WO2000009984A2 - Structure of brush for examining uterine cervical cancer - Google Patents

Structure of brush for examining uterine cervical cancer Download PDF

Info

Publication number
WO2000009984A2
WO2000009984A2 PCT/KR1999/000433 KR9900433W WO0009984A2 WO 2000009984 A2 WO2000009984 A2 WO 2000009984A2 KR 9900433 W KR9900433 W KR 9900433W WO 0009984 A2 WO0009984 A2 WO 0009984A2
Authority
WO
WIPO (PCT)
Prior art keywords
brush
cervical cancer
uterine cervical
examination method
brush part
Prior art date
Application number
PCT/KR1999/000433
Other languages
French (fr)
Other versions
WO2000009984A3 (en
Inventor
Hyuk Jung
Original Assignee
Hyuk Jung
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hyuk Jung filed Critical Hyuk Jung
Priority to AU50699/99A priority Critical patent/AU5069999A/en
Publication of WO2000009984A2 publication Critical patent/WO2000009984A2/en
Publication of WO2000009984A3 publication Critical patent/WO2000009984A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0291Instruments for taking cell samples or for biopsy for uterus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/43Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4318Evaluation of the lower reproductive system
    • A61B5/4331Evaluation of the lower reproductive system of the cervix
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6867Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
    • A61B5/6875Uterus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B2010/0216Sampling brushes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B2010/0225Instruments for taking cell samples or for biopsy for taking multiple samples
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B2017/320004Surgical cutting instruments abrasive
    • A61B2017/320012Brushes

Definitions

  • the present invention relates to a structure of an uterine cervical cancer examining
  • Uterine cervical cancer is one of the most prevailing women's diseases that reflect
  • An effective means for reducing uterine cervical cancer is a selective examination
  • the uterine cervical cell examination method which is developed by Papanicolaou in
  • the uterine cervix is divided into two parts, endocervix and exocervix.
  • uterine cervical cancer primarily occurs at a joining region between the endocervix and the
  • an I-shaped brush 100 includes a 5mm-diameter brush part 1 formed around a 2cm-
  • shaped brush 100 is however designed to be used for endocervix 7 only and often fails to
  • an object of the present invention is to provide a brush structure for use
  • the brush further includes: a 1.2cm-length screw wire 3 being provided with the 5mm-diameter brush part 1 formed
  • FIG. 1 is a perspective view of a related art I-shaped brush
  • FIG. 2 is a vertical sectional view of the related art I-shaped brush
  • FIG. 3 shows a medical examination method for an endocervix with the related art I-
  • FIG. 4 shows a pathic cell collected with the related art I-shaped brush and transferred
  • FIG. 5 is a perspective view of (i) an L-shaped brush and (ii) a T-shaped brush
  • FIG. 6(i) shows a medical examination method for both an endocervix and an
  • FIG. 6(ii) shows a medical examination method for both the endocervix and the
  • FIG. 7 shows pathic cells on a slide, extracted from the exocervix on the left side and
  • FIG. 5 is a perspective view of a brush for use in the medical examination method of
  • the brush has a side brush part 1 ' formed on either side or
  • FIG. 6(i) shows a medical examination method for both an
  • FIG. 6(ii) shows a medical examination method for both the endocervix and the exocervix
  • the brush is taken to pathic cells at the endocervix 7 and the
  • exocervix 6 that protrudes from the endocervix 7, with a gripe 2 being turned clockwise or
  • exocervix 6 The pathic cells taken from the exocervix 6 are placed on the left side of a slide 400
  • shaped brush can be manufactured at a low cost into a simple structure that the 5mm-diameter
  • side brush part 1' is formed integrally with the brush part 1 on either side or both sides of the

Abstract

Provided with a brush (300) for use in an examination method of uterine cervical cancer which has a brush part (1) formed on a 15 cm-length and 2.5 mm-diameter soft plastic grip (2), the brush (300) including: a 1.2 cm-length screw wire being provided with the 5 mm-diameter brush part (1) formed thereon, wherein the screw wire with the brush part (1) is inserted lengthwise in the grip (2); and a 5 mm-diameter side brush part (1') being formed integrally with the brush part (1) on either side or both sides of the 2 cm-length screw wire.

