CN102222533B - Automatic assembly type photodynamic drill based on multi-core fiber - Google Patents
Automatic assembly type photodynamic drill based on multi-core fiber Download PDFInfo
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- CN102222533B CN102222533B CN 201110113782 CN201110113782A CN102222533B CN 102222533 B CN102222533 B CN 102222533B CN 201110113782 CN201110113782 CN 201110113782 CN 201110113782 A CN201110113782 A CN 201110113782A CN 102222533 B CN102222533 B CN 102222533B
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Abstract
The invention provides an automatic assembly type photodynamic drill based on multi-core fiber. The automatic assembly type photodynamic drill comprises front optical tweezers and a micro rotor formed by processed multi-core fiber. In solution the optical tweezers automatically captures the micro rotor to form a photodynamic drill. The micro rotor structure comprises a ball, a rotating shaft, a windmill like rotor structure composed of a plurality of wings and a cone tip, wherein the ball is at the top of the rotating shaft, the windmill like rotor structure composed of a plurality of wings is at the middle of the rotating shaft, and the cone tip is at the bottom of the rotating shaft. According to the invention, the micro rotor ball can automatically form a photodynamic drill once captured. The photodynamic drill has the advantages of convenient operation, simple structure, and easy control. The dimension of the photodynamic drill is micron-sized, and the rotating speed is easy to control from outside. The photodynamic drill can be applied to microbe punching such as cell wall punching. Accordingly, the automatic assembly type photodynamic drill based on multi-core fiber provides a strong tool for micro life science and biomedical researches.
Description
Technical field
What the present invention relates to is a kind of smooth power drill, specifically a kind of self assembling type light power drill based on multi-core fiber.
Background technology
Photic rotation is the effective means that realizes the micromechanics motor, development along with science and technology, and the development of processes technology and computer technology, the application prospect of photic rotation is with increasingly extensive, the method of photic rotation not only can be applied to serves as stirrer in the micro-total analysis system, can also be applied in the Micropump, also can be used for studying microscopic property, cell membrane shearing force, little brill of rotation motor albumen, fluid etc., therefore, the further investigation of this technology provides a kind of strong instrument for little life science and biomedicine.
1936, the half-wave plate that R.A.Beth allows a branch of circularly polarized light hang by filament experimentally, utilize first the angular momentum of photon in the light beam to realize rotation (the Beth R A.Mechanical detection and measurement of the angualarmomentum of light.Phys.Rev. of object, 1936,50:115-125).People are ceaselessly exploring the method that realizes photic rotation always since then.Since having proposed " light tweezer ", the people such as Askin in 1986 realized the three dimensions of particle is controlled (Ashkin, J.M.Dziedzic, J.E.Bjorkholm, S.Chu.Observation of a single-beam gradient force opticaltrap for dielectric particles.Opt.Lett.1986,11,288-290.), also promoted the development of photic rotation simultaneously.Up to the present realize the following several modes of the main employing of optical drive rotation: first kind of way is to utilize spin angular momentum to realize rotation; The second way is to utilize orbital angular momentum to realize rotation; The third mode is to utilize the linear momentum of light to realize rotation, design and produce the microdevice with given configuration structure, utilize device the interactions such as the reflection of light beam, refraction, absorption to be realized rotation (the Galajda P of device, Ormos P.Complex Micromachines Produced and Driven by Light.Appl.Phys.Lett.2001,78 (2): 249-251).Utilize the third mode to realize that the research and comparison that rotates is many, because the rotating speed of particulate and direction can manual controls, and the Arbitrary 3 D micro element that utilizes two-photon polymerized technology to process to be suitable for optical drive, so that this experimental technique implements is more flexible, therefore, there is at present more researchist to be devoted to motors designs research and improvement.
