CN103315703A - Human eye optical test model for fundus imaging - Google Patents
Human eye optical test model for fundus imaging Download PDFInfo
- Publication number
- CN103315703A CN103315703A CN2013102113349A CN201310211334A CN103315703A CN 103315703 A CN103315703 A CN 103315703A CN 2013102113349 A CN2013102113349 A CN 2013102113349A CN 201310211334 A CN201310211334 A CN 201310211334A CN 103315703 A CN103315703 A CN 103315703A
- Authority
- CN
- China
- Prior art keywords
- test
- lens
- fundus
- external member
- test model
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Abstract
The invention discloses a human eye optical test model for fundus imaging. The human eye optical test model comprises a cornea lens kit, a pupil, a crystalline lens kit, a transparent liquid, fundus test targets and a cylindrical casing, wherein the fundus test targets can be further divided into resolution test targets and layered structure test targets. The model is in an optical structure of a human eye and conforms to dioptric parameters of the human eye, and two kinds of the test targets are arranged at the fundus position. For single-layer imaging devices such as fundus cameras, the resolution test targets are used, so that the maximum resolution of systems can be detected. For imaging devices such as fundus confocal scanning imaging instruments and fundus optical coherence tomography instruments, which are used for imaging retina deep information, the layered structure test targets are used, so that longitudinal cutting structures of the imaging devices can be presented, and the longitudinal resolution and the transverse resolution of the imaging devices in tissue can be detected and evaluated.
Description
Technical field
The present invention relates to opthalmic optics's test model, relate in particular to a kind of opthalmic optics's test model for fundus imaging.
Background technology
The model of the simulation human eye that exists in the market is divided into two classes substantially: a class is the anatomical model of eyeball, in detail lively displaying comprise the form on cornea, iris, crystalline lens, optical fundus etc., being mainly used in biology or medical teaching uses, understand the physiological structure of eyes for the student, do not possess optical property; Another kind of human-eye model, has certain optical parametric, be mainly used in teaching, making the student to understand the image-forming principle of eyes, or be used for the instrument and equipment that the ophthalmology intern practises using the direct observation eyes such as ophthalmoscope, can not observe the amphiblestroid longitudinal cutting structure in optical fundus with optical detecting method, and not possess quantitative function.
For optical fundus optical coherent chromatographic imaging instrument OCT and optical fundus confocal scanning imager CSLO etc. to fundus imaging to detect the fundus imaging equipment on optical fundus, the present domestic unified standard testing model in the industry that do not have is for the imaging performance parameter of these equipment of evaluation.
Summary of the invention
The problem that exists for solving existing model the invention provides a kind of opthalmic optics's test model, and this model possesses the optical texture of human eye, the dioptric parameter that meets human eye, and at two kinds of tests of position, optical fundus outfit targets, can replace human eye, accurately detect the imaging performance parameter of imaging device.
The object of the present invention is to provide a kind of opthalmic optics's test model for fundus imaging.
Opthalmic optics's test model for fundus imaging of the present invention comprises: corneal lens external member, pupil, lens external member, transparency liquid, optical fundus test target and tubular shell; Wherein, test target in optical fundus is arranged on the bottom of tubular shell; The corneal lens external member arranges the top of tubular shell and with its sealing; Pupil is positioned at the inner surface of corneal lens external member; The lens external member be arranged on pupil inner surface and and optical fundus test target between distance be an image-forming range; In tubular shell, be full of transparency liquid; Image-forming range is the effective focal length of the common lens that form of lens external member, corneal lens external member and transparency liquid; Further, test target in optical fundus is divided into two kinds: resolution test target and hierarchy test target.
The corneal lens external member is equivalent to the cornea of human eye, further comprises corneal lens and corneal lens carriage, and corneal lens is positioned at the central authorities of corneal lens carriage.
