex Acanthopancis 6-9 part, Radix Salviae Miltiorrhizae 15-20 part, Radix Astragali 8-12 part, Rhizoma Polygonati Odorati 10-15 part, Radix Glycyrrhizae Preparata 9-12 part, Rhizoma Zingiberis Recens 5-7 part, Fructus Jujubae 5-7 part.
Further, as preferred plan drug ratio: Pericarpium Citri tangerinae 12 parts, Radix Ophiopogonis 8 parts, Radix Bupleuri 6 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Cornu Saigae Tataricae 8 parts, Fructus Evodiae 12 parts, the Rhizoma Pinelliae 20 parts, Poria 8 parts, Radix Achyranthis Bidentatae 8 parts, 15 parts, the Radix Rehmanniae, Ramulus Cinnamomi 7 parts, Cortex Acanthopancis 8 parts, Radix Salviae Miltiorrhizae 15 parts, the Radix Astragali 10 parts, Rhizoma Polygonati Odorati 12 parts, Radix Glycyrrhizae Preparata 12 parts, 5 parts, Rhizoma Zingiberis Recens, 5 parts, Fructus Jujubae.
By the Rhizoma Zingiberis Recens in above-mentioned Chinese medicine formula, Fructus Jujubae cotton gauze parcel, putting into clear water soaks for subsequent use, Pericarpium Citri tangerinae, Radix Ophiopogonis, Radix Bupleuri, the Rhizoma Atractylodis Macrocephalae, Cornu Saigae Tataricae, Fructus Evodiae, the Rhizoma Pinelliae, Poria, Radix Achyranthis Bidentatae, the Radix Rehmanniae, Ramulus Cinnamomi, Cortex Acanthopancis, Radix Salviae Miltiorrhizae, the Radix Astragali, Rhizoma Polygonati Odorati, Radix Glycyrrhizae Preparata are put into clear water and soaked 60 minutes, put into after big fire is boiled Rhizoma Zingiberis Recens and Fructus Jujubae and soak clear water, little fire endures 30 minutes slowly, and drop goes out medicinal liquid; Big fire is boiled again to add cold water, and little fire endures 30 minutes slowly, and drop goes out medicinal liquid; United two into one by two medicinal liquids, fried about 300ML, is divided into two parts altogether, and every day is each portion heating decoction being taken warmly sooner or later, and within 6th, be a course for the treatment of, vitamin B1 is taken in period cooperation.2-3 the course for the treatment of specimen can cure beriberi cardiopathy, no longer recurs.
According to long-term clinical application, as follows to the patient outcomes of beriberi cardiopathy:
| Group | Treatment time | Number of cases | Recovery from illness | Effectively | Invalid | Effective percentage | Cure rate |
| Of the present invention group | 20-40 days | 50 | 49 | 1 | 0 | 100% | 98% |
| Matched group | 20-40 days | 50 | 26 | 15 | 9 | 82% | 52% |
During clinical practice, of the present invention group, while taking medicine of the present invention, take vitamin B1; Matched group, only takes vitamin B1.
By clinical practice, use effective percentage 100% of the present invention, cure rate more than 98%.
Treatment standard: cure: cardiopalmus is panted, cyanosis on the face and lips, staring spells, nausea and vomiting, fatigue is out of breath waits transference cure, pulse frequency is normal, blood pressure is normal, and percussion heart tone is normal, without signs such as hepatomegaly, hydrothorax, seroperitoneum and pericardial effusions, normally, nothing recurs for blood acetone acid content (normal value 57 ~ 125 μm of ol/L) and lactic acid concn; Tcm diagnosis, edema of lower limbs disappears, and limbs are flexible, and body of the tongue is ruddy, and tongue is without exception, and pulse-phase is normal.
Effective: weakness, fatigue, cardiopalmus, slightly out of breath, pulse frequency fast but rarely exceed 120 beats/min, blood pressure is low, pulse pressure difference increases, percussion relativecardiac dullness is normal, or gently expand to severe, single one or more of looking into sees hepatomegaly, hydrothorax, seroperitoneum and pericardial effusion sign, and Blood of Patients acetone acid content (normal value 57 ~ 125 μm of ol/L) or lactic acid concn slightly raise; Tcm diagnosis, edema of lower limbs alleviates, and limbs sense of heaviness slightly subtracts, and body of the tongue is ruddy, and tongue is whiten slightly, soft pulse.
Invalid: cardiopalmus asthma, cyanosis on the face and lips, staring spells, nausea and vomiting, cardiopalmus symptom out of breath are without change, there is anorexia, Nausea and vomiting, oliguria and peripheral edema in heart failure patient, pulse frequency is quick, blood pressure is low, pulse pressure difference increases, percussion relativecardiac dullness is abnormal, can look into and see hepatomegaly, hydrothorax, seroperitoneum and pericardial effusion sign, and Blood of Patients acetone acid content (normal value 57 ~ 125 μm of ol/L) and lactic acid concn raise; Tcm diagnosis, cardiopalmus is panted, cyanosis on the face and lips, edema of lower limbs, and apathetic, limbs are heavy, and pale tongue is fat, white, slippery and moist fur, soft pulse.
