WO2011133719A3 - Anti-viral compounds - Google Patents
Anti-viral compounds Download PDFInfo
- Publication number
- WO2011133719A3 WO2011133719A3 PCT/US2011/033322 US2011033322W WO2011133719A3 WO 2011133719 A3 WO2011133719 A3 WO 2011133719A3 US 2011033322 W US2011033322 W US 2011033322W WO 2011133719 A3 WO2011133719 A3 WO 2011133719A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- compounds
- viral compounds
- rig
- pathway
- viral infection
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D421/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms
- C07D421/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms containing two hetero rings
- C07D421/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Abstract
Disclosed herein are compounds and related compositions for the treatment of viral infection, including RNA viral infection, and compounds that can modulate the RIG-I pathway in vertebrate cells, including compounds that can activate the RIG-I pathway.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32754310P | 2010-04-23 | 2010-04-23 | |
US61/327,543 | 2010-04-23 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2011133719A2 WO2011133719A2 (en) | 2011-10-27 |
WO2011133719A3 true WO2011133719A3 (en) | 2012-04-05 |
Family
ID=44834795
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2011/033322 WO2011133719A2 (en) | 2010-04-23 | 2011-04-20 | Anti-viral compounds |
Country Status (2)
Country | Link |
---|---|
TW (1) | TW201202231A (en) |
WO (1) | WO2011133719A2 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JOP20180092A1 (en) | 2017-10-13 | 2019-04-13 | Gilead Sciences Inc | Hiv protease inhibitors |
TW202104210A (en) | 2019-04-17 | 2021-02-01 | 美商基利科學股份有限公司 | Hiv protease inhibitors |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005020990A1 (en) * | 2003-07-30 | 2005-03-10 | Centre National De La Recherche Scientifique | Antibiotic thiazolidines |
US7566732B2 (en) * | 2003-10-28 | 2009-07-28 | Rigel Pharmaceuticals, Inc. | Rhodanine compositions for use as antiviral agents |
-
2011
- 2011-04-20 WO PCT/US2011/033322 patent/WO2011133719A2/en active Application Filing
- 2011-04-22 TW TW100114199A patent/TW201202231A/en unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005020990A1 (en) * | 2003-07-30 | 2005-03-10 | Centre National De La Recherche Scientifique | Antibiotic thiazolidines |
US7566732B2 (en) * | 2003-10-28 | 2009-07-28 | Rigel Pharmaceuticals, Inc. | Rhodanine compositions for use as antiviral agents |
Also Published As
Publication number | Publication date |
---|---|
TW201202231A (en) | 2012-01-16 |
WO2011133719A2 (en) | 2011-10-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2011133722A3 (en) | Anti-viral compounds | |
WO2013049352A3 (en) | Anti-viral compounds | |
WO2011133729A3 (en) | Anti-viral compounds | |
WO2011133728A3 (en) | Anti-viral compounds | |
WO2011133727A3 (en) | Anti-viral compounds | |
WO2012166425A3 (en) | Methods of amplifying whole genome of a single cell | |
WO2011056650A9 (en) | Methods and compositions for treating and preventing viral infections | |
WO2012048099A3 (en) | Nanoparticle-loaded cells | |
WO2014052836A3 (en) | Methods and compositions for treating infection | |
WO2013049407A3 (en) | Anti-viral compounds | |
WO2013119916A3 (en) | Compounds for treating spinal muscular atrophy | |
WO2013075083A8 (en) | Modulators of methyl modifying enzymes, compositions and uses thereof | |
WO2013120104A3 (en) | Modulators of methyl modifying enzymes, compositions and uses thereof | |
WO2013075084A8 (en) | Modulators of methyl modifying enzymes, compositions and uses thereof | |
WO2013026740A3 (en) | Methods and means to modify a plant genome | |
WO2012068589A3 (en) | Modulators of methyl modifying enzymes, compositions and uses thereof | |
WO2012083048A3 (en) | Anti-viral compounds | |
MY181898A (en) | Heterocyclic compounds and uses thereof | |
WO2012083053A3 (en) | Anti-viral compounds | |
WO2011113060A3 (en) | Antiviral compounds and methods of use thereof | |
EP2527404A4 (en) | Composition for ultraviolet ray-absorbable member, and ultraviolet ray-absorbable member comprising same | |
WO2012083061A3 (en) | Anti-viral compounds | |
WO2011160024A3 (en) | Compounds useful as antiviral agents, compositions, and methods of use | |
WO2012103810A1 (en) | Certain chemical entities, compositions, and methods | |
WO2013130963A8 (en) | Compositions and methods for treating type iii gaucher disease |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 11772672 Country of ref document: EP Kind code of ref document: A2 |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
122 | Ep: pct application non-entry in european phase |
Ref document number: 11772672 Country of ref document: EP Kind code of ref document: A2 |