Pupil is equivalent to the pupil of human eye, and the center of pupil is provided with through hole, and remainder is lighttight, thereby light enters model by through hole.The diameter of through hole is between 3～8mm.The material of pupil adopts lighttight material, or comprises lighttight material at its outer surface.
The lens external member is equivalent to the crystalline lens of human eye, further comprises crystalline lens carriage and lens, and lens is positioned at the central authorities of crystalline lens carriage.
Transparency liquid is the material close with the refractive index of aqueous humor, such as pure water, normal saline or artificial vitreous etc.
Except the through hole of pupil, other parts of opthalmic optics's test model are lighttight.Can adopt pupil and cylindrical case is lighttight material, perhaps other parts except through hole is wrapped up with lighttight material.
Optical fundus test target is equivalent to the retina of human eye, adopts resolution test target or hierarchy test target.The resolution test target is for being provided with test chart at the bottom of opaque target, test chart adopts the optical resolution test chart of standard, such as 1951USAF (just), NBS1963A (just).For the imaging device of the monolayers such as fundus camera, adopt the resolution test target, by imaging device model is carried out imaging, can the accessible ultimate resolution of detection system.Hierarchy test target material adopts macromolecular material, such as silicone elastomer (silicone elastomer) and acrylic PMMA etc.; The multilamellar that comprises even thickness, the thickness of every one deck is between 30～120 μ m.Every one deck in the hierarchy test target has different refractive indexs, and its absorptance and scattering coefficient are near amphiblestroid optical parametric.In hierarchy test target, be mixed with the nanoparticle of known dimensions, be equivalent in the retina the not homogeneous structure such as blood vessel etc.; The material of nanoparticle can be TiO
2, SiO
2, or golden nanometer particle; The size of nanoparticle is between 200～500nm.For the imaging device to the imaging of retina the deep information such as optical fundus confocal scanning imager and optical fundus optical coherent chromatographic imaging instrument, adopt hierarchy test target, imaging device carries out imaging to model, can present its longitudinal cutting structure, thus longitudinal resolution and the lateral resolution of detecting and assessing imaging device in tissue.
Opthalmic optics's test model of the present invention can replace human eye, is used for detecting the imaging performance parameter of fundus imaging equipment, and imaging device is to the model imaging, and the readability by judging imaging is to detect the imaging performance parameter of these imaging devices.
Advantage of the present invention:
The invention provides a kind of opthalmic optics's test model, this model possesses the optical texture of human eye, the dioptric parameter that meets human eye, and at two kinds of optical fundus tests of position, optical fundus outfit targets, resolution test target and hierarchy test target are respectively applied to its longitudinal resolution and lateral resolution in tissue of the accessible ultimate resolution of detection system and detecting and assessing.
Description of drawings
Fig. 1 is the structural representation of Gullstrand-Le Grand schematic eye;
Fig. 2 is the profile of the opthalmic optics's test model for fundus imaging of the present invention;
Fig. 3 is the structural representation of resolution test target of an embodiment of the opthalmic optics's test model for fundus imaging of the present invention, and wherein (a) is the front view of resolution test target, (b) is the enlarged drawing of test chart;
Fig. 4 is the profile of hierarchy test target of an embodiment of the opthalmic optics's test model for fundus imaging of the present invention.
The specific embodiment
Below in conjunction with accompanying drawing, the present invention will be further described by embodiment.