Model case.
1. side XX, man, 22 years old, patients is cardiopalmus, out of breath, Nausea and vomiting, oliguria and peripheral edema, health check-up positive sign is the performance that body circulation venous pressure is high, fast but rarely exceed 120 beats/min, blood pressure is low, but pulse pressure difference increases for pulse frequency, apex S3 gallop rhythm, pareordia mid systolic murmur, two base of lung moist rales, can look into and see hepatomegaly, hydrothorax, seroperitoneum and pericardial effusion sign, blood acetone acid content (normal value 57 ~ 125 μm of ol/L) and lactic acid concn raise, and make a definite diagnosis and suffer from beriberi cardiopathy.Through taking 3 courses for the treatment of of this formula Chinese medicine, vitamin B1 is taken in period cooperation, and above-mentioned symptom all disappears, without recurrence.
2. king X,, 43 years old, there is anorexia, Nausea and vomiting, oliguria and peripheral edema in female, blood pressure is low, pulse pressure difference increases, peripheral arterial audible and pistol-shot sound, and percussion relativecardiac dullness gently expands to severe, blood acetone acid content (normal value 57 ~ 125 μm of ol/L) and lactic acid concn raise, Electrocardiogram Feature is for showing as sinus tachycardia, and QRS ripple low-voltage, makes a definite diagnosis and suffer from beriberi cardiopathy.Through taking 3 courses for the treatment of of this formula Chinese medicine, vitamin B1 is taken in period cooperation, and suitably have a rest, above-mentioned symptom all disappears, then without recurrence.
Claims (2)
1. treat the medicine of beriberi cardiopathy
,comprise following Chinese herbal medicine: Pericarpium Citri tangerinae, Radix Ophiopogonis, Radix Bupleuri, the Rhizoma Atractylodis Macrocephalae, Cornu Saigae Tataricae, Fructus Evodiae, the Rhizoma Pinelliae, Poria, Radix Achyranthis Bidentatae, the Radix Rehmanniae, Ramulus Cinnamomi, Cortex Acanthopancis, Radix Salviae Miltiorrhizae, the Radix Astragali, Rhizoma Polygonati Odorati, Radix Glycyrrhizae Preparata, Rhizoma Zingiberis Recens, Fructus Jujubae, it is characterized in that: each Chinese medicine weight portion is Pericarpium Citri tangerinae 10-15 part, Radix Ophiopogonis 6-9 part, Radix Bupleuri 5-8 part, Rhizoma Atractylodis Macrocephalae 8-12 part, Cornu Saigae Tataricae 8-12 part, Fructus Evodiae, 10-15 part, Rhizoma Pinelliae 15-20 part, Poria 5-10 part, Radix Achyranthis Bidentatae 8-10 part, Radix Rehmanniae 12-15 part, Ramulus Cinnamomi 5-8 part, Cortex Acanthopancis 6-9 part, Radix Salviae Miltiorrhizae 15-20 part, Radix Astragali 8-12 part, Rhizoma Polygonati Odorati 10-15 part, Radix Glycyrrhizae Preparata 9-12 part, Rhizoma Zingiberis Recens 5-7 part, Fructus Jujubae 5-7 part.
2. the medicine for the treatment of beriberi cardiopathy according to claim 1, it is characterized in that: optimum weight part of above-mentioned Chinese medicine is, Pericarpium Citri tangerinae 12 parts, Radix Ophiopogonis 8 parts, Radix Bupleuri 6 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Cornu Saigae Tataricae 8 parts, Fructus Evodiae 12 parts, the Rhizoma Pinelliae 20 parts, Poria 8 parts, Radix Achyranthis Bidentatae 8 parts, 15 parts, the Radix Rehmanniae, Ramulus Cinnamomi 7 parts, Cortex Acanthopancis 8 parts, Radix Salviae Miltiorrhizae 15 parts, the Radix Astragali 10 parts, Rhizoma Polygonati Odorati 12 parts, Radix Glycyrrhizae Preparata 12 parts, 5 parts, Rhizoma Zingiberis Recens, 5 parts, Fructus Jujubae.
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| CN1403149A (en) * | 2002-10-24 | 2003-03-19 | 河北以岭医药研究院有限公司 | Medicines composition for treating chronic heart failure and its prepn |
| WO2009097512A1 (en) * | 2008-02-01 | 2009-08-06 | Innovative Drug Discovery Inc. | Herbal pharmaceutical compositions to treat inflammation and inflammation associated conditions and diseases |
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| CN1403149A (en) * | 2002-10-24 | 2003-03-19 | 河北以岭医药研究院有限公司 | Medicines composition for treating chronic heart failure and its prepn |
| WO2009097512A1 (en) * | 2008-02-01 | 2009-08-06 | Innovative Drug Discovery Inc. | Herbal pharmaceutical compositions to treat inflammation and inflammation associated conditions and diseases |
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| Title |
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| 洪用森等: "《中西医结合内科诊疗手册》", 31 May 1990, 浙江科学技术出版社 * |
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