Description

STRUCTURE OFBRUSH FOREXAMINING UTERINE CERVICAL CANCER
BACKGROUND OF THE INVENTION
Field of the Invention
The present invention relates to a structure of an uterine cervical cancer examining
brush.
Background of the Related Art
Uterine cervical cancer is one of the most prevailing women's diseases that reflect
underdevelopment of a nation and incur a serious loss to women in social and economical
aspects. An effective means for reducing uterine cervical cancer is a selective examination
method. For several scores of years, the uterine cervical cell examination method has been
considered as a most effective and economical selective examination method.
The uterine cervical cell examination method, which is developed by Papanicolaou in
1928, has been employed as a mass examination method on a government scale in every
countries of North America and Europe. Due to the selective examination method performed
for the past scores of years, the occurrence rate of uterine cervical cancer has been
dramatically reduced as well as a decrease in the death rate caused by that disease (See.,
Kosa, 1989; Richart, 1959; Burns et al, 1969). It is however is reported that approximately 6,000 women a year newly suffer from
the uterine cervical cancer in Korea where the selective examination method has been
performed for scores of years, which fact suggests that the selective examination method for
the uterine cervical cancer leaves much to be improved (Ref. the Ministry of Health &
society, 1993).
Particularly, it is also reported that women who suffer from the uterine cervical cancer
are still found out even in the British Columbia of Canada where the mass examination
method rate for the uterine cervical cancer reaches 100 percents. According to the report, it
results from a high false-negative rate for the uterine cervical cancer in the uterine cervical
cell examination method, which comes up to 6-55% (See. Soost et all.. 1991; Sherman et al.,
1994; Orr & Shingleton et al., 1995; Coppelson & Brown, 1974; Fetherson, 1983; and Maggi
et al., 1989).
Such a high incorrect diagnosis rate of the selective examination method for the
uterine cervical cancer is considered to be caused by a disadvantageous method of collecting
a test sample from a cervix. So many models have been developed to overcome the above
problem but there still exists no effective solution for the problem yet.
The uterine cervix is divided into two parts, endocervix and exocervix. Although the
uterine cervical cancer primarily occurs at a joining region between the endocervix and the
exocervix, the related art tools for an examination method of the uterine cervical cancer are
designed to separately examine the endocervix and the exocervix. This troublesome processes for examining the two parts of the cervix separately cause incorrect diagnoses.
There are several types of tools used to collect pathic cells from a cervix in the
medical examination method of the uterine cervical cancer. But, the related art tools leave
much to be desired to collect pathic cells from the entire part of the cervix. For example, an
I-shaped brush patented by Medscan Co. in Sweden is widely used. As illustrated in FIGs. 1
to 4, an I-shaped brush 100 includes a 5mm-diameter brush part 1 formed around a 2cm-
length screw wire 3 with a 15cm-length and 2.5mm-diameter soft plastic gripe 2. The I-
shaped brush 100 is however designed to be used for endocervix 7 only and often fails to
collect pathic cells of exocervix 6 where the uterine cervical cancer occurs most than other
regions of the cervix. This causes a high incorrect diagnosis rate.
SUMMARY OF THE INVENTION
Accordingly, an object of the present invention is to provide a brush structure for use
in the medical examination method for the uterine cervical cancer, designed to collect pathic
cells from both endocervix and exocervix by a single operation, thereby making it possible to
have an accurate acknowledge of the location of the cancer as well as improving incorrect
diagnosis rate of the related art I-shaped brushes.
To achieve the above object of the present invention, there is provided a brush for use
in an examination method of the uterine cervical cancer which includes a brush part 1 formed