Fig. 1 is the structural representation of Gullstrand-Le Grand schematic eye, and as shown in Figure 1, human eye comprises cornea 01, aqueous humor 031, pupil, crystalline lens 02, vitreous body 032 and retina 04, each structure parameter such as the following table of this schematic eye:
As shown in Figure 2, according to the schematic eye of above-mentioned human eye, opthalmic optics's test model of the present embodiment comprises: corneal lens external member 1, pupil 2, lens external member 3, transparency liquid, optical fundus test target 4 and tubular shell 5; Wherein, test target 4 in optical fundus is arranged on the bottom of tubular shell 5; Corneal lens external member 1 arranges the top of tubular shell 5 and with its sealing; Pupil 2 is positioned at the inner surface of corneal lens external member 1; Lens external member 3 be arranged on pupil 2 inner surface and and optical fundus test target 4 between distance be an image-forming range.Further, corneal lens external member 1 comprises corneal lens 11 and corneal lens carriage 12, and corneal lens 11 is fixed on the central authorities of corneal lens carriage 12 by pressure ring 13, seals by sealing ring 14 between corneal lens external member 1 and the tubular shell.The center of pupil 2 is provided with through hole, and remainder is lighttight, and for the imaging device that needs mydriasis, the diameter of pupil can reach 8mm, and for the imaging device of exempting from mydriasis, the diameter of pupil is 3～4mm.Lens external member 3 comprises crystalline lens carriage 32 and lens 31, and lens 31 is fixed on the central authorities of crystalline lens carriage 32 by pressure ring 33.
In the present embodiment, design parameter is: lens all adopt MgF
2The planoconvex lens of plated film, corneal lens 11 diameter 12.0mm wherein, focal length 24.0mm; Lens 31 diameter 15.0mm, focal length 22.5mm; Transparency liquid adopts pure water.
Shown in Fig. 3 (a), the resolution test target is to be provided with test chart at the bottom of opaque target, and shown in Fig. 3 (b), test chart adopts 1951USAF (just) the optical resolution test chart of standard.
As shown in Figure 4, hierarchy test target comprise thickness all and four layers, the thickness of every one deck is 50～60 μ m, gross thickness is at 200～240 μ m, this is amphiblestroid approximate thickness.Material adopts silicone elastomer (silicone elastomer).Every one deck in the hierarchy test target has different refractive indexs, tests as required and joins, and the scope of refractive index is between 1.41～1.49, and its absorptance and scattering coefficient are near amphiblestroid optical parametric.In hierarchy test target, be mixed with the nanoparticle of known dimensions, between the size 200～500nm of nanoparticle.
Resolution test target and hierarchy test target are respectively applied to its longitudinal resolution and lateral resolution in tissue of the accessible ultimate resolution of detection system and detecting and assessing, and resolution reaches micron dimension.
It should be noted that at last, the purpose of publicizing and implementing mode is to help further to understand the present invention, but it will be appreciated by those skilled in the art that: without departing from the spirit and scope of the invention and the appended claims, various substitutions and modifications all are possible.Therefore, the present invention should not be limited to the disclosed content of embodiment, and the scope of protection of present invention is as the criterion with the scope that claims define.
Claims (10)
1. opthalmic optics's test model, the imaging performance parameter that is used for evaluation fundus imaging equipment, it is characterized in that, described opthalmic optics's test model comprises: corneal lens external member (1), pupil (2), lens external member (3), transparency liquid, optical fundus test target (4) and tubular shell (5); Wherein, described optical fundus test target (4) is arranged on the bottom of tubular shell (5); Described corneal lens external member (1) is arranged on the top of tubular shell (5) and with its sealing; Described pupil (2) is positioned at the inner surface of corneal lens external member (1); Described lens external member (3) be arranged on pupil (2) inner surface and and optical fundus test target (4) between distance be an image-forming range; In described tubular shell (5), be full of transparency liquid; Described image-forming range is the effective focal length of the common lens that form of lens external member (3), corneal lens external member (1) and transparency liquid; Further, described optical fundus test target (4) is divided into two kinds: resolution test target and hierarchy test target.
2. opthalmic optics's test model as claimed in claim 1, it is characterized in that, described corneal lens external member (1) further comprises corneal lens (11) and corneal lens carriage (12), and described corneal lens (11) is positioned at the central authorities of corneal lens carriage (12).