The Ormos group of Hungary academy of sciences has also done a large amount of research work in this respect, the rotor that has proposed multiple special shape is also verified by experiment, utilize laser optical tweezer to capture and drive the rotor of helical structure, comprise propeller shape, spiral yarn shaped, water sprinkler shape, contrasting under the same conditions through experimental verification, the propeller shape rotor can obtain higher rotating speed, can reach several hertz speed of rotation (Peter Galajda under the power of 10mw, Pal Ormos.Rotation of microscopic propellers in lasertweezers.Journal of Optics B:Quantum and Semiclassical Optics 2002,4 (2), pp.S78-S81); In order to obtain continuous rotation control mode, after the laser optical tweezer that the people such as Ormos are produced linearly polarized light according to flaky particles is captured rotation, sense of rotation is consistent with the plane of polarization direction, therefore having designed with xsect is cross gear particle, although sense of rotation is easy to control, the torsional moment that produces under the identical condition is less; In addition, in order to obtain better experimental result, Ormos and his colleague propose again a plurality of rotor combination formative gear driving devices, utilize center rotor to rotate and drive other rotor.Consider the complicacy of laser optical tweezer device, it is more useful to use Waveguide to drive under some is used, especially in micro-fluidic system, so they have proposed again integrated system, comprise the light rotor, optical axis and the optical waveguide of utilizing two-photon polymerized method to form, Waveguide power input 10mw can produce the 2rps speed of rotation.
Japan Ukita group of Ritsumeikan University, multiple rotor structure such as simple shuttlecock shape have also been proposed, be with bevelled shuttlecock shape, comprising three wings, four wings and a plurality of wing and cylindrical rotor (H.Ukita with ramp structure, M.Kanehira.Ashuttlecock optical rotor-Its design, fabrication and evaluation for a micro-fluidic mixer.IEEEJournal of Selected Topics in Quantum Electronics on Optical MEMS, 8, pp.111-117,2002.), calculate luminous power square and viscous resistance by theory, and verify by experiment.These rotor structures all can be realized stablizing and capture, High Rotation Speed; Simultaneously by theoretical calculate and the parameters of emulation light beam such as light intensity, numerical aperture, focal length etc. to the influence of rotation speed of rotor, thereby optimized beam characteristics and rotor structure.The people such as Ukita consider the impact of viscosity resistance in the micro-fluidic system, have proposed cylindrically can reduce viscosity resistance making with the side of bevelled rotor, thereby have obtained higher rotating speed and performance.In order in micro-fluidic system, to give full play to the effect of stirrer, they have proposed again to realize by the position of displacement laser optical tweezer ligh trap the counterclockwise and clockwise variation of rotor, at first two rotors with three wings are coupled together, whole through Ear Mucosa Treated by He Ne Laser Irradiation, the rotating speed of acquisition is 2 times of single rotor.Based on this design concept, the people such as Shoii Maruo have also designed a kind of composite fabricated rotor, two rotors that will have the reverse direction wing connect, and cylindrical jacket of surface cover outside two rotors, purpose is to fix two rotors and reduce viscosity resistance, then focuses the laser beam to the centre of two rotors, so that it is identical to be applied to the light pressure direction of the rotor wing, therefore increase the light torsional moment, can obtain higher rotating speed.
The Vincent L.Y.Loke of Queensland university is in order better to be applied to the light motor in the biologic applications, can control at any time flow direction and the position of sample solution, design and utilize two-photon polymerized technology to prepare shape and be similar to the vaned rotor of dumbbell shaped Intermediate Gray, under multiple beam drives, realize rotating, obtained higher stirring efficiency.(Gregor
SimonParkin, Timo A.Nieminen, Vincent L.Y.Loke, Norman R.Heckenberg, and Halina Rubinsztein-DunlopIntegrated optomechanical microelements.Optics Express, 2007,15 (9), pp.5521-5530) in order to obtain better experiment effect, the various ways that they propose to produce torsional moment combines, at first with two rotor combinations, then utilize light beam with angular momentum to shine and obtain comparatively ideal result.
Yellow civilian great group of Chinese University of Science and Technology utilizes the two-photon polymerized effect of a kind of propenoic acid ester photocureable material S-3, processing diameter in the femtosecond laser microfabrication system of voluntarily development is 6 microns the little rotor of fylfot, and the photic rotation of 200rpm (is wished stable when utilizing light forceps device to realize laser power 50mW, Liu Yuxiang, Guo Rui, Xiao Shizhou, Huang Wenhao. a kind of Laser Processing of miniature rotor and photic rotation. photoelectric project .2006 (33): 10-13), the method of several calculating light moments of torsion has also been proposed simultaneously, and utilizing the method that several special rotor that Ormos group once designed has been carried out theoretical calculating, the result who obtains conforms to substantially with experiment.