on a 15cm-length and 2.5mm-diameter soft plastic gripe 2. The brush further includes: a 1.2cm-length screw wire 3 being provided with the 5mm-diameter brush part 1 formed
thereon, wherein the screw wire 3 with the brush part 1 is inserted lengthwise in the gripe 2;
and a 5mm-diameter side brush part 1' being formed integrally with the brush part 1 on either
side or both sides of the 2cm-length screw wire 2.
BRIEF DESCRIPTION OF THE DRAWINGS
The accompanying drawings, which are included to provide a further understanding of
the invention and are incorporated in and constitute a part of this specification, illustrate
embodiments of the invention and together with the description serve to explain the principles
of the drawings:
In the drawings:
FIG. 1 is a perspective view of a related art I-shaped brush;
FIG. 2 is a vertical sectional view of the related art I-shaped brush;
FIG. 3 shows a medical examination method for an endocervix with the related art I-
shaped brush;
FIG. 4 shows a pathic cell collected with the related art I-shaped brush and transferred
on a slide;
FIG. 5 is a perspective view of (i) an L-shaped brush and (ii) a T-shaped brush
according to the present invention;
FIG. 6(i) shows a medical examination method for both an endocervix and an
exocervix with the L-shaped brush shown in FIG. 5; FIG. 6(ii) shows a medical examination method for both the endocervix and the
exocervix with the T-shaped brush shown in FIG. 5; and
FIG. 7 shows pathic cells on a slide, extracted from the exocervix on the left side and
from the endocervix on the right side, wherein (i) pathic cells are collected with the L-shaped
brush and (ii) pathic cells with the T-shaped brush.
DETAILED DESCRIPTION OF PREFERRED EMBODIMENT
Hereinafter, the present invention will be described in detail with reference to the
accompanying drawings.
FIG. 5 is a perspective view of a brush for use in the medical examination method of
uterine cervical cancer, wherein the brush has a side brush part 1 ' formed on either side or
both sides of the brush. FIG. 6(i) shows a medical examination method for both an
endocervix and an exocervix with an L-shaped brush according to the present invention, and
FIG. 6(ii) shows a medical examination method for both the endocervix and the exocervix
with a T-shaped brush according to the present invention.
Referring to FIG. 6, the brush is taken to pathic cells at the endocervix 7 and the
exocervix 6 that protrudes from the endocervix 7, with a gripe 2 being turned clockwise or
counter clockwise.
Now, reference will be made to the effects of the present invention L-shaped or T-
shaped brush that is useful to collect pathic cells from both the endocervix 7 and the
exocervix 6. The pathic cells taken from the exocervix 6 are placed on the left side of a slide 400
with the pathic cells from the endocervix 7 being on the right side of the slide 400. This
makes it possible to examine the pathic cells of the exocervix 6 separately from the pathic
cells of the endocervix 7,
Compared with the related art I-shaped brush, the present invention L-shaped or T-
shaped brush can be manufactured at a low cost into a simple structure that the 5mm-diameter
side brush part 1' is formed integrally with the brush part 1 on either side or both sides of the
2cm-length screw wire 3, wherein the screw wire 3 with the brush parts 1 and 1' is inserted in
the gripe 2. This brush structure is expected to be widely used in all parts of the world and
greatly contribute to a reduction of the uterine cervical cancer rate.
It can be known from this inventor's experience with the novel brush at a university
hospital that the present invention is very useful to exactly collect pathic cells from both the
endocervix and the exocervix and improve high erroneous diagnosis rate with the related art
brush.
It will be apparent to those skilled in the art that various modifications and variations
can be made in the present invention without departing from the spirit or scope of the
invention. Thus, it is intended that the present invention cover the modifications and
variations of this invention provided they come within the scope of the appended claims and
their equivalents.