3. opthalmic optics's test model as claimed in claim 1 is characterized in that, the center of described pupil (2) is provided with through hole, and remainder is lighttight, and the diameter of through hole is between 3～8mm.
4. opthalmic optics's test model as claimed in claim 1, it is characterized in that, described lens external member (3) further comprises crystalline lens carriage (32) and lens (31), and described lens (31) is positioned at the central authorities of crystalline lens carriage (32).
5. opthalmic optics's test model as claimed in claim 1 is characterized in that, described transparency liquid is the material close with the refractive index of aqueous humor.
6. opthalmic optics's test model as claimed in claim 1, it is characterized in that, except the through hole of pupil (2), other parts of described opthalmic optics's test model are lighttight, the material of pupil (2) and cylindrical case is lighttight material, perhaps other parts except through hole is wrapped up with lighttight material.
7. opthalmic optics's test model as claimed in claim 1 is characterized in that, described resolution test target is for being provided with test chart at the bottom of opaque target, and test chart adopts the optical resolution test chart of standard.
8. opthalmic optics's test model as claimed in claim 1 is characterized in that, the material of described hierarchy test target adopts macromolecular material; The multilamellar that comprises even thickness, the thickness of every one deck is between 30～120 μ m.
9. opthalmic optics's test model as claimed in claim 8 is characterized in that, the every one deck in the described hierarchy test target has different refractive indexs, and its absorptance and scattering coefficient are near amphiblestroid optical parametric.
10. opthalmic optics's test model as claimed in claim 1 is characterized in that, is mixed with the nanoparticle of known dimensions in the described hierarchy test target, and the material of nanoparticle is TiO
2, SiO
2, in the gold nano grain one or more; Size is between 200～500nm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310211334.9A CN103315703B (en) | 2013-05-31 | 2013-05-31 | A kind of opthalmic optics's test model for fundus imaging |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310211334.9A CN103315703B (en) | 2013-05-31 | 2013-05-31 | A kind of opthalmic optics's test model for fundus imaging |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103315703A true CN103315703A (en) | 2013-09-25 |
| CN103315703B CN103315703B (en) | 2015-08-12 |
Family
ID=49184961
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310211334.9A Active CN103315703B (en) | 2013-05-31 | 2013-05-31 | A kind of opthalmic optics's test model for fundus imaging |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103315703B (en) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103932675A (en) * | 2014-05-07 | 2014-07-23 | 中国计量科学研究院 | Human eye test model for evaluating three-dimensional imaging performance of OCT equipment of ophthalmology department and use method thereof |
| CN103932682A (en) * | 2014-05-07 | 2014-07-23 | 中国计量科学研究院 | Three-dimensional resolution panel for evaluating imaging performance of OCT equipment and use method thereof |
| CN106880340A (en) * | 2017-03-09 | 2017-06-23 | 广州永士达医疗科技有限责任公司 | A kind of OCT equipment imaging performance evaluating apparatus and its application method |
| CN107478414A (en) * | 2017-08-25 | 2017-12-15 | 广州永士达医疗科技有限责任公司 | A kind of OCT image pumpback performance testing device and method |
| CN107647845A (en) * | 2017-10-30 | 2018-02-02 | 浙江省医疗器械检验院 | A kind of model eye and its application method for eyeground detection |