There are many universities in the whole world according to " class Windmill rotary " principle, done more research in the rotor shapes design, obtained larger progress and achievement in research preferably, but or exist can not be stable such as rotor rotation, the restrictions such as drive unit are so that range of application is limited.
Summary of the invention
The object of the present invention is to provide a kind of easy to operate, simple in structure, easy to control, the self assembling type light power drill based on multi-core fiber that rotating speed is controlled by the external world.
The object of the present invention is achieved like this: comprise light tweezer and little rotor that the multi-core fiber of front end after processing forms, front end consists of the light power drill through the light tweezer that the multi-core fiber after the processing forms is captured little rotor automatically in solution after; " class windmill " rotor structure and cone that described little rotor structure comprises spheroid, turning axle, be made of a plurality of wings are most advanced and sophisticated, spheroid is positioned at the turning axle top, " class windmill " rotor structure that is made of a plurality of wings is positioned at the turning axle middle part, and the cone tip is positioned at the turning axle bottom.
The present invention can also comprise like this some architectural features:
1, " class windmill " rotor structure of consisting of of the described a plurality of wing comprises 3-6 the wing, and each wing is the column on inclined-plane above being.
2, the outer end of each wing is with semicolumn.
3, the multi-core fiber of described front end after processing is that the multi-core fiber front end is formed chamfering α behind precise finiss processing or fused biconical taper, the satisfied pi/2-arcsin (n that concerns of chamfering α
Liquid/ n
Core)＜α＜pi/2 forms optical trap and captures little rotor spheroid.
4, how much distributions of the fibre core of described multi-core fiber are to be three core fibres of equilateral triangle distribution or to be the square profile four-core fiber.
5, for can producing moment of torsion with interactions such as beam reflection, refraction, absorptions, the rotor structure with three wings or a plurality of wings realizes rotation in the middle part of described little rotor.Described little two ends of rotor is symmetrical spheroid, turning axle, and rotation is realized for the rotor structure with three wings or a plurality of wings can produce moment of torsion with interactions such as beam reflection, refraction, absorptions in the centre.
The invention provides a kind of self assembling type light power drill based on multi-core fiber of novelty, it consists of light power drill system after mainly automatically capturing the spheroid of little rotor through the light tweezer that the multi-core fiber after the retrofit forms by front end in solution voluntarily; Little rotor structure comprises top spheroid, turning axle, connection with " class windmill " rotor structure of a plurality of wings of inclined-plane and semicolumn, and the bottom is that cone is most advanced and sophisticated; After wherein the front end of multi-core fiber was captured spheroid, when playing the dead axle effect, the emergent light vertical irradiation was realized rotation to being with the bevelled wing, drives simultaneously the effect that the light power drill is played in bottom cone rotation.Because in a single day little rotor spheroid is captured capable of automatic assembling for the light power drill, easy to operate, simple in structure, easy to control, and the light power drill is of a size of micron order, and rotating speed is controlled by the external world, can be widely applied in the microorganism punching to hole such as cell membrane.Therefore, provide a kind of strong instrument for little life science and biomedical research.
The present invention has following features:
1, the invention provides a kind of novel self assembling type light power drill based on multi-core fiber, form optical trap after utilizing multi-core fiber through precise finiss processing or fused biconical taper and capture little rotor, volume is little, saved physical space, processing ease, it is large to control scope, simple in structure, can realize that artificial outside controls.
2, in a single day little rotor spheroid is captured, and emergent light shines simultaneously is with the bevelled wing, realizes rotation, drives simultaneously the effect that the light power drill is played in bottom cone rotation, has realized that self assembly joins.
3, the light power drill is of a size of micron order, and rotating speed is controlled by the external world, can be widely applied in the microorganism punching to hole such as cell membrane.Therefore, provide a kind of strong instrument for little life science and biomedical research.
Description of drawings
Fig. 1 is based on the self assembling type light power drill synoptic diagram of multi-core fiber;
The multi-core fiber synoptic diagram of Fig. 2 fine gtinding processing;
Multi-core fiber structural representation behind Fig. 3 fused biconical taper;
Fig. 4 multi-core fiber fused biconical taper synoptic diagram;
Fig. 5 three core fibre cross sectional representation;
Fig. 6 four-core fiber cross sectional representation;
The little rotor structure synoptic diagram of Fig. 7
The little rotor top view of Fig. 8;
The little rotor front view of Fig. 9.