Claims

What is claimed is:
1. A brush for use in an examination method of uterine cervical cancer which
includes a brush part formed on a 15cm-length and 2.5mm-diameter soft plastic gripe, the
brush comprising:
a 1.2cm-length screw wire being provided with the 5mm-diameter brush part formed
thereon, wherein the screw wire with the brush part is inserted lengthwise in the gripe; and
a 5mm-diameter side brush part being formed integrally with the brush part on either
side or both sides of the 2cm-length screw wire.
PCT/KR1999/000433 1998-08-17 1999-08-05 Structure of brush for examining uterine cervical cancer WO2000009984A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU50699/99A AU5069999A (en) 1998-08-17 1999-08-05 Structure of brush for examining uterine cervical cancer

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1019980033549A KR19980082053A (en) 1998-08-17 1998-08-17 Structure of cervical cancer screening brush
KR1998/33549 1998-08-17

Publications (2)

Publication Number Publication Date
WO2000009984A2 true WO2000009984A2 (en) 2000-02-24
WO2000009984A3 WO2000009984A3 (en) 2000-06-22

Family

ID=19547598

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR1999/000433 WO2000009984A2 (en) 1998-08-17 1999-08-05 Structure of brush for examining uterine cervical cancer

Country Status (3)

Country Link
KR (1) KR19980082053A (en)
AU (1) AU5069999A (en)
WO (1) WO2000009984A2 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120150088A1 (en) * 2003-04-01 2012-06-14 Daniele Triva Swab for Collecting Biological Specimens
US8631715B2 (en) 2010-06-09 2014-01-21 Copan Italia S.P.A. Method for quantitative transfer of analytes
US9170177B2 (en) 2012-09-25 2015-10-27 Copan Italia S.P.A. Device and a method for collecting and transferring samples of biological material
US10092275B2 (en) 2011-01-05 2018-10-09 Copan Italia S.P.A. Process for realising a device for collecting and transferring samples for molecular biology
US10182796B2 (en) 2012-11-30 2019-01-22 Eve Medical Inc. Specimen collection device and kit

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4108162A (en) * 1975-12-28 1978-08-22 Kiyoshi Chikashige Twisted wire brush with threaded assembly for collecting cells
US4227537A (en) * 1978-03-08 1980-10-14 Tucson Medical Instruments, Inc. Endometrial brush with slidable protective sleeve
US4759376A (en) * 1984-05-29 1988-07-26 Nils Stormby Endocervical sampling brush and smear method
GB2208603A (en) * 1987-07-03 1989-04-12 Richards Dr Peter William Cervical sampling device
DE4005266A1 (en) * 1990-02-20 1991-08-22 Geka Brush Georg Karl Gmbh Scraper head for collecting cytological smears - has foamed polymer elements forming bristles or bladed surface
EP0763345A1 (en) * 1995-09-13 1997-03-19 VANCE PRODUCTS INCORPORATED d/b/a COOK UROLOGICAL INCORPORATED Uterine endometrial tissue sample brush

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4108162A (en) * 1975-12-28 1978-08-22 Kiyoshi Chikashige Twisted wire brush with threaded assembly for collecting cells
US4227537A (en) * 1978-03-08 1980-10-14 Tucson Medical Instruments, Inc. Endometrial brush with slidable protective sleeve
US4759376A (en) * 1984-05-29 1988-07-26 Nils Stormby Endocervical sampling brush and smear method
GB2208603A (en) * 1987-07-03 1989-04-12 Richards Dr Peter William Cervical sampling device
DE4005266A1 (en) * 1990-02-20 1991-08-22 Geka Brush Georg Karl Gmbh Scraper head for collecting cytological smears - has foamed polymer elements forming bristles or bladed surface
EP0763345A1 (en) * 1995-09-13 1997-03-19 VANCE PRODUCTS INCORPORATED d/b/a COOK UROLOGICAL INCORPORATED Uterine endometrial tissue sample brush

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120150088A1 (en) * 2003-04-01 2012-06-14 Daniele Triva Swab for Collecting Biological Specimens
US8979784B2 (en) * 2003-04-01 2015-03-17 Copan Italia S.P.A. Swab for collecting biological specimens
US10327741B2 (en) 2003-04-01 2019-06-25 Copan Italia S.P.A. Swab for collecting biological specimens
US11364018B2 (en) 2003-04-01 2022-06-21 Copan Italia S.P.A. Swab for collecting biological specimens
US11446012B2 (en) 2003-04-01 2022-09-20 Copan Italia S.P.A. Swab for collecting biological specimens
US8631715B2 (en) 2010-06-09 2014-01-21 Copan Italia S.P.A. Method for quantitative transfer of analytes
US10092275B2 (en) 2011-01-05 2018-10-09 Copan Italia S.P.A. Process for realising a device for collecting and transferring samples for molecular biology
US9170177B2 (en) 2012-09-25 2015-10-27 Copan Italia S.P.A. Device and a method for collecting and transferring samples of biological material
US10182796B2 (en) 2012-11-30 2019-01-22 Eve Medical Inc. Specimen collection device and kit

Also Published As

Publication number Publication date
WO2000009984A3 (en) 2000-06-22
AU5069999A (en) 2000-03-06
KR19980082053A (en) 1998-11-25

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