DE602005024418D1 - Elektrobenetzende abgabevorrichtungen und dazugehörige verfahren - Google Patents

Elektrobenetzende abgabevorrichtungen und dazugehörige verfahren

Info

Publication number
DE602005024418D1
DE602005024418D1 DE602005024418T DE602005024418T DE602005024418D1 DE 602005024418 D1 DE602005024418 D1 DE 602005024418D1 DE 602005024418 T DE602005024418 T DE 602005024418T DE 602005024418 T DE602005024418 T DE 602005024418T DE 602005024418 D1 DE602005024418 D1 DE 602005024418D1
Authority
DE
Germany
Prior art keywords
electroconducting
dispensers
liquid
methods therefor
dispensing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005024418T
Other languages
English (en)
Inventor
Charles S Vann
Debjyoti Banerjee
Timothy G Geiser
James C Nurse
Nigel P Beard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Life Technologies Corp
Original Assignee
Life Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Technologies Corp filed Critical Life Technologies Corp
Publication of DE602005024418D1 publication Critical patent/DE602005024418D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44743—Introducing samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J4/00—Feed or outlet devices; Feed or outlet control devices
    • B01J4/008—Feed or outlet control devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B01L3/0268—Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • B01L3/502792—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics for moving individual droplets on a plate, e.g. by locally altering surface tension
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
    • B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315—Microtiter plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/0036—Nozzles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00418—Means for dispensing and evacuation of reagents using pressure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00653—Making arrays on substantially continuous surfaces the compounds being bound to electrodes embedded in or on the solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/089—Virtual walls for guiding liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/02—Drop detachment mechanisms of single droplets from nozzles or pins
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0427—Electrowetting
DE602005024418T 2004-08-26 2005-08-26 Elektrobenetzende abgabevorrichtungen und dazugehörige verfahren Active DE602005024418D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60484504P 2004-08-26 2004-08-26
PCT/US2005/030247 WO2006026351A1 (en) 2004-08-26 2005-08-26 Electrowetting dispensing devices and related methods

Publications (1)

Publication Number Publication Date
DE602005024418D1 true DE602005024418D1 (de) 2010-12-09

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005024418T Active DE602005024418D1 (de) 2004-08-26 2005-08-26 Elektrobenetzende abgabevorrichtungen und dazugehörige verfahren

Country Status (5)

Country Link
US (11) US20060102477A1 (de)
EP (1) EP1789195B1 (de)
AT (1) ATE485888T1 (de)
DE (1) DE602005024418D1 (de)
WO (1) WO2006026351A1 (de)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6911132B2 (en) 2002-09-24 2005-06-28 Duke University Apparatus for manipulating droplets by electrowetting-based techniques
US7329545B2 (en) 2002-09-24 2008-02-12 Duke University Methods for sampling a liquid flow
WO2006026351A1 (en) 2004-08-26 2006-03-09 Applera Corporation Electrowetting dispensing devices and related methods
EP1859330B1 (de) 2005-01-28 2012-07-04 Duke University Vorrichtungen und verfahren zur manipulation von tropfen auf einer leiterplatte
FR2887030B1 (fr) * 2005-06-09 2008-06-13 Commissariat Energie Atomique Dispositif planaire avec adressage de puits automatise par electromouillage dynamique
EP2660482B1 (de) 2005-08-22 2019-08-07 Life Technologies Corporation Vorrichtung, System und Verfahren unter Verwendung von nichtmischbaren Flüssigkeiten mit unterschiedlichen Volumen
US9476856B2 (en) 2006-04-13 2016-10-25 Advanced Liquid Logic, Inc. Droplet-based affinity assays
US8637317B2 (en) 2006-04-18 2014-01-28 Advanced Liquid Logic, Inc. Method of washing beads
US20140193807A1 (en) 2006-04-18 2014-07-10 Advanced Liquid Logic, Inc. Bead manipulation techniques
US8613889B2 (en) 2006-04-13 2013-12-24 Advanced Liquid Logic, Inc. Droplet-based washing
US8492168B2 (en) 2006-04-18 2013-07-23 Advanced Liquid Logic Inc. Droplet-based affinity assays
WO2007123908A2 (en) 2006-04-18 2007-11-01 Advanced Liquid Logic, Inc. Droplet-based multiwell operations
US8980198B2 (en) 2006-04-18 2015-03-17 Advanced Liquid Logic, Inc. Filler fluids for droplet operations
US8658111B2 (en) 2006-04-18 2014-02-25 Advanced Liquid Logic, Inc. Droplet actuators, modified fluids and methods
US7901947B2 (en) 2006-04-18 2011-03-08 Advanced Liquid Logic, Inc. Droplet-based particle sorting
US7851184B2 (en) 2006-04-18 2010-12-14 Advanced Liquid Logic, Inc. Droplet-based nucleic acid amplification method and apparatus
US7763471B2 (en) 2006-04-18 2010-07-27 Advanced Liquid Logic, Inc. Method of electrowetting droplet operations for protein crystallization
US7439014B2 (en) 2006-04-18 2008-10-21 Advanced Liquid Logic, Inc. Droplet-based surface modification and washing
US8809068B2 (en) 2006-04-18 2014-08-19 Advanced Liquid Logic, Inc. Manipulation of beads in droplets and methods for manipulating droplets
US8716015B2 (en) 2006-04-18 2014-05-06 Advanced Liquid Logic, Inc. Manipulation of cells on a droplet actuator
US7815871B2 (en) 2006-04-18 2010-10-19 Advanced Liquid Logic, Inc. Droplet microactuator system
US7816121B2 (en) 2006-04-18 2010-10-19 Advanced Liquid Logic, Inc. Droplet actuation system and method
US8637324B2 (en) 2006-04-18 2014-01-28 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
US8470606B2 (en) 2006-04-18 2013-06-25 Duke University Manipulation of beads in droplets and methods for splitting droplets
US10078078B2 (en) 2006-04-18 2018-09-18 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
US8041463B2 (en) 2006-05-09 2011-10-18 Advanced Liquid Logic, Inc. Modular droplet actuator drive
WO2009111769A2 (en) 2008-03-07 2009-09-11 Advanced Liquid Logic, Inc. Reagent and sample preparation and loading on a fluidic device
US7939021B2 (en) 2007-05-09 2011-05-10 Advanced Liquid Logic, Inc. Droplet actuator analyzer with cartridge
US7822510B2 (en) 2006-05-09 2010-10-26 Advanced Liquid Logic, Inc. Systems, methods, and products for graphically illustrating and controlling a droplet actuator
JP5103614B2 (ja) * 2006-11-27 2012-12-19 国立大学法人九州工業大学 微量液体分取デバイス
US20100024908A1 (en) * 2006-11-27 2010-02-04 Takashi Yasuda Microvolume liquid dispensing device
WO2008091848A2 (en) * 2007-01-22 2008-07-31 Advanced Liquid Logic, Inc. Surface assisted fluid loading and droplet dispensing
EP2573562A3 (de) 2007-02-09 2013-10-30 Advanced Liquid Logic, Inc. Tröpfchenaktuatorvorrichtungen und Verfahren zur Manipulation von Kügelchen
US20100025250A1 (en) * 2007-03-01 2010-02-04 Advanced Liquid Logic, Inc. Droplet Actuator Structures
WO2011084703A2 (en) 2009-12-21 2011-07-14 Advanced Liquid Logic, Inc. Enzyme assays on a droplet actuator
DE102007018056A1 (de) * 2007-04-17 2008-10-23 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren und Vorrichtung zur Tropfenmanipulation
WO2009021233A2 (en) 2007-08-09 2009-02-12 Advanced Liquid Logic, Inc. Pcb droplet actuator fabrication
US8702938B2 (en) 2007-09-04 2014-04-22 Advanced Liquid Logic, Inc. Droplet actuator with improved top substrate
DE102007047415B3 (de) * 2007-10-04 2009-04-02 Dräger Medical AG & Co. KG Flüssigkeitsverdampfer
CN101945767B (zh) 2007-12-23 2013-10-30 先进液体逻辑公司 液滴致动器配置以及引导液滴操作的方法
WO2009111431A2 (en) 2008-03-04 2009-09-11 Waters Technologies Corporation Interfacing with a digital microfluidic device
WO2009137415A2 (en) 2008-05-03 2009-11-12 Advanced Liquid Logic, Inc. Reagent and sample preparation, loading, and storage
WO2010019782A2 (en) * 2008-08-13 2010-02-18 Advanced Liquid Logic, Inc. Methods, systems, and products for conducting droplet operations
FR2937690B1 (fr) * 2008-10-28 2010-12-31 Commissariat Energie Atomique Micropome a actionnement par gouttes
US8877512B2 (en) * 2009-01-23 2014-11-04 Advanced Liquid Logic, Inc. Bubble formation techniques using physical or chemical features to retain a gas bubble within a droplet actuator
US8628648B2 (en) * 2009-07-07 2014-01-14 The University Of Akron Apparatus and method for manipulating micro component
US8926065B2 (en) 2009-08-14 2015-01-06 Advanced Liquid Logic, Inc. Droplet actuator devices and methods
WO2011057197A2 (en) 2009-11-06 2011-05-12 Advanced Liquid Logic, Inc. Integrated droplet actuator for gel electrophoresis and molecular analysis
US9182591B2 (en) 2009-12-16 2015-11-10 University Of South Florida System and method for electrowetting actuation utilizing diodes
TW201122545A (en) * 2009-12-31 2011-07-01 Wintek Corp Electrowetting display and pixel array substrate thereof and electrowetting display pixel structure thereof
WO2011135044A1 (en) * 2010-04-29 2011-11-03 Samsung Lcd Netherlands R & D Center B.V. Improvements in relation to a manufacturing method for an electrowetting device
US8602532B2 (en) * 2011-04-30 2013-12-10 Hewlett-Packard Development Company, L.P. Electrowetting mechanism for fluid-application device
WO2012154745A2 (en) 2011-05-09 2012-11-15 Advanced Liquid Logic, Inc. Microfluidic feedback using impedance detection
AR087158A1 (es) 2011-06-20 2014-02-26 Gen Biscuit Masita en capas saludable
BR112014000257A2 (pt) 2011-07-06 2017-03-01 Advanced Liquid Logic Inc armazenamento de reagente em um atuador de gota
WO2013009927A2 (en) 2011-07-11 2013-01-17 Advanced Liquid Logic, Inc. Droplet actuators and techniques for droplet-based assays
US9446404B2 (en) 2011-07-25 2016-09-20 Advanced Liquid Logic, Inc. Droplet actuator apparatus and system
US10731199B2 (en) 2011-11-21 2020-08-04 Advanced Liquid Logic, Inc. Glucose-6-phosphate dehydrogenase assays
WO2014004908A1 (en) 2012-06-27 2014-01-03 Advanced Liquid Logic Inc. Techniques and droplet actuator designs for reducing bubble formation
WO2014014892A2 (en) * 2012-07-16 2014-01-23 Cornell University System and methods for electrowetting based pick and place assembly
KR20140065271A (ko) * 2012-11-21 2014-05-29 삼성디스플레이 주식회사 액정 표시 장치 및 그 제조 방법
ITTO20130264A1 (it) * 2013-03-29 2014-09-30 St Microelectronics Srl Microreattore e metodo per caricare un liquido nel microreattore
WO2015170268A1 (en) 2014-05-09 2015-11-12 Dh Technologies Development Pte. Ltd. Fluid transfer from digital microfluidic device
WO2016130962A1 (en) 2015-02-13 2016-08-18 Abbott Laboratories Automated storage modules for diagnostic analyzer liquids and related systems and methods
EP3311919B1 (de) * 2016-10-19 2021-04-14 Sharp Life Science (EU) Limited Extraktion von flüssigkeit aus einer mikrofluidischen vorrichtung
US10989181B1 (en) * 2017-11-14 2021-04-27 Verily Life Sciences Llc Electrowetting-based pump
EP3704493A4 (de) * 2018-01-26 2020-11-18 Hewlett-Packard Development Company, L.P. Spenderplattformen
EP3837344A4 (de) * 2018-08-17 2022-01-26 Sierra Biosystems, Inc. Zeilenunabhängige oligonukleotidsynthese
DE112018007861T5 (de) * 2018-10-17 2021-04-22 Hitachi High-Tech Corporation Biochemische Kassette und biochemische Analysevorrichtung
US11474007B2 (en) 2019-01-04 2022-10-18 Funai Electric Co., Ltd. Digital dispense system
US11768215B2 (en) * 2019-01-04 2023-09-26 Funai Electric Co., Ltd. Digital dispense system cartridge
WO2020242477A1 (en) * 2019-05-30 2020-12-03 Massachusetts Institute Of Technology Propulsion systems including electrically actuated valve
US20220362772A1 (en) * 2019-07-03 2022-11-17 The Johns Hopkins University Immobilization and quantitative measurement of droplets
DE102019216886A1 (de) * 2019-10-31 2021-05-06 Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. Transfer zumindest eines partikels in einer flüssigkeit von einer abgabeeinheit zu einer empfangseinheit
US11927740B2 (en) 2019-11-20 2024-03-12 Nuclera Ltd Spatially variable hydrophobic layers for digital microfluidics
US11554374B2 (en) 2020-01-17 2023-01-17 Nuclera Nucleics Ltd. Spatially variable dielectric layers for digital microfluidics
US11946901B2 (en) 2020-01-27 2024-04-02 Nuclera Ltd Method for degassing liquid droplets by electrical actuation at higher temperatures
JP2023513832A (ja) 2020-02-18 2023-04-03 ヌークレラ ヌクリークス， リミテッド Ｅｗｏｄアレイの高周波ａｃ駆動のためのアダプティブゲート駆動
EP4106920A4 (de) 2020-02-19 2024-03-20 Nuclera Ltd Verrasteter transistorantrieb für hochfrequenz-wechselstromansteuerung von ewod-anordnungen
CN115461152A (zh) 2020-04-27 2022-12-09 核酸有限公司 用于数字微流体的可变驱动和短路保护的分段顶板
WO2021242265A1 (en) * 2020-05-29 2021-12-02 Hewlett-Packard Development Company, L.P. Controlling microfluidic movement via airborne charges
GB2597958A (en) * 2020-08-11 2022-02-16 Univ Of Hertfordshire Higher Education Corporation Droplet generation system
CN114336510A (zh) * 2020-09-30 2022-04-12 富佳生技股份有限公司 介电润湿装置及其电路检测方法
US11645156B1 (en) 2021-10-29 2023-05-09 Hewlett Packard Enterprise Development Lp Updating error policy
DE102022201938A1 (de) 2022-02-24 2023-08-24 Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. Flüssigkeitstransfer zwischen rotierenden Modulen
GB2621844A (en) * 2022-08-23 2024-02-28 Lightcast Discovery Ltd Improvements in or relating to a composite wall of a device

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4677058A (en) * 1983-05-19 1987-06-30 Karl Tryggvason Detecting malignant cells with monoclonal antibodies specific to type IV collagenase enzyme
US5480735A (en) * 1990-06-25 1996-01-02 International Fuel Cells Corporation High current alkaline fuel cell electrodes
US5610287A (en) * 1993-12-06 1997-03-11 Molecular Tool, Inc. Method for immobilizing nucleic acid molecules
US5741462A (en) * 1995-04-25 1998-04-21 Irori Remotely programmable matrices with memories
US6379929B1 (en) * 1996-11-20 2002-04-30 The Regents Of The University Of Michigan Chip-based isothermal amplification devices and methods
WO1998049344A1 (en) * 1997-04-28 1998-11-05 Lockheed Martin Energy Research Corporation Method and apparatus for analyzing nucleic acids
US5980719A (en) * 1997-05-13 1999-11-09 Sarnoff Corporation Electrohydrodynamic receptor
US6106685A (en) * 1997-05-13 2000-08-22 Sarnoff Corporation Electrode combinations for pumping fluids
US6042879A (en) 1997-07-02 2000-03-28 United Technologies Corporation Method for preparing an apertured article to be recoated
US6375871B1 (en) * 1998-06-18 2002-04-23 3M Innovative Properties Company Methods of manufacturing microfluidic articles
WO1999014368A2 (en) * 1997-09-15 1999-03-25 Whitehead Institute For Biomedical Research Methods and apparatus for processing a sample of biomolecular analyte using a microfabricated device
AU744879B2 (en) * 1997-09-19 2002-03-07 Aclara Biosciences, Inc. Apparatus and method for transferring liquids
US6565727B1 (en) * 1999-01-25 2003-05-20 Nanolytics, Inc. Actuators for microfluidics without moving parts
IT1309430B1 (it) * 1999-05-18 2002-01-23 Guerrieri Roberto Metodo ed apparato per la manipolazione di particelle per mezzo delladielettroforesi
WO2002007503A1 (en) * 2000-07-25 2002-01-31 The Regents Of The University Of California Electrowetting-driven micropumping
US7192559B2 (en) * 2000-08-03 2007-03-20 Caliper Life Sciences, Inc. Methods and devices for high throughput fluid delivery
US6773566B2 (en) * 2000-08-31 2004-08-10 Nanolytics, Inc. Electrostatic actuators for microfluidics and methods for using same
WO2002023163A1 (en) * 2000-09-15 2002-03-21 California Institute Of Technology Microfabricated crossflow devices and methods
JP4184078B2 (ja) * 2000-11-09 2008-11-19 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ マトリックスアドレッシングの手段により制御可能な流動体レベルを伴う多重の流動体要素
US6918309B2 (en) * 2001-01-17 2005-07-19 Irm Llc Sample deposition method and system
KR100398309B1 (ko) * 2001-02-20 2003-09-19 한국과학기술원 연속 전기습윤에 의해 유도된 운동하는 액체 방울에 의해구동되는 마이크로펌프
CA2438955C (en) * 2001-02-23 2008-12-09 Japan Science And Technology Corporation Method and device for handling liquid particulates
US6949176B2 (en) * 2001-02-28 2005-09-27 Lightwave Microsystems Corporation Microfluidic control using dielectric pumping
US7016560B2 (en) * 2001-02-28 2006-03-21 Lightwave Microsystems Corporation Microfluidic control for waveguide optical switches, variable attenuators, and other optical devices
US6538823B2 (en) * 2001-06-19 2003-03-25 Lucent Technologies Inc. Tunable liquid microlens
US6965480B2 (en) * 2001-06-19 2005-11-15 Lucent Technologies Inc. Method and apparatus for calibrating a tunable microlens
US6665127B2 (en) * 2002-04-30 2003-12-16 Lucent Technologies Inc. Method and apparatus for aligning a photo-tunable microlens
US7014747B2 (en) * 2001-06-20 2006-03-21 Sandia Corporation Dielectrophoretic systems without embedded electrodes
US6545815B2 (en) * 2001-09-13 2003-04-08 Lucent Technologies Inc. Tunable liquid microlens with lubrication assisted electrowetting
US7094379B2 (en) * 2001-10-24 2006-08-22 Commissariat A L'energie Atomique Device for parallel and synchronous injection for sequential injection of different reagents
US20040231987A1 (en) * 2001-11-26 2004-11-25 Keck Graduate Institute Method, apparatus and article for microfluidic control via electrowetting, for chemical, biochemical and biological assays and the like
EP1450956A2 (de) * 2001-11-26 2004-09-01 Keck Graduate Institute Verfahren und vorrichtung zur mikrofluidischen kontrolle durch elektrowetting für chemische, biochemische und biologische proben
GB0129068D0 (en) * 2001-12-05 2002-01-23 Koninl Philips Electronics Nv Display device
AU2003201481A1 (en) * 2002-02-14 2003-09-04 Koninklijke Philips Electronics N.V. Variable focus lens
US6936196B2 (en) * 2002-03-12 2005-08-30 Lucent Technologies Inc. Solidifiable tunable liquid microlens
US7147763B2 (en) * 2002-04-01 2006-12-12 Palo Alto Research Center Incorporated Apparatus and method for using electrostatic force to cause fluid movement
US6958132B2 (en) * 2002-05-31 2005-10-25 The Regents Of The University Of California Systems and methods for optical actuation of microfluidics based on opto-electrowetting
FR2841063B1 (fr) * 2002-06-18 2004-09-17 Commissariat Energie Atomique Dispositif de deplacement de petits volumes de liquide le long d'un micro-catenaire par des forces electrostatiques
FR2843048B1 (fr) * 2002-08-01 2004-09-24 Commissariat Energie Atomique Dispositif d'injection et de melange de micro-gouttes liquides.
US20040091392A1 (en) * 2002-08-09 2004-05-13 Mcbride Sterling Eduard Method and apparatus for employing a tunable microfluidic device for optical switching, filtering and assaying of biological samples
US6829415B2 (en) * 2002-08-30 2004-12-07 Lucent Technologies Inc. Optical waveguide devices with electro-wetting actuation
CN1330992C (zh) * 2002-09-19 2007-08-08 皇家飞利浦电子股份有限公司 电润湿光学开关
US7329545B2 (en) * 2002-09-24 2008-02-12 Duke University Methods for sampling a liquid flow
US6911132B2 (en) * 2002-09-24 2005-06-28 Duke University Apparatus for manipulating droplets by electrowetting-based techniques
US6989234B2 (en) * 2002-09-24 2006-01-24 Duke University Method and apparatus for non-contact electrostatic actuation of droplets
US7547380B2 (en) * 2003-01-13 2009-06-16 North Carolina State University Droplet transportation devices and methods having a fluid surface
US7299749B2 (en) * 2003-02-10 2007-11-27 Fujifilm Corporation Lithographic printing plate support and production method thereof
US7713485B2 (en) * 2003-03-19 2010-05-11 Industrial Technology Research Institute Microfluidics switch with moving planes
TWI230760B (en) * 2003-07-29 2005-04-11 Univ Tsinghua Electrowetting electrode design with electromagnetic field for actuation of the magnetic-beads biochemical detection system
TWI242466B (en) * 2003-08-29 2005-11-01 Prec Instr Dev Ct Nat Control device and method for controlling liquid droplets
FR2866493B1 (fr) * 2004-02-16 2010-08-20 Commissariat Energie Atomique Dispositif de controle du deplacement d'une goutte entre deux ou plusieurs substrats solides
WO2006026351A1 (en) 2004-08-26 2006-03-09 Applera Corporation Electrowetting dispensing devices and related methods
JP4185904B2 (ja) * 2004-10-27 2008-11-26 株式会社日立ハイテクノロジーズ 液体搬送基板、分析システム、分析方法

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US9671365B2 (en) 2017-06-06
US10215730B2 (en) 2019-02-26
US20150338373A1 (en) 2015-11-26
US20060102477A1 (en) 2006-05-18
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US20140001202A1 (en) 2014-01-02
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US20150008129A1 (en) 2015-01-08
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US20100236930A1 (en) 2010-09-23
ATE485888T1 (de) 2010-11-15

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