Embodiment
The present invention is described in more detail as an example of three core fibres example below in conjunction with accompanying drawing:
In conjunction with Fig. 1,3, it consists of light power drill system after mainly automatically capturing the spheroid of little rotor 5 through the light tweezer 4 that the multi-core fiber 1 after the retrofit forms by front end in solution voluntarily; Simultaneously in conjunction with Fig. 7-9, little rotor structure comprises top spheroid, turning axle, connection with " class windmill " rotor structure of a plurality of wings of inclined-plane and semicolumn, and the bottom is that cone is most advanced and sophisticated; After wherein the front end of multi-core fiber was captured spheroid, when playing the dead axle effect, the emergent light vertical irradiation was realized rotation to being with the bevelled wing, drives simultaneously the effect that the light power drill is played in bottom cone rotation.The multi-core fiber of described front end after retrofit, be with the multi-core fiber front end behind precise finiss processing or fused biconical taper, chamfering α satisfies and concerns pi/2-arcsin (n
Liquid/ n
Core)＜α＜pi/2 forms optical trap and captures little rotor spheroid.It is to be three core fibres of equilateral triangle distribution and to be the square profile four-core fiber that the fibre core of described multi-core fiber distributes for how much.Rotation is realized for the rotor structure with three wings or a plurality of wings can produce moment of torsion with interactions such as beam reflection, refraction, absorptions in described little rotor middle part.Described little two ends of rotor is symmetrical spheroid, turning axle, and rotation is realized for the rotor structure with three wings or a plurality of wings can produce moment of torsion with interactions such as beam reflection, refraction, absorptions in the centre.
The below illustrates manufacturing process of the present invention:
Manufacturing process gives an example 1:
1, grinding the cone multi-core fiber makes: get one section fibre core, three core fibres, 1 front end that is equilateral triangle that distributes and carry out fine gtinding, become cone shape 4, in order to guarantee can to form cross one another beam combination after emergent light is through the circular conical surface refraction, semi-cone angle α is controlled at pi/2-arcsin (n
Liquid/ n
CoreIn the scope of)＜α＜pi/2.For fiber core refractive index n
Core=1.4868, cladding index n
Cladding=1.4571, and the residing liquid refractivity n of optical fiber optical tweezers
WaterIn=1.333 the situation, the scope of this semi-cone angle should be controlled between 26.3 °-90 °;
2, cone polishing: above-mentioned ground optical fiber cone is polished, after microscopically is qualified through detection, be placed on cleaning, dry for standby in the ultrasonic cleaning tank;
3, the processing of little rotor: wherein the processing of fine particle as shown in Figure 7, the model of designing institute demand in CAD at first, then the application program that has designed according to CAD, be converted into the instruction that controller can be identified, the software control system of recycling computing machine is controlled the break-make of precise motion and the optical gate of three-dimensional shifting axle, realize the selective processing of femtosecond laser, this moment, the femtosecond laser collimation was rear from microscope left side incident, through after the mirror reflects, focused in the photosensitive resin by 100 x Microscope Objectives, photosensitive resin is positioned at surface of glass slide, slide is fixed on the three-dimensional shifting axle, thereby in photosensitive resin, make the 3 D stereo micro element, unexposed material dissolution with solvents, just obtaining required curing three-dimensional microstructures is designed little rotor.
Manufacturing process gives an example 2:
1, the cone multi-core fiber behind the fused biconical taper is made: in conjunction with Fig. 3,4, the optical fiber end of three core fibres 1 is carried out fused biconical taper, be heated to soft state, then draw cone, the fibre core spacing of multi-core fiber is from along with drawing pitch cone radius to dwindle from proportional, until semi-cone angle α is controlled at pi/2-arcsin (n
Liquid/ n
CoreStop to draw cone in the scope of)＜α＜pi/2.For fiber core refractive index n
Core=1.4868, cladding index n
Cladding=1.4571, and the residing liquid refractivity n of optical fiber optical tweezers
WaterIn=1.333 the situation, the scope of this semi-cone angle should be controlled between 26.3 °-90 °;
2, the processing of little rotor: wherein the processing of fine particle as shown in Figure 7, the model of designing institute demand in CAD at first, then the application program that has designed according to CAD, be converted into the instruction that controller can be identified, the software control system of recycling computing machine is controlled the break-make of precise motion and the optical gate of three-dimensional shifting axle, realize the selective processing of femtosecond laser, this moment, the femtosecond laser collimation was rear from microscope left side incident, through after the mirror reflects, focused in the photosensitive resin by 100 x Microscope Objectives, photosensitive resin is positioned at surface of glass slide, slide is fixed on the three-dimensional shifting axle, thereby in photosensitive resin, make the 3 D stereo micro element, unexposed material dissolution with solvents, just obtaining required curing three-dimensional microstructures is designed little rotor.
Claims (4)
1. self assembling type light power drill based on multi-core fiber, it is characterized in that: comprise light tweezer and little rotor that the multi-core fiber of front end after processing forms, front end consists of the light power drill through the light tweezer that the multi-core fiber after the processing forms is captured little rotor automatically in solution after; " class windmill " rotor structure and cone that described little rotor structure comprises spheroid, turning axle, be made of a plurality of wings are most advanced and sophisticated, spheroid is positioned at the turning axle top, " class windmill " rotor structure that is made of a plurality of wings is positioned at the turning axle middle part, and the cone tip is positioned at the turning axle bottom.
2. the self assembling type light power drill based on multi-core fiber according to claim 1 is characterized in that: " class windmill " rotor structure that described a plurality of wings consist of comprises 3-6 the wing, and each wing is the column on inclined-plane above being.
3. the self assembling type light power drill based on multi-core fiber according to claim 2, it is characterized in that: the outer end of each wing is with semicolumn.
4. according to claim 1,2 or 3 described self assembling type light power drills based on multi-core fiber, it is characterized in that: it is to be three core fibres that equilateral triangle distributes or to be the square profile four-core fiber that the fibre core of described multi-core fiber distributes for how much.
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| CN108267815B (en) * | 2018-02-09 | 2019-12-13 | 哈尔滨工业大学 | micro-nano optical motor based on coupling of waveguide and resonant cavity and driving method thereof |
| CN113687469A (en) * | 2021-08-26 | 2021-11-23 | 桂林电子科技大学 | Multifunctional optical fiber micro-impact gun tool |
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| EP1966635A2 (en) * | 2005-12-21 | 2008-09-10 | Koninklijke Philips Electronics N.V. | Fluid focus lens to isolate or trap small particulate matter |
| EP2311045B1 (en) * | 2008-07-22 | 2013-03-13 | Centre National de la Recherche Scientifique (C.N.R.S) | Method for reducing interference and crosstalk in double optical tweezers using a single laser source, and apparatus using the same |
| CN101881858B (en) * | 2010-06-11 | 2012-07-11 | 哈尔滨工程大学 | Satellite-type helical multi-core fiber optical micro-tweezers capable of achieving rotation of small particles and preparation method thereof |
| CN101907742B (en) * | 2010-06-21 | 2012-07-11 | 哈尔滨工程大学 | Array optical tweezers based on multicore polarization-preserving fiber and manufacturing method thereof |
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Non-Patent Citations (6)
| Title |
|---|
| Integrated optical motor;Lorand kelemen,Sandor Valkai,Pal Ormos;《APPLIED OPTICS》;20060420;第45卷(第12期);2777-2780 * |
| Lorand kelemen,Sandor Valkai,Pal Ormos.Integrated optical motor.《APPLIED OPTICS》.2006,第45卷(第12期),2777-2780. |
| Peter Galajda,Pal Ormos.Rotation of microscopic propellers in laser tweezers.《Journal of Optics B:quantum and semiclassical optics》.2002,s78-s81. |
| Rotation of microscopic propellers in laser tweezers;Peter Galajda,Pal Ormos;《Journal of Optics B:quantum and semiclassical optics》;20020328;s78-s81 * |
| 孙玉芬等.激光光阱中微粒的光致旋转.《激光与光电子学进展》.2003,第40卷(第10期),23-28. |
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