| CN110680277A (en) * | 2019-09-16 | 2020-01-14 | 中国计量科学研究院 | Ophthalmic optical imaging and biological parameter measuring instrument calibration tool and use method thereof |
| CN110680276A (en) * | 2019-09-16 | 2020-01-14 | 中国计量科学研究院 | Ophthalmic optical imaging and biological parameter measuring instrument calibration tool and use method thereof |
| CN111238778A (en) * | 2019-12-30 | 2020-06-05 | 重庆大学 | Imaging performance detection system for active healthy ophthalmologic image products |
| CN112826439A (en) * | 2020-12-31 | 2021-05-25 | 重庆贝奥新视野医疗设备有限公司 | Ophthalmic optics coherence tomography instrument measuring device |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020085172A1 (en) * | 2000-12-29 | 2002-07-04 | Altmann Griffith E. | Lens-eye model and method for predicting in-vivo lens performance |
| US20040189934A1 (en) * | 2003-03-25 | 2004-09-30 | Niven Gregg D. | Eye model for measurement |
| JP4653906B2 (en) * | 2001-06-21 | 2011-03-16 | 株式会社トプコン | Model eye for optometry equipment |
| US20110170059A1 (en) * | 2008-06-17 | 2011-07-14 | Klaus Ehrmann | Physical model eye systems and methods |
| US20110249236A1 (en) * | 2010-04-13 | 2011-10-13 | Canon Kabushiki Kaisha | Schematic eye and adjustment method and evaluation method for optical coherence tomography apparatus |
| CN203354522U (en) * | 2013-05-31 | 2013-12-25 | 北京大学 | Human eye optic test model |
-
2013
- 2013-05-31 CN CN201310211334.9A patent/CN103315703B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020085172A1 (en) * | 2000-12-29 | 2002-07-04 | Altmann Griffith E. | Lens-eye model and method for predicting in-vivo lens performance |
| JP4653906B2 (en) * | 2001-06-21 | 2011-03-16 | 株式会社トプコン | Model eye for optometry equipment |
| US20040189934A1 (en) * | 2003-03-25 | 2004-09-30 | Niven Gregg D. | Eye model for measurement |
| US20110170059A1 (en) * | 2008-06-17 | 2011-07-14 | Klaus Ehrmann | Physical model eye systems and methods |
| US20110249236A1 (en) * | 2010-04-13 | 2011-10-13 | Canon Kabushiki Kaisha | Schematic eye and adjustment method and evaluation method for optical coherence tomography apparatus |
| CN203354522U (en) * | 2013-05-31 | 2013-12-25 | 北京大学 | Human eye optic test model |
Cited By (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103932682A (en) * | 2014-05-07 | 2014-07-23 | 中国计量科学研究院 | Three-dimensional resolution panel for evaluating imaging performance of OCT equipment and use method thereof |
| CN103932682B (en) * | 2014-05-07 | 2015-10-28 | 中国计量科学研究院 | A kind of dimensional resolution plate for the evaluation of OCT equipment imaging performance and using method thereof |
| CN103932675B (en) * | 2014-05-07 | 2016-04-13 | 中国计量科学研究院 | A kind of test person eye model for ophthalmology OCT equipment three-dimensional imaging performance evaluation and using method thereof |
| CN103932675A (en) * | 2014-05-07 | 2014-07-23 | 中国计量科学研究院 | Human eye test model for evaluating three-dimensional imaging performance of OCT equipment of ophthalmology department and use method thereof |
| CN106880340A (en) * | 2017-03-09 | 2017-06-23 | 广州永士达医疗科技有限责任公司 | A kind of OCT equipment imaging performance evaluating apparatus and its application method |
| WO2018161386A1 (en) * | 2017-03-09 | 2018-09-13 | 广州永士达医疗科技有限责任公司 | Device for evaluating imaging performance of oct apparatus, and method for using same |
| CN106880340B (en) * | 2017-03-09 | 2020-03-13 | 广州永士达医疗科技有限责任公司 | OCT equipment imaging performance evaluation device and using method thereof |
| CN107478414B (en) * | 2017-08-25 | 2023-09-22 | 广州永士达医疗科技有限责任公司 | OCT imaging back-pumping performance testing device and method |
| CN107478414A (en) * | 2017-08-25 | 2017-12-15 | 广州永士达医疗科技有限责任公司 | A kind of OCT image pumpback performance testing device and method |
| CN107647845A (en) * | 2017-10-30 | 2018-02-02 | 浙江省医疗器械检验院 | A kind of model eye and its application method for eyeground detection |
| CN107647845B (en) * | 2017-10-30 | 2024-02-23 | 浙江省医疗器械检验院 | Model eye for fundus detection and application method thereof |
| CN110680277A (en) * | 2019-09-16 | 2020-01-14 | 中国计量科学研究院 | Ophthalmic optical imaging and biological parameter measuring instrument calibration tool and use method thereof |
| CN110680277B (en) * | 2019-09-16 | 2021-08-27 | 中国计量科学研究院 | Ophthalmic optical imaging and biological parameter measuring instrument calibration tool and use method thereof |
| CN110680276B (en) * | 2019-09-16 | 2021-08-27 | 中国计量科学研究院 | Ophthalmic optical imaging and biological parameter measuring instrument calibration tool and use method thereof |
| CN110680276A (en) * | 2019-09-16 | 2020-01-14 | 中国计量科学研究院 | Ophthalmic optical imaging and biological parameter measuring instrument calibration tool and use method thereof |
| CN111238778A (en) * | 2019-12-30 | 2020-06-05 | 重庆大学 | Imaging performance detection system for active healthy ophthalmologic image products |
| CN112826439A (en) * | 2020-12-31 | 2021-05-25 | 重庆贝奥新视野医疗设备有限公司 | Ophthalmic optics coherence tomography instrument measuring device |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103315703B (en) | 2015-08-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103315703B (en) | A kind of opthalmic optics's test model for fundus imaging | |
| US20220125310A1 (en) | Implantable Micro-Fluidic Device for Monitoring of Intra-Ocular Pressure | |
| CN203354522U (en) | Human eye optic test model | |
| Perinchery et al. | High resolution iridocorneal angle imaging system by axicon lens assisted gonioscopy | |
| WO2006001013A2 (en) | Goggles for improved ocular vision | |
| CN107647845A (en) | A kind of model eye and its application method for eyeground detection | |
| WO2020005053A1 (en) | Portable system for identifying potential cases of diabetic macular oedema using image processing and artificial intelligence | |
| JP2021164720A (en) | Reducing errors of optical measurements of internal pressure of body performed with optical member in contact with body | |
| Camara et al. | A comprehensive review of methods and equipment for aiding automatic glaucoma tracking | |
| NL2021870B1 (en) | A hand-held screening device for remote ophthalmic diagnostics, a method and a computer program product | |
| CN208573723U (en) | A kind of model eye for eyeground detection | |
| Asher et al. | Etiology of Keratoconus: proposed biomechanical pathogenesis | |
| US10531794B1 (en) | Photorefractive flash device and system | |
| Kjersem et al. | Transillumination imaging of intraocular tumours | |
| US20220215584A1 (en) | Apparatus for Calibrating Retinal Imaging Systems and Related Methods | |
| EP3714765B1 (en) | Device and method for obtaining mechanical, geometric, and dynamic measurements of optical surfaces | |
| Pugalendhi et al. | Development of 3D Printed Smartphone-Based Multi-Purpose Fundus Camera (MultiScope) for Retinopathy of Prematurity | |
| Chen et al. | Retinal optical coherence tomography image analysis | |
| ES2713272B2 (en) | Eye test bench | |
| CN210158736U (en) | Intraocular lens | |
| Kaushik et al. | Imaging and qualitative depth analysis with a portable nonmydriatic fundus camera using oblique illumination | |
| JP2021037253A (en) | Laminate, inspection device and model eye | |
| WO2009130346A1 (en) | Device for measuring amplitude of accommodation | |
| Cliquet Jr et al. | Biomedical Engineering Systems and Technologies: 11th International Joint Conference, BIOSTEC 2018, Funchal, Madeira, Portugal, January 19–21, 2018, Revised Selected Papers | |
| Williams | Computational Methods to Quantify Human Lens Shape and Optical Properties Using Laser Ray Tracing and Optical Coherence Tomography |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |